Monoclonal Antibody Indications Flashcards

1
Q

Keliximab indication

A

Rheumatoid arthritis

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2
Q

Abciximab indication

A

Antithrombotic for PCI; prevention of MI

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3
Q

Alemtuzumab indication

A

Chronic lymphocytic leukemia

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4
Q

Apolizumab indication

A

Chronic lymphocytic leukemia

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5
Q

Basiliximab indication

A

Prevention of acute renal allograft rejection

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6
Q

Clenoliximab indication

A

Rheumatoid arthritis

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7
Q

Daclizumab indication

A

Prevention of acute renal allograft rejection

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8
Q

Edrecolomab indication

A

Adjuvant therapy for cancer

after colorectal surgery

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9
Q

Efalizumab indication

A

Treatment of severe plaque psoriasis

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10
Q

Enlimomab indication

A

Burns; stroke; prevention of acute rejection in renal transplant

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11
Q

Epratuzumab indication

A

Non-Hodgkin’s lymphoma

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12
Q

Gemtuzumab indication

A

CD33

positive acute myelogenous leukemia

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13
Q

Infliximab indication

A

Rheumatoid arthritis; ankylosing spondylitis; Crohn’s disease

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14
Q

Inolimomab indication

A

Prevention of graft rejection

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15
Q

Keliximab indication

A

Rheumatoid arthritis

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16
Q

Muromonab indication

A

Prevention of acute renal allograft rejection

17
Q

Natalizumab indication

A

Acute relapse in multiple sclerosis; Crohn’s disease

18
Q

Ocrelizumab (Ocrevus) indication

A

Multiple Sclerosis

19
Q

Odulimomab indication

A

Prevention of ischemic renal damage during kidney transplantation

20
Q

Omalizumab indication

A

Prevention of allergic asthma and seasonal rhinitis

21
Q

Palivizumab indication

A

Prevention of respiratory syncytial virus infection

22
Q

Visilizumab indication

A

Treatment of glucocorticoid-refractory acute graft-versus-host disease

23
Q

Rituximab, ofatumumab, obinutuzumab
indication

A

Hematologic malignancies

24
Q

Trastuzumab, Amivantamab, Nivolumab, Pembrolizumab indication

A

Solid tumors

25
Q

Adalimumab, Tocilizumab, Sarilumab indication

A

Autoimmune disorders

26
Q

Evolucumab and Alirocumab indication

A

Hypercholesterolemia

27
Q

Omalizumab indication

A

Asthma

28
Q

Denosumab indication

A

Osteoporosis

29
Q

Adalimumab, certolizumab pegol indication

A

Inflammatory bowel disease

30
Q

Atoltivimab+maftivimab+odesivimab (Inmazeb), ansuvimab (Ebanga) indication

A

Ebola-specific therapies

31
Q

Bezlotoxumab indication

A

Clostridioides difficile infection in adults

32
Q

Idarucizumab (Praxbind) indication

A

Dabigatran reversal

33
Q

Tixagevimab/cilgavimab (Evusheld) indication

A

COVID infection prevention in immunocompromised individuals who may not mount an adequate immune response to COVID-19 vaccination

34
Q

Sotrovimab (Xeundy) indication

A

COVID. IV administration