Module 22 - Neuropathology Flashcards
1
Q
A gain of function mutation in the GRIN2B gene leads to
A
Seizures
2
Q
What type of glial cells can become “reactive”?
A
Both astrocytes and microglia can participate in inflammatory processes in the brain and this can form part of the pathology in neurodegenerative disorders
3
Q
What type of channel is most commonly mutated in malignant hyperthermia?
A
Calcium
4
Q
Which of the microglial states is involved in synaptic remodelling and removes apoptotic neurons?
A
Nurturer
5
Q
What cell type is the target of the autoimmune attack in multiple sclerosis?
A
Oligodendrites
6
Q
The glial cell type that nurtures the cells of the blood brain barrier is the:
A
Astrocyte
