Module 4 - Complex Resp. Flashcards

(75 cards)

1
Q

stimulated neural receptor along the respiratory tree → cough center in the medulla → complex reflex arc efferent pathway to the expiratory musculature

Acute (lasting <3 weeks), subacute (lasting 3 to 8 weeks), and chronic (persisting beyond 8 weeks).

A

Chronic Cough

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2
Q

Three most common causes of chronic cough with NORMAL chest radiography, no smoking, or an ACE include

A

corticosteroid-responsive eosinophilic airway diseases (asthma, cough variant asthma, and eosinophilic bronchitis)
upper airway cough syndrome (postnasal drip syndrome)
GERD

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3
Q

A cough associated with constant throat clearing and thick mucus production, especially on rising from bed

A

Upper airway cough and sinusitis

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4
Q

A cough that lasts for 3 consecutive months for more than 2 consecutive years

A

chronic bronchitis

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5
Q

A sudden onset of cough in the supine position with an associated sour taste in the mouth

A

GERD

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6
Q

A cough associated with rhinorrhea or sneezing

A

Viral or common cold-

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7
Q

Intermittent productive cough associated with wheezing

A

Asthma

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8
Q

loud hacking cough during the daytime that is nonproductive, leads to exhaustion, and is associated with emotional stress

A

Psychogenic cough-

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9
Q

Sputum Yellow-green, purulent:

A

bronchitis

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10
Q

Sputum Pink frothy

A

pulmonary edema

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11
Q

Sputum Fetid purulent

A

anaerobic infections

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12
Q

Sputum Rust colored

A

pneumococcal pneumonia

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13
Q

Chronic inflammation causes structural changes and a narrowing of the small airways and destruction of the lung parenchyma that leads to the loss of alveolar attachments to the small airways and decreases lung elastic recoil.
Cigarette smoke and an occupation that involves regular exposure to a dusty environment are the two major external factors.

A

COPD

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14
Q

The physical examination findings in early disease are often normal. (SOB, chronic cough, sputum)
Late- clubbing of fingernails, increase AP diameter (barrel chest), increase intercostal space, pursed lip breathing, tripod position, decrease expiratory, increased resonance on chest percussion
Diminished transmission of breath sounds on auscultation is the most reliable finding

A

COPD

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15
Q

Gold standard dx tool for COPD

A

Spirometry

A forced expiratory time of 6 seconds or more suggests obstructive pulmonary disease

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16
Q

Treatment for COPD

A

Smoking cessation***

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17
Q

_____ assessment: grades each question 0-5; all added up at the end for score
Cough; phlegm/mucus; chest tightness; out of breath when walking up a hill/stairs; limited in activities at home; confidence in leaving house despite lung condition; sleep; energy

A

CAT Assessment for COPD

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18
Q

None (0): No dyspnea except with strenuous activity
Slight (1): SOB when hurrying on the level or walking up a slight hill
Moderate (2): Breathlessness causes slower on-the-level walking than ppl of same age
Severe (3): stops fro breath after walking about 100m or after a few min on same level
Very Severe (4): too breathless to leave house; breathless when dressing/undressing

A

MRC dyspnea scale: grade 0-4

COPD

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19
Q

First line for intermittent symptoms of COPD

A

short acting B2 adrenergic agonist (bronchodilator)

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20
Q

first line of maintenance therapy for patients with daily COPD symptoms.

A

anticholinergics

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21
Q

Treating COPD pts with inhaled corticosteroids

A

FEV1 rechecked after 3 to 4 months of therapy

Use with LABA - reduces exacerbations for s/s COPD patients, FEV < 60, and repeated exacerbations

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22
Q

COmbination therapy for COPD

A
#1 anticholinergic and a short-acting β 2 agonist
long-acting β 2 agonist and long-acting anticholinergic, and long-acting β 2 agonist and inhaled glucosteroid
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23
Q

When should COPD pt get oxygen therapy

A

SPO2 < 88%

Prescribe O2 to keep SaO2 at or above 90% → recheck in 60-90 days to see if pt still requiring supplemental O2

