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Immune segundo parcial > Moléculas de adhesión celular > Flashcards

Moléculas de adhesión celular Flashcards

1
Q

Las moléculas de adhesión celular permiten que se lleve a cabo la adherencia a

A

Otras células y la matriz extracelular

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2
Q

Se involucran en las siguientes actividades

A

Generación de RI
Fase efectora de RI
Migration celular
Recirculación de linfocitos
Inflamación
Coagulación/trombosis
Metastasis

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3
Q

Selectina L

A

O CD62L Leucocitos

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4
Q

Selectina E

A

O CD62E Endotelio activado

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5
Q

Selectina P

A

O CD62P Plaquetas (gránulos A), Endotelio (corpúsculos de Weibel-palade)

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6
Q

Ligandos o contra-receptores de Endotelio, selectina L

A

GlyCAM (HEV)
MadCAM-1 (HEV-P. Peyer)
Nepmucin (HEV)
CD34

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7
Q

Ligandos o contra-receptores de Endotelio, Selectina P

A

PSGL-1 (CD162)

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8
Q

Ligandos o contra-receptores de Leucocitos, Selectina E

A

ESL-1
CLA
CD44

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9
Q

Ligandos o contra-receptores de Leucocitos, Selectina P

A

PSGL-1

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10
Q

CD2 interacciona con (Igs)

A

LFA-3 (CD58) que se expresa en CPA y linfocitos

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11
Q

ICAM-1-2 y 3 interaccionan con (Igs)

A

Integrinas B2

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12
Q

Donde se expresa ICAM -1 (CD54) (Igs)

A

C. endoteliales activadas, células epiteliales, MO y linfocitos

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13
Q

Donde se expresa ICAM-2 (CD102) (IGs)

A

Leucocitos y células endoteliales

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14
Q

Donde se expresa ICAM-3 (CD50) (Igs)

A

Linfocitos

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15
Q

Con quien interacciona PECAM-1 (CD31) (Igs)

A

Lleva a cabo una interacción homotípica en células endoteliales y leucocitos

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16
Q

Con quien interacciona VCAM-1 (CD106)

A

VLA-4 en células endoteliales activadas

17
Q

Con quien interacciona JAM-1 (CD321)

A

JAM-1 e integrinas B2 en Leucocitos y células endoteliales

18
Q

Con quien interacciona JAM-2 (CD322)

A

JAM-3 e integrinas B1 en células endoteliales

19
Q

Con quien interacciona JAM-3

A

JAM-2 y 3 en leucocitos y células endoteliales

Immune segundo parcial (4 decks)

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