Monoclonal Antibodies - B3 Flashcards
What is an antigen?
An antigen is a toxin which induces an immune response in the body, such as the production of
antibodies
Monoclonal antibodies are produced from a single (_____) of cells.
The antibodies are specific to one (binding) site on one (_______) antigen and so are able to target a specific chemical or specific cells in the body.
(_____) lymphocytes are stimulated to produce a particular antibody.
The lymphocytes are combined with a particular kind of (______) cell to make a cell called a hybridoma cell.
The (_________) cell produces the antibody.
Monoclonal antibodies are produced from a single (clone) of cells.
The antibodies are specific to one (binding) site on one (protein) antigen and so are able to target a specific chemical or specific cells in the body.
(Mouse) lymphocytes are stimulated to produce a particular antibody.
The lymphocytes are combined with a particular kind of (tumour) cell to make a cell called a hybridoma cell.
The (hybridoma) cell produces the antibody.
What is a monoclonal antibody?
Monoclonal antibodies are antibodies that are made by identical immune cells that are all clones of a unique parent cell.
Name three things monoclonal antibodies are used for.
Diagnosis in pregnancy tests.
In research to identify or locate or identify specific molecules in a cell or tissue by binding to them with a fluorescent dye.
For treating cancer, the monoclonal antibody can be bound to a radioactive substance, a toxic drug or a chemical which stops cells growing and dividing.
A major problem with using monoclonal antibodies to treat cancerous cells is that they produce a lot of unexpected side effects.
