Mood disorders Flashcards

1
Q

What is the most appropriate antidepressant to prescribe following an MI

A

Setraline

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2
Q

antidepressant of choice if required in children/adolescents

A

fluoxetine

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3
Q

why are MAOIs not routinely used?

what are they reserved for?

A

they can cause hypertensive crisis if you dont stick to strict dietary requirements (no tyramine containing foods)

Reserved for atypical depression

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4
Q

tx of hypertensive crisis

A

alpha blockade

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5
Q

adverse effects of SSRIs

A

sexual dysfunction, short term anxiety..

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6
Q

which antidepressants can have adverse effects on cardiac function?

A

TCAs

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7
Q

BZD overdose, antagonist?

A

flumazenil

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8
Q

1st line drug tx for anxiety

A

BZD but recommended short term to avoid dependence

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9
Q

Endocrine changes in major depression

A

^ CRH in CSF
^ secretion of cortisol
»» hippocampus SHRINKS in response to cortisol, and the hippocampus is essential in short term memory function
enlarged adrenal glands
50-70% fail to suppress cortisol following dexamethasone

^TRH in CSF

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10
Q

atypical depression features

A
mood reactivity
significant weight gain
hypersomnia
leaden paralysis
interpersonal rejection sensitivity
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11
Q

waking > 2 hrs before usual, depression worse in morning, loss of appetite etc… is a feature of ?

A

somatic syndrome

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12
Q

Hypomanic episode - abnormally elevated/irritable mood for how long?

A

more than or equal to 4 days

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13
Q

manic episode - sustained for how long?

A

more than or equal to a week

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14
Q

True or False: 1/3 of sufferers of panic disorder develop agoraphobia

A

false, 2/3!!!!

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15
Q

What percentage of those with social phobia abuse alcohol

A

20%

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16
Q

1st line medical tx of GAD

A

SSRIs

17
Q

OCD - symptoms have to be occurring for ??

A

over an hour per day

18
Q

38% of obsessions in OCD are related to ?

A

dust. germs ..

19
Q

is heritability high or low in OCD?

A

high

20
Q

1st line tx in OCD

A

exposure and response prevention (ERP)

21
Q

what is the desired effect of antipsychotics

A

DA blockade in the mesolimbic circuits

22
Q

Bipolar 1 - has to have met criteria for ?

A

mania

23
Q

bipolar 2

A

never met manic criteria

but its NOT a milder form!!

24
Q

bipolar 3

A

hypomanic episode only occurs following antidepressants

25
Q

does a single episode of hypomania/mania class as bipolar disorder?

A

yes, even if you have net been depressed yet

26
Q

what do most sufferers of panic disorder develop

A

agoraphobia

27
Q

1st line OCD tx

A

exposure and response prevention (ERP) - highly effective in OCD

28
Q

multiple recurrent and frequently changing physical symptoms

A

somatisisation

29
Q

deliberately producing false symptoms

A

factitious disorder

30
Q

% of non epileptic attack disorder that actually have epilepsy

A

10%

31
Q

feigning illness for secondary gain

A

malingering

32
Q

Cluster A personality disorders

A

“weird”

  • schizoid (aloof)
  • schizotypical (awkward)
  • paranoid (accusatory)
33
Q

Cluster B personality disorders

A

“wild”

  • borderline
  • antisocial (bad)
  • histrionic (bullshit)
  • narcissistic (best)
34
Q

Cluster C personality disorders

A

“worried:

  • avoidant (coward)
  • obsessive-compulsive (compulsive)
  • dependent (clingy)
35
Q

first line drug treatment for panic disorder

A

SSRI

36
Q

conversion disorder

A

typically involves loss of motor or sensory function (may seem to be a stroke)
patient does NOT consciously feign the symptoms

37
Q

dissociative disorder

A

psych symptoms - amnesia, stupor, fugue (forgetting personal identity, memories etc)