Molecular Events And Molecular Biology Flashcards
Published a paper on mutations
1901- Hugo de vries
Demonstrated that chromosomes exist in pairs that are structurally similar.
1902- Walter Stanborough Suton
Proved that sperm and egg cells have
one of each pair of chromosomes.
1903 - Sutton
Genes are located in chromosome;
Discovered X and Y chromosomes, sex-
linked traits and crossing -over.
1908 - THOMAS HUNT MORGAN
W/ ALFRED H. STURTEVANT
Poposed that each portion of a
chromosome that controls a phenotype be
called a “gene”.
1909 - Wilhelm Ludvig Johannsen
Began constructing a chromosome
map for Drisophila
1913 - Alfred Henry Sturtevant
EXPERIMENTED WITH DROSOPHILA TO
CREATE MORE MUTANT FLIES.
1919 - JOSPEH MULLER
Discovered that genes control the
production of enzymes.
1941 - George W. Beadle &
Edward L. Tatum
Announced that is the
substance responsible for heredity.
- 1944
- Oswald T. Avery
- DNA alone
Made a molecule and
proved that genes determine heredity.
- 1952
- FRANCIS H.C CRICK
AND JAMES D WATSON - model of the DNA
discover starting a new branch of
science
- 1950’s
- Maurice Wilkins &
Rosalind Franklin - chemical
structure of DNA
Produced DNA in a test tube
- 1957
- Arthur Kornberg
GENETIC CODE WAS DISCOVERED; ENABLE
SCIETIST TO PREDICT CHARACTERISTICS BY
STUDYING DNA. THIS LEADS TO AND .
- 1966
- GENETIC ENGINEERING; GENETIC COUNSELING
Produced the first recombinant DNA
molecule.
- 1972
- Paul Berg
the first recombinant DNA drug
approved by the FDA - .
- 1982
- genetically engineered insulin for diabetics.
AWARDED THE NOBEL PRIZE FOR THE
DISCOVERY THAT GENES ARE ABLE TO
CHANGE POSITION ON .
- 1983
- BARBARA MCCLINTOCK
- CHROMOSOMES
An international team of scietist began to
project to map the human genome.
1988
first crime conviction based on DNA
fingerprinting
Late 1980’s
WAS USED ON PATIENTS
FOR THE FIRST TIME.
- 1990
- GENE THERAPY
DNA TESTING IN FORENSICS CASES
GAINS FAME IN THE O.J. SIMPSON TRIAL
CASE.
1995
THE FDA APPROVED THE FIRST
GENETICALLY ENGINEERED FOOD -
- ENGINEERED FOR
BETTER FLAVOR AND SHELF LIFE.
-1994
- FLAVRSAVR TOMATOES
- THE FIRST ADULT
ANIMAL CLONE
-1997
- DOLLY THE SHEEP
generations of mice were cloned
from the nuclei of an adult Eight
identical calves were cloned. The
rough draft of the human genome
map was produced.
- 1998
- Three
- rough draft
was credited for his primary thoughts of evolution.
Anaximander
did not directly aid in the progress of biological thinking, but many of his students went on to influence the progression of biological studies in the field of .
- Plato
- classification
credited as being the Father of
Atomic Theory which connects directly to biology.
The Atomists (Democritus)
was known for his experimental approach and
numerous dissections.
Aristotle
downfall of scietific thoughts. usually
attributted to the Christian Church and the power shift to the “barbaric” tribes.
The Dark Ages
advancemento of anatomical thought following the
Dark Ages, such as discovering the circulation of blood.
Leonardo da Vinci, Rene Descartes, and Willian Harvey
coined the term “cell” after viewing slices
of cork though a microscope.
Robert Hooke
coined the term “cell” after viewing slices of cork through a microscope.
Robert Hooke
“the cell is the fundamental element in
the structure of living bodies. “
Rene Dutrochet
animals are composed of cells.
Theodore Schwann
all plant tissues are composed of cells.
Matthias Schleiden
“every cell comes from a cell.”
Rudolf Virchow
Cell Theory
Schleiden and Schwann -
a. All life forms are made from one or more cells.
b. Cells only arise fron pre-exiting cellls.
c. The cell is the smallest form of life.
1655 - ROBERT HOOKE
-Designed his own microscope and
discovered that matter is made up of “cells”.
-Wrote .
- 1655
- ROBERT HOOKE
- Micrographia
-Proposed a general cell theory.
- 1975
- Caspar Friedrich
Wolf
discovered that “the cell is the
fundamental element in the structure of
living bodies, forming both animals and
plants through “.
- 1842
- Rene Dutrochet
- jaxtaposition
Created connection between biology and
medicine, prompting the connective
thinking of his students, such as .
- 1824
- JOHANNES MULLES
- Theodore Schwann
Plants are made up of cells.
- 1838
- Mattias J. Schleiden
Published cell theory and applied to
animals.
- 1839
- Theodore Schwann
BEGAN EXPERIMENTS WITH PEA PLANTS
LATER BECAME KNOWN AS THE “ “
- 1857
- GREGOR JOHANN MENDEL
- FATHER OF GENETICS
Published “On the Origin of species”,
explaining units of in species.
- 1859
- Charles Darwin
- heredity and variations
Announced his theories of heredity
known as .
- 1869
- Mendel
- Mendel’s Laws
CLAIMS THAT HEREDITY ALONE IS
RESPONSIBLE FOR A PERSON’S CHARACTER
TRAITS, PUBLISHED IN HIS BOOK, .
- 1869
- SIR FRANCIS GALTON
- HEREDITARY GENUIS
Used dyes to stain cells; discovered rods he
called “ “.
- 1882
- Walther Fleming
- chromosomes
created the term “ “ while
experimenting with .
- 1886
- Hugo de Vries
- mutation; primroses
Discovered that all organisms of the same
species have the same number of
chromosomes.
- 1887
- EDOUARD VAN BENEDEM
1892 - August Weismann
Published an essay on heredity. Proposed
that heredity was transmitted by a
substance with a “ “.
- 1892
- August Weismann
- chemical and molecular
constitution
Published a paper that includes laws of inheritance.
- 1900
- de Vries; Karl Erich
Correns; Erich Tschermak