Module 3-4 Flashcards
What are the two ways to get mutations
Germline and somatic
Which mutation can be passed on:
Germline
How can you get mutations
inherited or acquired
what are the 3 types of inheritance
Y and X linked dominant, X and Y linked recessive, autosomal dominant/recessive inheritance
out of the two functions which on is the dominate gene that wont be replaced in sequencing
“Gain of function”
What are some examples of Monogenic disease
Cystic fibrosis, Sickle cell anemia, Huntington’s disease
What are examples of Polygenic Diseases
Diabetes type 2, Hypertension, Coronary artery disease
how dose understanding our genome help us
known where we come from, genetic variation, evolution relationships, research into diseases
what dose comparing our genomes to other homo species help understand
How we should think about them, what genes are considered a “gift” from other homo species, that these variations are important
how similar are all humans geneticaly
99.9%
what dose sequencing tell us about the genome
it is dynamic
why is variation important
key driver of evolution, avoid population crash (inbreeding)
