Module 6 Flashcards

1
Q

first-third order sensory neurons

A

first order: sensory receptor, receives sensation
second order: neuron between first and third
third order: takes second order neuron and transmitts signal to brain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

how is the location of a stimulation determined?

A

post central gyrus has a body map that maps onto what region of the cortex is activated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what kind of information is transmitted in a sensory receptor?

A

modality, location, intensity, and duration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what does the somatic sensory system detect?

A

external forces on the body, internal changes, and information about the position of limbs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

where are somatic sensory receptors?

A

skin, muscles, tendons, joints, viscera

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

how is the amount of firing determined by senation?

A

more stretch leads to more action potentials (rate of firing is directly proportional to the magnitude of depolarization)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Ia, II afferent axons

A

fast conductance, large diameter, lots of myelin
use: proprioception, muscle spindle (balance)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Ab afferent axon

A

second most myelin
use: touch, merkel, meissner, pacinian, ruffini cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Ag afferent axons

A

slowish conductance
Use: pain and temperature

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

C afferent axons

A

no myelin, slow conductance
Use: pain, temperature, itch

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what is two point discrimination?

A

the minimum distance to perceive two stimuli as distinct (smaller is better perception)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what does it mean for a receptor to be slow to adapt?

A

it keeps firing when there is a continuous stimuli

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what is the mechanosensory pathway for?

A

touch, vibration, pressure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

meissner sensory receptors

A

Detect: movement across skin, slippage of textured objects
adapting: rapidly

corpuscle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

merkel sensory receptors

A

detect: edges, points, shapes, texture
adapting: slow
*low two point discrimination in fingertips

also detects pain, temp, no capsulation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

ruffini sensory receptors

A

detect: skin strech, hand shape
adapting: slow

corpuscle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

pacinian sensory receptors

A

detect: vibrations, tool use
adapting: rapidly

corpuscle

17
Q

conveying mechanosensory info to cortex from periphery afferent pathways

A
  1. two pathways (upper and lower body, cudeate and gracile), end at dorsal column nuclei of medulla
  2. jump over to other side, end at VPL nucleus of thalamus
  3. end at primary somatosensory cortex (S1)
18
Q

mechanosensory info to cortex from face

A
  1. trigeminal ganlion
  2. projects to thalamus
  3. VPM nucleus of thalamus
19
Q

what is the procioceptive pathway for?

A

position of limbs, body parts in space

20
Q

group 1A afferent axons

A

detect limb movement, muscle changing length

21
Q

group II afferent axons

A

detect static position (moving and stretching)

22
Q

axonal 1B afferent

A

measures tendon tension

23
Q

where do procioceptive pathways map to?

A

reflexes to cerebellum and cortex, everything else to dorsal column nuclei

24
piezo
piezo 2 is usually more important in PNS structure: two wings, if push down on plates or pull membrane, will open, more than 30 TM regions use: mechanosensory and proprioceptive pathway without: don't respond to pressure, uncoordinated body movements
25
what does the anterolateral pathway detect?
temperature, pain, and non-discriminative touch
26
when do nociceptor's respond?
when the temperature can lead to tissue damage (responds to higher temperatures than thermoceptors)
27
Ag axons in anterolateral pathway?
for cool temperatures & sharp pain project to laminae I and V
28
C axons in anterolateral pathway?
for warm temperatures & burning pain project to laminae I and II
29
pathway of anterolateral pathway from peripheral axons
1. DRG axons terminate at dorsal horn of spinal cord, immediately synapse w 2nd order neurons 2. jump sides, descend spinal cord to VPL nucleus of thalamus 3. project to S1
30
pathway of anterolateral pathway from face
1. to trigeminal nerve and terminate in SNTC 2. jump sides VPM of thalamus
31
noxious stimuli
hot/ cold, tissue damaging
32
receptors for temp
TRP
33
receptors for chemicals
TRP, ASIC
34
receptors for mechanical stimulation
TRP, ASIC, Piezo's
35
TRP family
chili: TRPV1 and TRPV2 nociceptors: TRPV1
36
how does pruciception progress?
scratch --> prutigens (histamines and drugs) ex. opioids lead to itch
37
how does pain and itch override?
pain overrides itch (ex. slapping a mosquito bite)
38
how to control mild pain?
target peripheral inflammation (progastines)
39
how to control moderate to severe pain?
target nervous system
40
gate theory of pain
activation of mechanoreceptors modulates transmission of nociceptive information (why counter pressure works)