Module 5 Flashcards

1
Q

Plasma proteolytic systems

A
  • complement
  • kinin
  • coagulation
  • fibrinolytic
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2
Q

Protease inhibitors

A

-a1 antitrypsin
-a2 macroglobulin
- antithrombin 3

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3
Q

Eryhropoeisis steps

A

Hematopoetic stem cell > proerythroblast > basophilic erythroblast > polychromatophilic erythroblast > orhtochromatic erythroblast > reticulocyte > erythrocyte

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4
Q

Name of anemia where cell becomes bigger, loses elasticity, and lifespan is brought down to 30 days
And not enough RBC can be produced

A

Megaloblastic anemia

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5
Q

What causes the release of the EPO hormone

A

A decrease in tissue oxygenation

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6
Q

What facilitates the growth and reproduction of stem cells

A

Interleukin 3

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7
Q

What are the factors that can cause anemia

A

B12 and folic acid deficiency

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8
Q

Types of anemia

A

-megaloblastic
-aplastic
-iron deficiency (microcytic)
- polycythemia
- thalassemia
- pernicious anemia
- sickle cell anemia
- Hemolytic
- hereditary spherocytosis

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9
Q

Whats the name of the disease where the mothers antibodies fight off the babys blood Rh?

A

Erythroblastosis fetalis

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10
Q

What kind of blood type do you have if you dont carry a D antigen?

A

Rh (+)

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11
Q

Platelets production steps

A

Hemocytoblast > megakaryoblast > promegakaryocyte > megakaryocyte > platelet

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12
Q

What do platelets secrete after they bind to the damaged vessel?

A

Thrombin, ADO, thromboxin A2, serotonin

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13
Q

What activates fibrinogen?

A

Thrombin

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14
Q

What can cause a decrease in coagulation (increase in bleeding) in patients?

A

Vitamin k deficiency

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15
Q

Which cell type is associated with infections and can fight them off?

A

Eosinophils

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16
Q

Innate vs adaptive immunity

A

Innate:
- not specific, no memory, occurs before or after contact with pathogen, first line of defense
Adaptive:
- specific, develops memory, has B and T cells, occurs after contact, longer defense period

17
Q

Antibodies and where they belong

A

“GAMED”
IgG: Gestation (placenta)
IgA: Airway (nodes, saliva, breathing tract)
IgM: lyMph fluid (infections)
IgE: allErgies (least abundant)
IgD (Dumb, can bind to basophils and mast cells)