Mood Dxs Flashcards
major depressive episodes. how long to have? how many sxs?
SIGECAPS. at least 5 for two weeks.
man with parkinsons taking levodopa carbipoda with depressive sxs for 3 weeks. what is diagnosis?
major depressive episode NOT normal rxn to medical condition and NOT reaction to drug
SIG E CAPS
sleep, interest, guilt, energy, concentration, appetite, psychomotor activity, suicidal ideation
what percent of manic pts have psychotic sxs
75%
what endocrinopathies can cause a depressive episode
cushings/addisons, hypoglycemia, hypo/hyperthyroidism, hyper/hypocalcemia
what cancers can cause depressive episodes
pancreatic carcinoma, lymphoma
can virus cause depression
mononucleosis
what dementia can cause depression
Parkinsons
what are medical causes of mania
hyperthyroidism, neoplasm, temporal lobe seizures, MS,
what meds can cause mania
corticosteroids, sympathomimetics, dopamine agonists, antidepressants, bronchodilators, levodopa
ethnic and socioeconomic differences in MDD
none
sleep changes in MDD
mutliple awakenings, initial and terminal insomnia, hypersomnia, REM shifted to earlier in night and stages 3 and 4 decreased
neuroendocrine abnormalities of MDD
low serotonin in CSF, high cortisol, hyperactivity in hypothalamic-pituitary- can’t suppress cortisol in dexamethasone suppression test, abrnomal thyroid axis- blunted response of TSH to TRH
catatonic depression? how to treat?
features include cataplexy (immobility), purposeless motor activity, extreme negativism or mutism, bizarre postures, and echolalia. treat with antidepressants and antipsychotics.
what percent of bipolar people treated with lithium experience significant improvement in sxs
50-60%
