Monoclonal Antibodies Flashcards
1
Q
What are monoclonal antibodies?
A
Antibodies produced from a single clone of B cells, all identical and specific to one antigen.
2
Q
How are monoclonal antibodies made (Short version) ?
A
By fusing a B cell with a tumor cell to create a hybridoma that produces the desired antibody.
3
Q
True or False: Monoclonal antibodies are all identical and specific to one antigen.
A
True
4
Q
Fill in the blank: Monoclonal antibodies are produced from a single clone of _____ cells.
A
B
5
Q
True or False: Monoclonal antibodies can only target cancer cells.
A
False
6
Q
What is the significance of monoclonal antibodies in infectious disease research?
A
They can identify and neutralize pathogens like viruses or bacteria.
7
Q
How do you make a monoclonal antibody ?
A
- Inject antigen into the mouse so that the antibody you will produce will be specific to the disease
- Then extract the lymphocyte from the mouse
- Fuse the lymphocyte with a tumour cell
- Then that will create the hybridoma
- Then you can clone the hybridoma antibodies produced
