Mood Disorders Flashcards

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1
Q

Mood disorders have to cause what

A
  1. social impairment

2. occupational impairment

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2
Q

Define dysthymia

Effect on work

A

Persistent low grade depression for 2 years

They are functioning but can’t be at full potential

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3
Q

What is double depression

A

Dysthymia plus another major depressive disorder

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4
Q

Bipolar Type I vs Type II:

  1. Hospital
  2. Hypomanic symptom
A
  1. Type I more likely in hospital

2. Type II more likely to be hypomanic

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5
Q

What endocrine disorder mimics depression

A

Hypothyroidism

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6
Q

Symptoms of Depression

A

SIGECAPS

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7
Q

Sex difference in depression

A

Females more

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8
Q

Change in depression demographics

A

Earlier onset

Increased rate

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9
Q

Average age of depression onset

A

29

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10
Q

3 parts of depression treatment

A
  1. Psychotherapy
  2. Drug therapy
  3. Other therapy (ECT)
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11
Q

3 goals of treatment

A
  1. Treat symptoms
  2. Restore function
  3. Prevent recurrence
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12
Q

Are newer anti-depressants more effective?

A

No

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13
Q

What is the difference in newer generations of anti-depressants?

A

Less side effects

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14
Q

MAO-I’s first used when

A

1950s

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15
Q

When were TCA’s most often used

A

1960’s through 1980’s

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16
Q

4 ways antidepressants work

A
  1. Block reuptake of serotonin
  2. Block reuptake of norepinephrine
  3. Block reuptake of dopamine
  4. Inactivate monoamine oxidase
17
Q

Dopamine problems are related to what depression symptoms

A

Lack of pleasure and motivation

18
Q

Norepinephrine problems are related to what depression symptoms

A

Lack of energy and alertness

19
Q

Serotonin problems are related to what depression symptoms

A

Obsessions and compulsions

20
Q

MAO-IA food interaction

A

Tyramine

21
Q

Anti-depressants have a BBW of waht

A

Increased suicidality in 18-24 year olds

22
Q

What is the onset of bipolar

A

14 to 24

23
Q

70% of bipolar are mis diagnosed as what

A

Having major depression

24
Q

Which state of bipolar is most common

A

Depressive state

25
Q

% of bipolar that commit suicide

A

20%

26
Q

What % of bipolar are not diagnosed

A

half

27
Q

Define mania

A

Elevated, irritable mood lasting longer than 1 week (or any duration if hospitalization is required)

28
Q

What are the symptoms of hypomania and mania

A

DIGFAST

29
Q

3 main drug sets used to treat bipolar

A

Lithium: Stabilize neurons
Anticonvulsants: Enhance GABA
Atypical antipsychotics: Inhibit excess dopamine

30
Q

What is kindling hypothesis

A

the more episodes that occur early in the illness, the more frequent and severe later episodes are likely to be.

31
Q

ECT and pregnancy

A

Safe

32
Q

ECT works for depression or mania

A

Both