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Molecules > Molecules > Flashcards

Molecules Flashcards

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Organic Chemistry 101 flashcards
1
Q

Pervenche de Madagascar

A

Catharentus roseus

vinblastine et vincristine par extraction = anticancéreux

vindesine et vinorelbine par hemisynthese = anticancéreux

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2
Q

If du pacifique

A

Taxus brevifolia

Taxol = Anticancéreux

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3
Q

If européen

A

Taxus baccata

Taxol et taxotere par hemisynthese = Anticancéreux

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4
Q

Pavot somnifère

A

Papaver somniferum
Opium Morphine et thébaine = antidouleurs par extraction
Codéine = antitussif par extraction

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5
Q

Armoise annuelle

A

Athemisia annua
Arthemisinine = antipalu par extraction
Artheether et arthemether = antipalu par hemisynthese

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6
Q

Perce neige

A

Galanthus Sp

Galanthamine = antialzeihmer (alcaloïde) synthèse totale possible

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7
Q

Saules

A

Salix

Acide salicylique = antidouleur par extraction

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8
Q

Quinquina

A 
Plante
Cinchona pubescens 
Quinine = antipaludéen
Quinidine = anti arythmique 
Nbrx derives d’hemisyntheses
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9
Q

Caféine

A

Stimulant

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10
Q

Pancréas de bœuf ou porc

A

Insuline et glucagon (hyper/hypo glycémie)

Ajd biotechs

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11
Q

Extrait d’intestin de porc ou de bœuf

A

Héparine = anticoagulant

Ajd biotechs

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12
Q

Cadavre humain (hypophise)

A

Somatotrophine = hormone de croissance (ajd biotechs)

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13
Q

Venin de serpent

A

Anticoagulant
Inhibiteur enzymatique
Analogue du glucagon

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14
Q

Ergot de seigle

A

Claviceps purpurea
Ergotamine = vasoconstricteur et anti migraineux par extraction
Nbrx dérives d’hemisynthese

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15
Q

Pénicillium citrinum

A

Extraction de mévastatine = hypocholesterolemiant en inhibant HMG-CoA
Nbrx dérives d’hemisynthese

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16
Q

Aspergillus terreus

A

Extraction de lovastatine = hypocholesterolemiant en inhibant HMG-CoA

17
Q

Nouvelle molécule d’origines microbiennes

A

Anticancéreux par extraction

18
Q

Algues brunes

A

Laminaria sp

Extraction d’Alginates (polysaccarides) = gastro-entérologie ou gélifiant,épaississant,liant en agroalimentaire

19
Q

Algues rouges

A

Chondrus crispus

Extraction de carraghenanes (polysaccarides) gastro entéro, gélifiant épaississant et liant

20
Q

Mycromycete marin

A

Cephalosporium
Hemisynthese
Cephalosporine = antibactérien

21
Q

Éponge marine

A 
Cryptothetia crypta
Synthèse totale 
Arabinoside = anticancéreux 
Cytarabine = antitumoral 
Vidarabine = antiviral
22
Q

Ascidie

A

Ecteinascidia

Extraction ecteinsacidine-743 et trabectedine = antitumoral

23
Q

Cône

A

Conus magnus

Extraction de conotoxines = antidouleur
Synthèse du ziconotide lui aussi antidouleur

Et autres toxines

Molecules (1 decks)

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