Module 2.1 Flashcards

1
Q

What is genetic diversity

A

Genetic variation within species (eye colours, Tre crown shape)

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2
Q

what is biodiversity

A

general term refers to the variety and variability of life on earth (genetic diversity, species diversity, ecological diversity))

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3
Q

what is population

A

a randomly breeding group of individuals that is largely isolated from others

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4
Q

what is population genetics

A

the study of genetic variation within and among populations and its response to evolutionary forces over space and time

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5
Q

why is population genetics important?

A

1) individuals exist in communities
2) genotypes of individuals are largely determines by the gene pool of the population
3) genetic diversity is defined at the population level

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6
Q

how to calculate proportion of each genotype in a population

A

number of individuals with each genotype / total individuals sampled

f(BB) = 1/4
f(Bb) = 1/2
f(bb) = 1/4

Sum must be equal to 1

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7
Q

what is allele frequencies + formula

A

proportion of an allele at a particular locus (of a gene) in a population for a diploid organism

count of specific allele / (2 * total individuals samples)

f(B) = 0.5
f(b) = 0.5

sum = 1

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8
Q

Hardy Weinberg principle

A

allele and genotype frequencies within a population will remain constant from generation to generation in the absence of other evolutionary forces

when these conditions are met, the population is said to be in hardy Weinberg equilibrium

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9
Q

what is the hardy Weinberg formula

A

p^2 + 2pq + q^2 = 1

p,q = allele frequencies

when allele frequencies are changed, the equilibrium will be reached again after one generation random mating

p+q=1

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10
Q

what is the proportion of heterozygosity in hardy Weinberg

A

2pq

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11
Q

what is the frequency of dominant in hardy Weinberg

A

p^2

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12
Q

what is the frequency of recessive in hardy Weinberg

A

q^2

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13
Q

what is heterozygosity

A

the proportion of heterozygotes for a particular locus

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14
Q

what is gene diversity

A

the proportion of polymorphic loci across genome

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15
Q

assumptions for HW principle

A

slide

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16
Q

what are the evolutionary forces

A

mutation
selection
gene flow (migration)
genetic drift (random effect)

17
Q

what is mutation

A

source of all genetic variation

18
Q

three ingredients for evolution by Darwin

A

variation, heredity, selection

19
Q

what is point mutation

A

changes in one or a few nucleotides

20
Q

how does mutation occur

A

point mutation, insertion/deletion

21
Q

mutation rate in humans

A

1.0 - 1.5 x 10^-8
30 new DNA variants with each gamete

22
Q

are most mutations good?

A

no, most are neutral or harmful
beneficial are rare

23
Q

what is selection force

A

climate, predator, selective breeding

24
Q

what is gene flow

A

movement of genes between population with gametes (pollen), individuals (seeds)

25
Q

what are effects of gene flow

A

slides

26
Q

what is genetic drift

A

change in allele frequency in a population from generation to generation due to random sampling

27
Q

bottleneck effect

A

slides

28
Q

effect of genetic drift

A

slides

29
Q
A