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PHRM30003: Drug Treatment of Disease > Module 4: Managing respiratory diseases > Flashcards

Module 4: Managing respiratory diseases Flashcards

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16
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What diseases are COPD an umbrella term of?

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  1. Emphysema = complete destruction of lung tissue
  2. Bronchioolitis = inflammation of small airway
  3. Chronic Bronchitis = overproduction of mucus
17
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what is the whole-of-life disease trajectories?

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injury to lungs early in life = increase COPD risk
* air pollution, social disadvantages, environmental factors

18
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how irreversible changes in lung structure cause airflow limitation, how this is worsened by inflammation

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  • destruction of lung tissue in ddep lung = elastic fibres broken down = during expiration small airways collapse = inspiration they open due to physical forces = easily collapse in expiration = easy to get air in but not out
  • starts at the smallest airway - destruction
  • flow of air through small tubes
  • loss of surface area for gas exchange
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how this pathobiology relates to bronchodilator therapy and its limitations

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20
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the important role of infection and recurrent exacerbations and effects of treatments

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PHRM30003: Drug Treatment of Disease (3 decks)

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