Module 5 Flashcards
Plasma proteolytic systems
- complement
- kinin
- coagulation
- fibrinolytic
Protease inhibitors
-a1 antitrypsin
-a2 macroglobulin
- antithrombin 3
Eryhropoeisis steps
Hematopoetic stem cell > proerythroblast > basophilic erythroblast > polychromatophilic erythroblast > orhtochromatic erythroblast > reticulocyte > erythrocyte
Name of anemia where cell becomes bigger, loses elasticity, and lifespan is brought down to 30 days
And not enough RBC can be produced
Megaloblastic anemia
What causes the release of the EPO hormone
A decrease in tissue oxygenation
What facilitates the growth and reproduction of stem cells
Interleukin 3
What are the factors that can cause anemia
B12 and folic acid deficiency
Types of anemia
-megaloblastic
-aplastic
-iron deficiency (microcytic)
- polycythemia
- thalassemia
- pernicious anemia
- sickle cell anemia
- Hemolytic
- hereditary spherocytosis
Whats the name of the disease where the mothers antibodies fight off the babys blood Rh?
Erythroblastosis fetalis
What kind of blood type do you have if you dont carry a D antigen?
Rh (+)
Platelets production steps
Hemocytoblast > megakaryoblast > promegakaryocyte > megakaryocyte > platelet
What do platelets secrete after they bind to the damaged vessel?
Thrombin, ADO, thromboxin A2, serotonin
What activates fibrinogen?
Thrombin
What can cause a decrease in coagulation (increase in bleeding) in patients?
Vitamin k deficiency
Which cell type is associated with infections and can fight them off?
Eosinophils