Module 3 Flashcards

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1
Q

What is Mendel’s First Law?

A

The two alleles of a gene segregates from one another during gamete formation.

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2
Q

Where does Mendel’s first law occur?

A

In anaphase 1

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3
Q

What is the product rule?

A

The probability of 2 independent events both occurring = the product of their probabilities.
Used for the genotype ratio.

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4
Q

What is the sum rule?

A

The probability of the occurrence of mutually exclusive events is the sum of the probabilities of the individual events.

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5
Q

What is complete dominance?

A

when one allele is fully dominant over the other.

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6
Q

What is incomplete dominance?

A

Gene interaction in which both alleles of a gene at a locus are partially expressed, often resulting in an intermediate or different phenotype.

Example:
White, pink, and red flowers. Where the pink flowers show incomplete dominance.

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7
Q

What is co-dominance?

A

A type of inheritance in which two versions (alleles) of the same gene are expressed separately to yield different traits in an individual.

Example: White, white/red, and red flowers. The red/white flowers show co-dominance.

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8
Q

What is epistasis?

A

Where the expression of one gene is affected by the expression of one or more independently inherited genes.

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9
Q

What are sex-linked genes?

A

Characteristics that are influenced by genes carried on the sex chromosomes.

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10
Q

What is constitutive gene expression?

A

When the gene is expressed at all times (transcribed and translated)

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11
Q

What are promoters and operators made out of?

A

DNA

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12
Q

What is Mendel’s second law?

A

The segregation of alleles of one gene is independent of the segregation of the alleles of another gene.

This is linked to dihybrid crosses.

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13
Q

How do the 3:1 ratios compare to the 9:3:3:1 ratios?

A

The 9: 3: 3:1 ratio is a PRODUCT of the 3:1 ratio.

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14
Q

What phenotypic ratio do you get when you cross a heterozygous and a homozygous recessive

A

1:1:1:1

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15
Q

What is constitutive gene expression?

A

When the gene is expressed (transcribed and translated) at all times.

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16
Q

What is regulated gene expression?

A

When a gene is expressed only when required - usually due to regulation of transcription.

17
Q

What is an operon?

A

A unit of gene expression in bacteria.

An operon is a cluster of genes that are transcribed together to give a single messenger RNA (mRNA) molecule, which therefore encodes multiple proteins

18
Q

What is a promoter?

A

a region of DNA upstream of a gene where relevant proteins (such as RNA polymerase and transcription factors) bind to initiate transcription of that gene.

19
Q

What is an operator?

A

the regulatory protein binding site - controls the ON/OFF switch. Stretches of DNA sequences.

20
Q

What is a repressor?

A

A protein that can switch the gene expression OFF - stops transcription

21
Q

What is a co-repressor?

A
22
Q

What is a repressible trp operon?

A

When its default state is ON. It is switched OFF (repressed) by tryptophan (trp).

ON = transcribed

23
Q

What does polycistronic mRNA mean?

A

Many genes.
It is a mRNA that encodes several proteins and is characteristic of many bacterial and chloroplast mRNAs.

24
Q

What are histone proteins?

A

Positively charged proteins that are attracted to the negatively charged DNA (due to phosphate group). Their tails stick out, allowing chemical modification.

25
Q

What is an example of a chemical modification on a histone?

A

The attachment of acetyl groups to the histone tils. These help neutralise their positive charge.
When this occurs in/near a gene, the most likely effect will be that the gene will be available for transcription. This is because the histones will bind less tightly to the DNA.

26
Q

What is the role of RNA polymerase?

A

Copying a DNA sequence into an RNA sequence, during the process of transcription.

27
Q

TRUE/FALSE: introns are found in both prokaryotes and eukaryotes

A

False.
Only found in prokaryotes.

28
Q

What are exons?

A

Expressed sequences of the DNA

29
Q

What are introns?

A

interrupting sequences that are spliced out by spliceosomes.

30
Q

What are control elements?

A

They are specific sequence of DNA upstream from promoter, that bind to the activator proteins. They increase the rate of transcription.