mood disorders Flashcards
mood states
- differentiated based on severity and duration
- euthymia: the goal of treatment; living without mood disturbances and achieving baseline again
- feeling sad/upset/grief
- major depressive episode
- dysthymia
- hypomania: extroverted/energetic/intensely emotional people
- mania
polarity of mood states
- average length of time for the first major depressive episode is 9 months
- untreated MDE= 4-5 months
- untreated manic episode= 2-6 months but often noted well before then
major depressive episode criteria *
- 5 or more symptoms of the 9, during the same two-week period: depressed mood, significantly diminished interest/pleasure in all activities (anhedonia), significant weight loss or gain, insomnia/hypersomnia, psychomotor agitation/retardation, fatigue or loss of energy, feeling worthless/excessively guilty, diminished ability to think or concentrate, recurrent thoughts of death/suicide
- at least one of the symptoms have to be depressed mood or anhendonia
major depressive disorder criteria
- one or more MDE
- single episode or recurrent (more than one episode, needs to be at least 2 months symptom free between episodes)
- cannot be a normal response to a significant loss (can still be diagnosed with MDD)
- no history of mania/hypomania
- women are more likely than men
- mean age of onset is early pubery - early twentie
persistent depressive disorder (dysthymia) criteria
- depressed mood for most of the day, nearly every day, for 2 years
- additional symptoms (2 or more of the 6): poor appetite, insomnia/hypersomnia, low energy, low self-esteem, poor concentration, feelings of hopelessness
- incredibly chronic
- no history of mania/hypomania
- women are twice as likely as men
- mean age of onset is early adulthood
manic episode (mania)
- a week period of significantly elevated, expansive, or irritable mood and significantly increased goal-directed activity or energy
- can have psychosis features
- component of many mood disorders
- if the individual is hospitalized, then they do not need to experience the mania for the full 7 days*
mania criteria
- additional symptoms (need 3 of 7):
- inflated self-esteem or grandiosity
- decreased need for sleep
- more talkative than usual or pressure to keep talking
- flight of ideas (racing thoughts)
- distractibility
- increased goal-directed activity or psychomotor agitation (restless)
- excessive involvement in risky behaviours (buying sprees, gambling)
hypomania criteria
- 3-7 symptoms
- identical to a manic disorder, except: typically shorter in duration but must last at least 4 days, not severe enough to cause hospitalization*
- no significant impairment in daily functioning, no psychotic features
bipolar I disorder
- only one requirement, and it’s mania!
- MDE is not a requirement of BPD I but are very common in it
- highly recurrent, 90% of people who have an episode will have another
- 60% of people will then go on to have a MDE
- equal rates for men and women
- mean age of onset is 18
bipolar II disorder
- criteria: has had a hypomanic (low) episode, has had a MDE
- no history of mania
- equal rates for men and women
other BPD notes
- people BPD I have more hypOmanic episodes than people with BPD II
- people with BPD II will have more total episodes than people with BPD I
- main issues with treating BPD is that individuals enjoy mania
cyclothymic disorder
- 2 year period where individuals are cycling between the highs and lows of BPD
- numerous hypomanic SYMPTOMS, numerous depression SYMPTOMS
- between 15-50% of people will go on to develop BPD I or II
- equal rates for men and women (but women more likely to seek treatment)
- mean age of onset is similar to BPD, early adolescence and early adulthood
mood disorder specifiers
- psychotic features: hallucinations/delusions, rare but if present they may predict worse outcomes
- melancholic features: anhedonia, excessive guilt, severe somatic symptoms (weight loss, loss of libido)
- atypical features: overeating/sleeping but no anhedonia
- peripartum: just before or after death
- seasonal pattern: depression/mania associated with a particular season
- rapid cycling: experiencing four episodes of mania, hypomania, or MDE within 12 months
biological approaches to mood disorders (genetics)
- tends to run in families, especially in twins
- more recurrent forms of depression and BPD tend to be stronger in families
biological approaches to mood disorders (behavioural activation system)
- sensitivity to rewards and motivation
- linked to dopamine
- individuals can have a global reaction to activity happening in the environment (ie. something motivating or rewarding)
- positive emotions and hope
biological approaches to mood disorders (neurotransmitters)
- theory*
- low levels of serotonin
- allows NE and dopamine to range wildly
biological approaches to mood disorders (sleep)
- sleep disruptions may lead to depression or mania
mood disorder medications
- tricyclic antidepressants: increase the amount of NE and serotonin in the synaptic cleft, can be lethal if overdosed
- MAOIs: increase the amount of NE, serotonin and dopamine, lots of dietary precautions (no beer, red wine or cheese) and risks of severe reactions if mixed with other drugs
- SSRIs: increased amount of seretonin
- mood stabilizers: lithium (reduce frequency and intensity of manic episodes), anticonvulsants, prevents and threats manic episodes
mood disorder non-pharmaceutical methods (ECT)
- electroconvulsive therapy
- unilateral vs bilateral (unilateral has less side effects than bilateral but less effective)
- shock administered for less than a second, once every other day 6-10 times
- 50% respond
- relapse tends to be common, people go on medication after
- acutely suicidal or depressed with psychosis individuals will be directed straight to this
psychological approach to mood disorders (interpersonal psychotherapy)
- etiology: perceived stressful life event triggers onset, stressful relationships worsen the disorder, relationship problems significant factor for women
- for men, depression damages a relationship and for women, its the relationship that causes depression
interpersonal psychotherapy treatment of mood disorders
- resolve problems in current relationships and form new important relationships
- tends to be more effective than support groups/psychodynamic therapy/placebo
- 60-70% effective
psychological approach to mood disorders (beck’s CBT etiology)
- etiology: percieved stressful life event or automatic thoughts trigger onset
- lack of mastery (ability to accomplish much)
- numerous cognitive distortions (ie. overgeneralization, arbitrary inference [jumping to negative conclusions without evidence], catastrophizing)
psychological treatment to mood disorders (beck’s CBT)
- decrease the plausibility and strength of negative thoughts by: behavioural activation (helps people identify the smallest thing they can do, have them do it, and then they gain a sense of mastery to do greater things), identify dysfunctional thinking styles (may use tools like thought record), correct negative thoughts and substitute more realistic thoughts, challenge deeper held schemas
CBT treatments for bipolar disorder
- standard CBT for depression symptoms
- decreasing desire for mania
- increasing medical compliance
- find ways to make patient see pros of not being manic