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24
Q

What could it be ? …

Chest tightness and constriction

A

asthma or COPD , foreign body, bronchitis

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25
What could it be ? ... | Excessive work or effort
pleural effusion, severe kyphoscoliosis, myasthenia gravis, guillain barre syndrome cystic fibrosis
26
What could it be ? ... | Air hunger
PE, pneumonia, CHF, altitude, cystic fibrosis, metabolic acidosis, hypoxia or hypercapnea, severe anemia or carbon monoxide poisoning.
27
SUDDEN onset of dyspnea...
heralds serious cardiopulmonary disease (PE, pneumothorax, MI)
28
Dx cause of dyspnea
PA/ Lateral chest (CHF, COPD, pneumonia) Pulm/ thromboembolic related= D dimer, V/Q scan, or pulmonary angiography (definitive) Lower extremities- doppler of lower extremities Cardiac related = HF exacerbation- BNP or NTproBNP EKG
29
Expectoration of blood from the lunch parenchyma or tracheobronchial tree ( small amounts to blood streaked sputum) Most common causes: acute and chronic bronchitis, lung cancer, pneumonia, tuberculosis (highest in developing countries)
Hemoptysis
30
What would be an urgent eval with Hemoptysis?
Indications for referral or hospitalization Abnormal gas exchange, hemodynamic instability, massive hemoptysis ( > 200 mL/ 48 hr or > 50 ml per episode) Resp comorbidities. Heart disease, a fib, heart valves etc.
31
Dx Hemoptysis with chest x ray... what to look for?
( to help localize bleeding and identify the cause) Crescent sign = air-fluid level of lung abscess (mycetoma) Nodule that suggests neoplasm Evidence of volume loss consolidation/ obstruction
32
Dx Hemoptysis with chest CT... when/ what/ to look for?
Initial eval For pts at high risk of malignancy who have suspicious findings on X Ray. Consider for pts ( > 40, smoking hx of at least 30 packs-year) who demonstrate negative or non localized findings
33
single most important and modifiable risk factor for lung cancer
tobacco use
34
USPSTF 2021 Recommends Lung Cancer Screening for
Adults aged 50-80 years old, with a 20 pack-year smoking history and currently smoke or have quit within the past 15 years. Discontinue: Once a person has not smoked for 15 years or develops a health problem that substantially limits life expectancy or the ability or willingness to have curative lung surgery. Screen with low DOSE CT SCAN annually
35
s/ s of pneumothorax
S/S: steady ache/tightness in chest, SOB, dyspnea, tachycardia
36
Sx and tx of pneumothorax
Chest X-ray Tx: quick evaluation! from PCP → ER Watch/wait not acceptable in primary care
37
Patient presentation: SOB, dyspnea on exertion, chest pain, cough, fatigue of unknown origin
P.E.
38
Validated in primary care and results in lowest risk of missed PE if imaging was withheld
Wells Criteria
39
If you think your pt has a PE →
ED for eval and management D dimer + CTA (no CTA for renal failure pt; ventilation perfusion (VQ) scan is best)
40
Complex multisystem dx that causes high BP in the arteries of the lungs PH defined as an increase in mean pulmonary arterial pressure (mPAP) >25mm Hg at rest as assessed by right heart catheterization
Pulm HTN
41
WHO classification groupings for Pulm HTN
``` Group I (pulmonary arterial hypertension) Causes: idiopathic, familial, HIV, drugs/toxins ``` ``` Group II (left heart dx) Causes: CAD, HBP, heart valve dx, age ``` ``` Group III (Lung diseases and/or hypoxemia) Causes: COPD, ILD, low O2 levels ``` ``` Group IV (Chronic thrombotic and/or embolic dx) Causes: organizing blood clots ``` ``` Group V (misc) Causes: sarcoidosis, sickle cell anemia, metabolic disorders ```
42
early s/s of pulm HTN
Early s/s: Exertion induced sx; SOB, weakness, angina, syncope Less common: dry cough, exercise induced n/v Sx at rest not typical in early PH
43
mod- severe s/s of pulm HTN
Holosystolic murmur that increases with inspiration, diastolic murmur Pulsatile liver Distention of jugular veins Hepatomegaly peripheral edema* Ascites* Low BP, diminished pulse pressure, cool extremities, reduced cardiac output, peripheral vasoconstriction* If present with any of these symptoms: PROMPT referral to specialty care
44
PCP Management of pulm HTN?
After specialist consult and recommendations, PCP should Offer routine f/u care: 3-6 mos depending on severity and compliance Address adherence to diet, exercise, appropriate vaccinations, avoidance of pregnancy Regular testing done by specialty team Med rec
45
Systemic dx of unknown cause characterized by presence of noncaseating (no necrotic changes, non-infectious origin) granulomas Lungs and intrathoracic LN → most common sites Other sites: skin, eyes, liver, spleen, ENT, neuro, bone marrow, kidney, bone/joint, heart, parotid-salivary gland
Sarcoidosis
46
Women, 20-50, black, scandinavian, japanese, 1st degree relative with disease CM Nonspecific sx: SOB, unexplained cough, fever Specific sx: bilateral hilar lymphadenopathy, erythema nodosum, polyarthritis, uveitis, Lofgren syndrome, Heerfordt syndrome, Lupus pernio Referral to pulmonary specialist
