Mood Stabilizers

Question 1

Lithium therapeutic range

Answer 1

0.5-1.5 mEq/L

Question 2

Lithium dosing

Answer 2

Acute Mania = 300mg, 2-3x/day
Long Term = 300-600 mg, 2-3x/day (7yo +)
Extended release = 600 mg, 2-3x/day (12yo+) max = 1200 mg

Question 3

Lithium toxicity

Answer 3

ataxia, coarse tremors, neuromuscular irritability, seizures, coma death.

mild = 1.5-2 dizzy and weak
mod = 2-2.5 anorexia, n/v, blurry vision, hyperreflexia
severe = >2.5 renal failure, oliguria, seizure