Module 3: Proteins bound to membrane

Question 1

2 types of proteins bound to membranes

Answer 1

Integral membrane proteins
Peripheral membrane proteins

Question 2

3 types of membrane bound proteins

Answer 2

-Transmembrane proteins
- Lipid-anchored proteins
-peripheral membrane protiens

Question 3

Physically embedded in the hyrdorphobic portion

Answer 3

Transmembrane protein

Question 4

amino acid of the protein covalently attached to a lipid

Answer 4

lipid-anchored protein

Question 5

Deescribe transmembrane proteins

Answer 5

-traverse one leaflet to another
-non polar AA attached to the hydrophobic interior

Question 6

transmembrane protein segment

Answer 6

-folds into alpha helix
-stabe due to interaction of NP amino acid and NP tails

Question 7

Describe lipid-anchored proteins

Answer 7

-can easily associate to membrane due to lipid molecule
-covalently attached to AA chain

Question 8

Describe peripheral membrane proteins

Answer 8

-non-covalently bound to transmembrane proteins
-project on the polar head groups
-bound by hydrogen bonds, ionic bond or both
-some contain lipoproteins

Question 9

Importance of interaction between integral and peripheral membrane proteins

Answer 9

-important for energy metabolism and transport