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Samplex Module 5 > Module 5 - Mock Boards > Flashcards

Module 5 - Mock Boards Flashcards

1
Q

This law states that at constant pressure, the volume of a given quantity of gas varies directly with the absolute temperature.
a. Dalton’s law
b. Charles’ Law
c. Raoult’s Law
d. Henry’s Law

A

b. Charles’ Law

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2
Q

One gram of a solid drug sample required 473 mL of water to completely dissolve. Describe its solubility in water.
a. Freely soluble
b. Soluble
c. Sparingly soluble
d. Slightly soluble

A

d. Slightly soluble 100-1000

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3
Q

Long-term stability studies use zero-order reaction. This means that:
a. The rate of reaction is independent of the concentrations of the reactants
b. The rate of reaction is dependent of the concentrations of the reactants
c. The rate of reaction is proportional to
the square of one reactant or the
product
d. The rate of reaction cannot be
determined

A

a. The rate of reaction is independent of the concentrations of the reactants

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4
Q

This is a colloidal dispersion of liquid in gas.
a. Xerogel
b. Suspension
c. Aerosol
d. magma

A

c. Aerosol

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5
Q

This type of instability manifests as the
upward movement of dispersed droplets.
a. Flocculation
b. Creaming
c. Sedimentation
d. agglomeration

A

b. Creaming

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6
Q

This is the official method of particle size determination according to the USP.
a. Microscopic determination
b. Sieving
c. Sedimentation
d. Volume measurement

A

b. Sieving

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7
Q

These are powder particles that have been aggregated to form a larger particle with 0.2 to 4-mm diameter.
a. Granules
b. Nanoparticles
c. Liposomes
d. Pellets

A

a. Granules

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8
Q

HLB is a measure of:
a. Hydrogen and lithium content of a substance
b. Hydrolytic lyophilic property of colloids
c. Hydrophilic and lipophilic tendency of
surfactants
d. Hydrophobic and lipophilic tendency of
oils

A

c. Hydrophilic and lipophilic tendency of
surfactants

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9
Q

Which of the following is the effect of hypotonic solutions on human blood cells?
a. Division
b. Hemolysis
c. Crenation
d. No effect

A

b. Hemolysis

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10
Q

Which of the following is the effect of hypotonic solutions on human blood cells?
a. Division
b. Hemolysis
c. Crenation
d. No effect

A

b. Hemolysis

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11
Q

Which of the following best describes an isotonic solution?
a. It has the same pH as the blood
b. It has the same salt content and fluid
pressure as the blood
c. It has the same sodium content as the
blood
d. It has the same fluid pressure as the
blood

A

b. It has the same salt content and fluid
pressure as the blood

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12
Q

This excipient is most widely used as a
diluent
a. Lactose
b. Croscarmellose
c. Stearic acid
d. Mannitol

A

a. Lactose

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13
Q

How many mg of NaCl should be added to the following formulation to make it isotonic? (E Cocaine HCl is 0.16)

Cocaine HCl 2.0%
NaCl q.s
Purified water 30.0mL

a. 48mg
b. 174 mg
c. 222 mg
d. 96mg

A

b. 174 mg

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14
Q

This method is employed for blending of
potent substances.
a. Spatulation
b. Sifting
c. Geometric dilution
d. Pulverization with intervention

A

c. Geometric dilution

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15
Q

This hardness tester for tablets uses hand pliers.
a. Stokes-Monsanto
b. Schlueniger
c. Pfizer
d. Strong-Cobb

A

c. Pfizer

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16
Q

Which is a property of a solution that depends on the number of particles of solute dissolved in the solution?
a. pH
b. Temperature
c. Colligative
d. Surface tension

A

c. Colligative

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17
Q

This is a class of surfactant that contains
both anion and cation.
a. Amphoteric
b. Lipophilic sorbitan esters
c. Non-ionic surfactants
d. Hydrophilic-polyoxyethylene sorbitan
esters

A

a. Amphoteric

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18
Q

Which of the following will exhibit a faster rate of dissolution?
a. Crystalline
b. Hydrate
c. Amorphous
d. Solvate

A

c. Amorphous

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19
Q

Which is a unit for area?
a. cm/s
b. g/cm3
c. cm2
d. dynes-cm2

A

c. cm2

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20
Q

Which dimensions are measured for
surface tension?
a. Force and length
b. Pressure and area
c. Mass and time
d. Mass and area

A

a. Force and length

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21
Q

Which is the change in state from solid to vapor without passing the liquid state?
a. Deposition
b. Sublimation
c. Evaporation
d. Condensation

