Module 4 -Support and Movement Flashcards
Name the three types of muscles. Where are they found and which ones are striated?
- Smooth muscle
- found in the gastrointestinal tract, blood vessels, eyes, etc
- non-striated - Skeletal muscle
- everywhere
- striated, parallel - Cardiac muscle
- only found in the heart
- striated, non-parallel
What are the 4 features that all muscles have?
Contractility - ability to shorten and thicken, producing force
Excitability - responds to stimuli
Extensibility - ability to be stretched without damaged
Elasticity - ability to store energy and recoil to resting length
CEEE?
Xcxl
What are the three proteins in a sarcomere? Do they anchor to the M or Z line?
Myosin - anchors to M
Action - anchors to Z line
Titin - anchors to myosin and the z line
Name the thick and thin filaments in a sarcomere.
Thick = myosin Thin = actin
Explain actin and myosin crossbridging.
Myosin heads attach to the actin binding sites. The myosin then pulls the muscle across, shortening the muscle and producing force.
How does actin / myosin crossbridging begin. Discuss: tropomyosin, troponin and calcium
Tropomyosin wraps around actin and blocks the myosin binding sites. Another protein, troponin, is attached to tropomyosin.
When the AP reaches the neuromuscular junction, calcium ions are released from the sacroplasmic reticulum. These ions bind to troponin , changing the shape of tropomyosin and revealing the myosin binding sites.
What role does ATP play in actin/ myosin crossbridging?
ATP binds(?) to myosin and extends its head so that it can reach the actin
How does crossbridging end and the muscle relax?
It ends when calcium and ATP are no longer available
What factors influence force production of a muscle?
- muscle architecture
- sarcomere length
- single motor unit
- contraction type
What value is the greatest predictor of force? And how is it calculated?
Physiological cross sectional area (PCSA)
= muscle volume / fibre length
Muscle volume is determined using an ultra sound.
An uneven amount of force / imbalance of forces acting on a joint could cause pain. (E.g. knee pain)
Describe the 3 components of the parallel elastic component (connective tissue).
Endomysium (within) - surrounds each muscle fibre
Perimysium (surrounding) - groups muscle fibres into fascicles
Epimysium (above) - tissue that surrounds skeletal muscle
Endo - peri - epi
What is the series elastic component of a muscle?
Titin and tendon
How do single motor units affect the amount of force that can be produced?
The more units engaged in an action potential,
more muscle fibres are activated. Therefore, more motor units engaged = more force
Describe the difference between slow twitch and fast twitch fibres.
Slow Oxidative (uses oxygen for energy) Low forces Fatigue resistant Contains many mitochondria and myoglobin.
Fast
Powered by glycolysis
Can generate more force
Fatigue quickly
What are the 3 different types of fibres? Describe, and give an example of Hennemans size principle.
Type 1 = slow, oxidative, low force, fatigue resistant
Type 2A = fast, oxidative, medium force, will fatigue
Type 2B = fast, glycolic, high force, quickly fatigue
Henneman’s size principle = smaller units are recruited first. From type 1 -2A-2B
For example, normal breathing, faster breathing, cough