Module 8 Flashcards
What is homeostasis
maintenance of an internal environment despite changes in the external environment.
Explain what a negative feedback loop is with steps
A system where change is detected and counteracted to return body to its optimal state.
- A change occurs
- The change is detected by an appropriate receptor
- Receptor sends a signal to the control centre
- Control centre sends a signal to an appropriate effector
- Effector responds to the signal.
Explain the negative feedback loop for temperature regulation
Heat
1. Stimulus: body temeprature rises over 37 degress
2. Receptor: thermoreceptor detects change, sent to hypothalamus
3. Effector
* Vasodilation: Capillaries fill with warm blood so more heat can radiate from the skin’s surface
* Sweating: sweat glands activate and secrete perspiration which is vaporised by heat
Cold
1. Stimulus: body temeprature drops below 37 degress
2. Receptor: thermoreceptor detects change, sent to hypothalamus
3. Effector
* Vasoconstriction: blood is diverted from capillaries to minimise heat loss from skin
* Shivering: muscle contractions producing heat
Explain the negative feedback loop for blood glucose level regulation
Hyperglycaemia
1. Stimulus: BGL rises above 4-6mmol/L
2. Receptor: Beta cells in pancreas detects change
3. Effector: Hormone inslulin is released, increasing rate of glucose taken up by body cells and causes liver to store sugar as glycogen
Hypoglycaemia
1. Stimulus: BGL falls above 4-6mmol/L
2. Receptor: Alpha cells detect change
3. Effector: Hormone glucagon is released causing the liver to break down glycogen and release glucose in blood
Explain the behavioural adaptations in endotherms that assist in maintaining homeostasis
- Licking (cats) heat evaporates through saliva
- Panting (dogs) expells hot air
- Seaking shade / sun (cats) heat or cold radiation
Explain the structural adaptations in endotherms that assist in maintaining homeostasis
- Blubber (whale) insulates from cold water
- fur (polar bear) Insulates skin from cold air
- SA:V ratio - higher for hot and lower for cold () heat easily loss or kept
Explain the physiological adaptations in endotherms that assist in maintaining homeostasis
- Hibernation (bears) inhabit inhospitable environments
- Sweating (horses) expelling heat through vapour
- Vasodilation (humans) more heat can radiate from skin
Explain the internal coordination system of neural pathways that allow homeostasis to be maintained
Thr nervous system uses electrochemical impulses in nerves to relay information such as stimulus reception, interpretation and generation of an appropriate response
* Sensory neurons receive information and send to CNS
* Motor neurons from CNS sends a response to effector organs
E.g. thermoreceptors detect hot surface -> sensory neurons send message to CNS -> motor neurons make muscle move
Explain the internal coordination system of hormones that allow homeostasis to be maintained
The endocrine system consists of glands which secrete hormones into the bloodstream and travel to targeted cells, triggering a specific response.
E.g. Beta cells detect high BGL -> pancreas secreates insulin -> liver absorbs abd stores glucose
Explain the homeostasis mechanisms in plants
- Stomata: opens early morning and evening in cool temperature for photosynthesis but closes during intense heat and sunlight, preventing dehydration
- Thick and waxy cuticle: insulates water from excess sunlight, decreasing evaporation rate
- Shiny leaves: reflects sunlight, reducing internal temperature and rate of transpiration
Explain the causes and effects of genetic non-infectious diseases in humans
Cystic Fibrosis
Cause: Mutation involving deletion of three base (CCT) in CF gene.
Effect: Effects cells responsible for secretion of mucus, sweat and digestive fluids. Individuals may have problems with breathing or performing exercise.
Explain the causes and effects of non-infectious diseases caused by environmental exposure in humans
Skin cancer
Cause: Thymine dimer – bonding of thymine bases on same DNA strand.
Effect: Discoloured area of skin, yellow discolouration. Dilation of blood vessels. Destruction of elastic tissue.
Explain the causes and effects of non-infectious nutritional diseases in humans
Iron deficiency
Cause: Insufficient intake of iron
Effect: Tiredness and muscle weakness, pale skin, headache, dizziness, light- headedness
Define incidence, prevalence and mortality rate
Incidence: number of new cases per 100,000 in a population
prevalence: total number of cases per 100,000 in a population
Mortality rate: number of deaths
Analyse the treatment/management for further reasech of a disease caused by environmental exposure
Cancer
* Chemotherapy: drugs eliminating cancer cells during mitosis
* Surgery: localised melanoma cells cut out
* Monoclonal antibodies: injection of antibodies specific to particular antigen on cancer cells