A

b. Sublimation

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22
Q

How would you prepare a 500.0 mL solution of 20.0% w/v solution of Na2CO3 (MW: 106g/mole)
a. 100.0 g Na2CO3 add 500 mL distilled water
b. 106.0 g Na2CO3, q add 500 mL distilled water
c. 106.0 g Na2CO3, qs.ad distilled water to make 500.0 mL
d. 100.0 g Na2CO3, qs.ad distilled water to make 500.0 mL

A

d. 100.0 g Na2CO3, qs.ad distilled water to make 500.0 mL

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23
Q

Calculate the %w.v of 1.0 M NaOH (MW NaOH = 40g/mole)
a. 0.0025%
b. 4.0%
c. 1.0%
d. 0.5%

A

b. 4.0%

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24
Q

This law gives the relationship between the total pressure in a mixture of gases and the partial pressure of the individual gases
a. Dalton’s law
b. Charles’ Law
c. Raoult’s Law
d. Henry’s Law

A

a. Dalton’s law

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25
Q

This is used to measure the ratio of the velocity of light in air to its velocity in that material under like conditions.
a. Pycnometer
b. Stalagmometer
c. Abbe refractometer
d. Ostwald viscometer

A

c. Abbe refractometer

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26
Q

Calculate the pH of a salicylic acid solution if the pKa is 3.0 and the ratio of ionized to non-ionized species 0.1:1.
a. 4.0
b. 2.0
c. 13.0
d. 3.1

A

b. 2.0

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27
Q

Which of the following will exhibit a faster rate of dissolution?
a. Weakly basic drug in the intestine
b. Weakly acidic drug in the intestine
c. Weakly acidic drug in the stomach
d. None of the choices

A

b. Weakly acidic drug in the intestine

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28
Q

What is the millimoles of CaCO3 if 0.2433 g was dissolved in 50.0 mL distilled water? (MW: CaCO3 = 100 g/mol)
a. 2.43 millimoles
b. 48.7 millimoles
c. 0.243 millimoles
d. 4.87 millimoles

A

a. 2.43 millimoles

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29
Q

Bulk powders directed against body cavities for cleansing purposes
a. Triturations
b. Insufflations
c. Dusting powders
d. chartulae

A

b. Insufflations

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30
Q

This is added in the formulation for easy ejection of tablets from the punches and dies of the tableting machine.
a. Glidant
b. Surfactant
c. Lubricant
d. Diluent

A

c. Lubricant

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31
Q

Type of paper that can be used for efflorescent, deliquescent, and hygroscopic material due to its waterproof property
a. White bond paper
b. Glassine paper
c. Vegetable parchment
d. Waxed paper

A

d. Waxed paper

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32
Q

Container that is impervious to air:
a. Tight
b. Hermetic
c. Well-closed
d. Single-unit

A

b. Hermetic

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33
Q

An economical means of providing presentation, protection, identification, information, containment, convenience, and compliance for a product during storage, carriage, display, and use until such time as the product is used or administered:
a. Labelling
b. Packaging
c. Inserts
d. Transport box

A

b. Packaging

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34
Q

A water-soluble lubricant:
a. Mg stearate
b. Stearic acid
c. Talc
d. L-leucine

A

d. L-leucine

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35
Q

The partial or complete separation of the top or bottom of a tablet from the main body.
a. Lamination
b. Capping
c. Chipping
d. picking

A

b. Capping

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36
Q

Edible packages made from gelatin or other suitable material which are filled with medicines to produce unit dosages, mainly for oral use
a. Tablets
b. Suspension
c. Solution
d. capsules

A

d. capsules

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37
Q

Autoclave is an example of:
a. Dry heat sterilization
b. Moist heat sterilization
c. Chemical sterilization
d. None of the above

A

b. Moist heat sterilization

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38
Q

These are pharmaceuticals:
A. Parenterals
B. Solutions
C. Injections
D. Douches

A

A. Parenterals

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39
Q

Which of the following is a single-unit container?
a. Ampule
b. Vial
c. Medicine Bottle
d. All of the above

A

a. Ampule

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40
Q

Which of the following is a pair of pharmaceutical alternatives?
a. Ibuprofen tablet and naproxen tablet
b. Ampicillin suspension and ampicillin
capsules
c. Cimetidine and ranitidine
d. All of the above

A

b. Ampicillin suspension and ampicillin
capsules

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41
Q

Weight increase that can be expected after sugar coating of tablets:
a. 10-20%
b. 30-50%
c. 20-30%
d. 50-60

A

b. 30-50%

42
Q

Weight increase that can be expected after sugar coating of tablets:
a. 2-3%
b. 20-30%
c. 4-5%
d. 40-50%

