Module 5.3 - H and Na gradient drive membrane transport of nts Flashcards
1
Q
Where are neurotransmitters synthesized?
A
In cytoplasm
2
Q
What happens following nt synthesis?
A
Actively transported into presynaptic vesicles
3
Q
What is the process following neurotransmitter secretion where the nt is taken back into cells?
A
Re-uptake
4
Q
What is the purpose of re-uptake?
A
Helps stop synaptic signals
Replenishes/recycles transmitters
5
Q
How does nt transport work?
A
Vesicular transporters use H+ gradients to move transmitters into the lumen of synaptic vesicles
6
Q
How is the H+ gradient used for transmitter transport established?
A
Vacuolar-type H ATPases consume ATP to concentration H+ ions in vesicles