Sarcoidosis
47
How to dx Sarcoidosis
3 criteria needed: 1: compatible clinical and radiological presentation PCP: CXR for identification, CT scan for staging, diff dx, interstitial changes; specialist: will run further and dx-specific testing 2: pathologic evidence of noncaseating granulomas 3: exclusion of other diseases with similar findings (ex: infections, malignancy)
48
How to tx Sarcoidosis
Tx not indicated for pt with asymptomatic stage ½ dx; spontaneous resolution common First line therapy: corticosteroids (10-15 mg/day) 2nd line: methotrexate, azathioprine (Imuran), Leflunomide (Arava), Biologic agents, corticotropin For refractory or complex cases (managed by pulm)
49
sudden onset of REM related muscle atonia precipitated by emotion during wakefulness
Cataplexy
50
How to Dx Narcolepsy?
Overnight PSG - to exclude underlying causes… if nothing shows up then Perform MSLT- multiple sleep latency test -
51
how to tx narcolepsy?
Stimulat meds- dextroamphetamine and methylphenidate Modafinil = wakefulness promoting agents (not amphetamine based = less risk of habit forming, longer acting = increased insomnia risk) Cataplexy tx with REM suppressing meds = SSRIs, SNRIs, y-hydroxybutyrate
52
10% of cases, brain doesn't signal body to breathe); obstructive (airway collapses) → can co-occur
Central sleep Apnea
53
STOPBANG acronym for sleep apnea
Snore loudly, tired during day, observed apnea, pressure (treated for HTN), BMI >35, Age >50, Neck >16” female; 17” male, gender (male)
54
Used for anesthesia for grading difficult airway for intubation; can be used for SA as well Normal → grade 4 (when sticking out tongue, can’t see soft palate or uvula)
Mallampati score
55
Sleep Apnea Clinical Score (SACS)
``` Snoring (3 pts) Apnea (3 pts) Circumference (neck in cm) Systemic HTN (4 pts) Low risk <43; mod 43-48; high >48 ```
56
no interference between x-ray particles and the casetter; black (air and fat); hypodensity
Radiolucent
57
interference- blocks radiation; white (bone, metal, calcium in tumors/deposits)
Radiopaque
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shades of gray (organs, soft tissues, muscles)
Density of tissues
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pt chest up against cassette; pt is backward
PA view
60
pt facing forward, cassette in back
AP view
61
Method for reading CXR
AABCDF Method - Adequacy - Airways - Bones - Circulation - Diaphragm - Final Look
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step 1: Adequacy
Pt identifiers, who read it, marker from tech (L, R), costophrenic angles visible, apices (top) of lungs visible, dark area above clavicle, full inspiration (defined as 9 or more ribs above diaphragm)
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Step 2 airways
Is the trachea midline (sometimes slightly shifted with enlarged thyroid), bronchi, look side to side and top to bottom and compare Left lung: 2 lobes; upper, lower (middle area called the lingula, butts up against border of the heart)
64
Step 3 Bones
Sternum, ribs, scapula; as well as spinal process and clavicles
65
Step 4: Circulation (heart and vessels)
Measure cardiac ratio (can ONLY do in PA film) Take widest heart dimension compared to widest lung dimension; should be half the size or less of lung Mediastinal borders Aortic knob LV (make sure you can see it + size) RA
66
Step 5 Diaphragm
Shape (domed, shaped like 2 hills), height (R 1-3cm higher → normal because liver is below), costophrenic angles
67
Step 6 Final Look
Corners of the film, tracheal deviation, retrocardiac lung (lateral view), “below” the diaphragm if visible, peri-hilar regions
68
more comprehensive than spirometry! (done in pulmonary office) Looks at lung vol, gas exchange, diffusion capacities and more
PFT
69
Simplest PFT test, looks at vol of inspiration and expiration at 1 and 6 seconds; done in the office Must withhold inhalers night before for test to be effective
Spirometry
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obstructive lung diseases
reduction in airflow- some air remains in lung after full expiration COPD ASTHMA CHF
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restrictive lung diseases
reduction in lung volume - difficulty taking air inside the lung - interstitial lung disease, scoliosis, neuromuscular cause
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If FVC/FEV1 both low, but ratio normal
restrictive lung diseases
73
low FEV1: FVC ratio
obstructive lung diseases
74
air exhaled in 1 second; norm 80-100
FEV1: VC ratio
75
method If testing for obstructive lung pattern with spirometry
Albuterol 2-4 puffs, wait 15 min → repeat test If measures >12% or 200mL → reversible obstructive pattern (asthma) If no reversal If don't fit pattern for COPD; refer to pulmonology for PFTs, bronchoprovocation testing