A

d. 40-50%

43
Q

The following dosage forms possess a
shake well label, EXCEPT:
a. Magma
b. Lotion
c. Syrup
d. Suspension

A

c. Syrup

44
Q

The process in which primary powder particles are made to adhere to form larger, multi-particle entities.
a. Granulation
b. Flocculation
c. Agglomeration
d. Suspension

A

a. Granulation

45
Q

Which of the following will form a chelate with tetracycline?
a. Calcium in milk
b. Aluminum hydroxide
c. Magnesium hydroxide
d. All of the choices

A

d. All of the choices

46
Q

Which of the following will happen when you add suspending agents to a formulation?
a. Viscosity will increase
b. Particles will settle rapidly
c. Particles will agglomerate
d. A homogenous mixture will form

A

a. Viscosity will increase

47
Q

This is defined in the USP as “that state in which any residue of the tablet, except fragments of insoluble coating, remaining on the screen of the test apparatus in the soft mass have no palpably firm core.”
a. Complete disintegration
b. Complete dissolution
c. Complete absorption
d. Complete liberation

A

a. Complete disintegration

48
Q

Added to the tablet formulation to improve the flow properties of a dry powder blend before it is compressed:
a. Glidant
b. Surfactant
c. Lubricant
d. Diluent

A

a. Glidant

49
Q

Coating that protects the tablet from the acidic stomach pH:
a. Film coating
b. Sugar coating
c. Enteric coating
d. All of the above

A

c. Enteric coating

50
Q

Which of the following will be absorbed into the circulation the fastest?
a. Solution
b. Suspension
c. Capsule
d. Tablet

A

a. Solution

51
Q

This dosage form releases the active drug at a time other than immediately after the administration at a desired site in the GI tract
a. Effervescent tablet
b. Sublingual tablet
c. Buccal tablet
d. Delayed-release tablet

A

d. Delayed-release tablet

52
Q

A heterogenous mixture of an immiscible
liquid on another liquid
a. Solution
b. Ointment
c. Suspension
d. emulsion

A

d. emulsion

53
Q

What is the correct order of the steps involved in sugar-coating?
a. Subcoating → waterproofing and sealing → smoothing and final rounding → finish and coloring coats → imprinting → polishing
b. Subcoating → smoothing and sealing → final rounding → finish and coloring → polishing → imprinting
c. Waterproofing and sealing → smoothing and final rounding → subcoating → polishing → finish and coloring coats → imprinting
d. Waterproofing and sealing → subcoating → smoothing and final rounding → finish and coloring coats → imprinting → polishing

A

d. Waterproofing and sealing → subcoating → smoothing and final rounding → finish and coloring coats → imprinting → polishing

54
Q

The process in which drug molecules
interact with water molecule to yield breakdown product
a. Hydrolysis
b. Oxidation
c. Reduction
d. dehydration

A

a. Hydrolysis

55
Q

Filed to protect the rights and safety of the subjects and to achieve the stated objectives in the investigational plan:
a. Investigational new drug
b. New drug application
c. Abbreviated new drug application
d. Abbreviated investigational new drug

A

a. Investigational new drug

56
Q

Will produce 100% bioavailable drug:
a. IV
b. IM
c. PO
d. All of the above

A

a. IV

57
Q

Lactated Ringer’s Solution contains the following, EXCEPT:
a. NaCl
b. KCl
c. CaCl2
d. MgCl2

A

d. MgCl2

58
Q

Method of sterilization that is best suited for extemporaneous preparation of sterile solutions:
a. Dry heat sterilization
b. Sterilization by filtration
c. Bacterial filtration
d. Steam sterilization

A

c. Bacterial filtration

59
Q

Long-acting basal insulin preparation intended for once daily SC administration at bedtime inn the treatment of type 1 DM in adults and children
a. Insulin zinc suspension
b. Insulin glargine
c. Insulin infusion pumps
d. Isophane insulin suspension

A

b. Insulin glargine

60
Q

Absorption bases, EXCEPT:
a. Wool fat
b. Hydrophilic petrolatum
c. Aquaphor
d. Lanolin

A

d. Lanolin

61
Q

Solid or semisolid adhesive masses spread on a backing of paper, fabric, moleskin or plastics:
a. Plasters
b. Pastes
c. Cataplasm
d. Dressing

A

a. Plasters

62
Q

Part of a transdermal drug delivery system that stores and releases the drug at the absorption site:
a. Backing layer
b. Adhesive layer
c. Drug reservoir
d. Release liners

