Module 3 MCQ

Question 1

Which one of the following was NOT a finding from the Human Genome project?

(A) Humans have fewer genes than expected.
(B) Approximately 1.5% of human DNA sequence codes for functional proteins.
(C) The genomes of all humans are 99.9% similar to each other.
(D) Approximately 75% of the human genome is non-functional ‘junk’ DNA.

Answer 1

(D) Approximately 75% of the human genome is non-functional ‘junk’ DNA.

Question 2

Single nucleotide polymorphisms (SNPs) are:

Answer 2

Mostly inherited from your parents.

Question 3

The presence of Neanderthal DNA within some modern human genomes:

Answer 3

Is not seen in the genomes of modern African humans.

Question 4

Comparing Human Genome sequences has led to the following suggestion:

Answer 4

Early modern humans interbred with other ancient human species.

Question 5

Heritable mutations are always:

Answer 5

germline.

Question 6

Huntingtonʹs disease is an autosomal dominant disorder. This indicates that one mutant allele of the gene is enough to give you the disease. A dominant disorder of this kind is most likely to be caused by a:

Answer 6

gain of function mutation.

Question 7

If a rare disease is autosomal dominant, what is the probability of a grandchild inheriting disease from an affected grandparent?

Answer 7

0.25

Question 8

A corrected copy of a person’s defective CFTR gene is introduced into their lung epithelial cells by means of a plasmid vector. The plasmid enters the nuclei of these cells, and a corrected protein can be expressed. Which process is being described here?

Answer 8

gene therapy

Question 9

Which one of the following statements is NOT correct?
Embryonic stem cells:

(A) can contribute to both the placenta and the embryo.
(B) are pluripotent.
(C) can make all the structures of the embryo.
(D) are derived from the inner cell mass of mammalian embryos.

Answer 9

(A) can contribute to both the placenta and the embryo.