Mood Stabilizers Flashcards
Lithium Dosing (acute)
1200 to 2400 mg daily
Lithium SE
Nausea, fine hand tremors, increased urination and thirst
Lithium toxicity symptoms
slurred speech, confusion, severe GI effects
Lithium therapeutic rage
- 6 to 1.2 (maintenance)
0. 8 to 1.2 (acute)
Lithium maintenance dosing
900 to 1200 mg a day
Lithium need to know
concurrent use of NSAID and Ace inhibitor will double lithium levels
Valproic Acid (Depakote) Dosing
15 to 40 mg/kg day
Depakote SE
nausea, dizziness, Abd cramps, sedation, tremor
Depakote dangerous SE
Stevens Johnson syndrome
Depakote is more effective than lithium for
rapid cycling and mixed bipolar
Lamotrigine (Lamictal) dose
25 - 600 mg a day
Depakote therapeutic plasma level
50 to 125 mcg/ml
Depakote loading dose
20 mg/kg
Lamotrigine SE
dizziness, ataxia, somnolence, diplopia, nausea, headache, hepatotoxicity
Lamotrigine rare SE
life-threatening rash, including Stevens Johnson syndrome)