A

c. Drug reservoir

63
Q

Criteria for satisfactory suppository bases, EXCEPT:
a. Low melting point
b. Inert
c. Solid at room temperature
d. Non-irritating

A

a. Low melting point

64
Q

Dosage form with fastest to slowest drug release
a. Suspension - aqueous solution - powder - capsule - tablet coated tablet
b. Suspension- aqueous solution - powder - capsule - coated tablet - tablet
c. Aqueous solution - suspension - powder - capsule - tablet - coated
tablet
d. Aqueous solution - suspension -
powder - capsule - coated tablet - tablet

A

d. Aqueous solution - suspension -
powder - capsule - coated tablet - tablet

65
Q

Effects of metabolism to drugs, EXCEPT
a. Conversion of active form to inactive
metabolite
b. Conversion of prodrug to inactive
metabolite
c. Conversion of inactive form to active
form
d. Conversion of prodrug to active drug

A

b. Conversion of prodrug to inactive
metabolite

66
Q

Which of the following will undergo
first-pass effect?
a. Ciprofloxacin (Ciprobay) 500 mg Film-Coated Tablet
b. Slow IV infusion of Potassium Chloride in 5% Dextrose
c. Isosorbide dinitrate (Isordil) 5 mg Sublingual tablet
d. Paracetamol (Opigesic) 125 mg Suppository

A

a. Ciprofloxacin (Ciprobay) 500 mg Film-Coated Tablet

67
Q

What is the Henderson-Hasselbalch Equation for weak acids?
a. pH = pKa + log [𝑖𝑜𝑛𝑖𝑧𝑒𝑑] [𝑛𝑜𝑛−𝑖𝑜𝑛𝑖𝑧𝑒𝑑]
b. pH = pKb + log [𝑖𝑜𝑛𝑖𝑧𝑒𝑑] [𝑛𝑜𝑛−𝑖𝑜𝑛𝑖𝑧𝑒𝑑]
c. pH = pKw - pKb + log [𝑖𝑜𝑛𝑖𝑧𝑒𝑑] [𝑛𝑜𝑛−𝑖𝑜𝑛𝑖𝑧𝑒𝑑]
d. pH = pKw - pKb + log [𝑛𝑜𝑛−𝑖𝑜𝑛𝑖𝑧𝑒𝑑] [𝑖𝑜𝑛𝑖𝑧𝑒𝑑]

A

a. pH = pKa + log [𝑖𝑜𝑛𝑖𝑧𝑒𝑑] [𝑛𝑜𝑛−𝑖𝑜𝑛𝑖𝑧𝑒𝑑]

68
Q

Anionic surfactants, EXCEPT:
a. SLS
b. Amine Soaps
c. Alkali metals
d. Lecithin

A

d. Lecithin

69
Q

Primarily used to produce
multi-particulates for controlled release applications:
a. Coating
b. Aggregation
c. Spherization
d. Suspension

A

c. Spherization

70
Q

May cause sticking of tablets to the die and build-up of materials on the punch faces, EXCEPT:
a. Addition of a lubricant
b. Excessive moisture
c. Unpolished surfaces of punch and
dies
d. Soft tablets

A

a. Addition of a lubricant

71
Q

Moisture content of hard gelatin capsules?
a. 6-10% SOFT
b. 12-16%
c. 50-60%
d. 1-2%

A

b. 12-16%

72
Q

What is the smallest size of hard gelatin capsules?
a. 000
b. 1
c. 5
d. 5000

A

c. 5

73
Q

Ideally, the specific gravity of alcohol must be determined at what temperature?
a. 25 C
b. 15.56 C
c. 100 C
d. Any temperature

A

b. 15.56 C

74
Q

Ideal filtration method for viscous liquids:
a. Gravity filtration
b. Vacuum filtration
c. Pressure filtration
d. None of the above

A

a. Gravity filtration

75
Q

Parent compound of dyes:
a. Phenol
b. Alcohol
c. Aniline
d. Benzene

A

c. Aniline

76
Q

Type of drying method that employs a wet solid in thermal contact with hot surface:
a. Convective drying
b. Conductive drying
c. Radiation drying
d. None of the above

A

b. Conductive drying

77
Q

The process that involves the removal of a solid from a fluid, or a fluid from another fluid.
a. Separation
b. Distillation
c. Comminution
d. Clarification

A

d. Clarification

78
Q

The complete set of activities to product a drug that comprise production and quality control from dispensing of materials to the release for distribution of the finished products.
a. Retailing
b. Wholesaling
c. Distribution
d. Manufacturing

A

d. Manufacturing

79
Q

Closure commonly used for sterile products:
a. Paper
b. Metal
c. Rubber
d. Glass

A

c. Rubber

80
Q

The mechanical process of reducing particle size of solids:
a. Milling
b. Mixing
c. Attrition
d. Fusion

A

b. Mixing

81
Q

This contains the revised rules and regulations governing the generic labelling requirements of drug products for human use.
a. AO 2008-0016
b. AO 2016-0008
c. AO 55 s. 1988
d. AO 2014-0034

A

b. AO 2016-0008

82
Q

Brand name means:
a. Description of the chemical structure
of the drug or medicine
b. Proprietary name given by the
manufacturer
c. Description of internationally
recognized active ingredient
d. Name of the manufacturer

A

b. Proprietary name given by the
manufacturer

83
Q

This is an organization-wide effort to infuse quality into every activity in a company through continuous improvement.
a. Quality Circles
b. Managerial Ethics
c. Work Specialization
d. Total Quality Management

A

d. Total Quality Management

84
Q

According to RA 10918, pharmaceutical establishments/outlets where the direct and immediate control and supervision of a duly registered and licensed pharmacist is required, under pertinent law provisions are categorized as _______.
a. Category A
b. Category B
c. Category C
d. Category D

A

a. Category A

85
Q

The following vaccines may be
administered by a licensed and trained pharmacist, EXCEPT:
a. Cervical cancer
b. Flu
c. Pneumococcal
d. None of the choices

A

d. None of the choices

86
Q

This refers to a method of secret writing or use of characteristic style or symbol by substituting other letter/s or character/s for the letter/s intended, for the purpose of misleading consumer.
a. Cipher
b. Signa
c. Set
d. Anecdote

A

a. Cipher

87
Q

Counterfeit pharmaceutical products, EXCEPT:
A. Withwrongingredients
B. Withoutactiveingredients
C. Withtornpackaging
D. Insufficient quantity of active
ingredients

A

C. Withtornpackaging

88
Q

Who shall take charge and have custody of all dangerous drugs, plant sources, controlled precursors, and essential chemicals that are confiscated, seized, or surrendered?
a. DDB
b. FDA
c. PDEA
d. DOJ

A

c. PDEA

89
Q

PIC/S refers to
a. Pharmacist Institution Compounding Strategy
b. Pharmaceutical Inspection Cooperation Scheme
c. Philippines Industrial Cooperation Scheme
d. Pharmaceutical International Congress Summit

A

b. Pharmaceutical Inspection Cooperation Scheme

90
Q

Labelling requirements apply to:
a. Investigational drugs
b. Foreign donations of drug products
c. Extemporaneous preparation
d. Biological Products

A

d. Biological Products

91
Q

The Comprehensive Dangerous Drugs Act of 2002 is:
a. RA 6425
b. RA 9165
c. RA 6675
d. RA 9465

A

b. RA 9165

92
Q

Applicable S-tax for prescribers of dangerous drugs:
a. S-1 License
b. S-2 License
c. S-3 License
d. S-4 License

A

b. S-2 License

93
Q

The following are barriers to communication, EXCEPT:
a. Emotions
b. Language
c. National Culture
d. Protectiveness

A

d. Protectiveness

94
Q

The registration of a pharmacist shall be renewed every:
a. 1 year
b. 2 years
c. 3 years
d. 5 years

A

c. 3 years

95
Q

The PDCA cycle was proposed by:
a. Walter A. Shewhart
b. Shewhart A. Walter
c. Gallup Organization
d. None of the choices

A

a. Walter A. Shewhart

96
Q

This is the calculation of how may sales or revenue an organization need to cover cost of operation
a. Forecasting
b. Break-even analysis
c. Scheduling
d. Management by objectives

A

b. Break-even analysis

97
Q

Earliest senior citizen age in the Philippines
a. 60
b. 65
c. 61
d. 55

A

a. 60

98
Q

Device means the following, EXCEPT:
a. Instrument
b. Apparatus
c. Container
d. Contrivances

A

c. Container

99
Q

Brand name is:
a. Description of the chemical structure of the drug or medicine
b. Proprietary name given by the manufacturer
c. Description of internationally recognized active ingredient
d. Name of the manufacturer

A

b. Proprietary name given by the manufacturer

100
Q

Prescription record books must be preserved for not less than:
a. 1 year
b. 2 years
c. 3 years
d. 4 years

A

b. 2 years

101
Q

This refers to any person who acts as a jobber, merchant, broker or agent, who sells or distributes for resale pharmaceuticals, proprietary medicines or pharmaceutical specialties.
a. Retailer
b. Wholesaler
c. Liaison officer
d. Prescriber

A

b. Wholesaler

Samplex Module 5 (1 decks)

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