Module 2: Part 3 Flashcards

1
Q

Describe Crohn’s:

Be able to recognize the differences from ulcerative colitis

A
  • Granulomatous
  • Skip lesions, cobblestone
  • Mostly in the terminal end of the ilium but can be in both large and small intestine
  • Submucosa
  • Mnfts w diarrhea, wt loss, colicky abdm pain
  • Complications: Fistulas, abscesses, stricture
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2
Q

Describe ulcerative colitis:

A
  • Continuous, proximal from rectum
  • Mucosa
  • Ulcers (duh)
  • Crypt abscesses
  • Pseudopolyps
  • Mnfts w bloody diarrhea, cramping, wt loss (less than crohn’s though)
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3
Q

For someone experiencing multiple repeating episodes of IBD exacerbations, what nursing diagnosis could you make? what are some interventions to help with this?

A

Diagnosis:
Risk for ineffective therapeutic regimen management related to insufficient knowledge concerning the process and management of the disease
Interventions:
Provide pt with information regarding preventative measures eg nutritional management; a bland, low-residue, high-protein, high-calorie, and high-vitamin diet relieves symptoms and decreases diarrhea. Also providing info about the importance of the prescribed drugs.

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4
Q

Why are corticosteroids used to treat IBD?

A

These are used because they suppress the immune response, thus limiting the damage caused to the bowel by the immune system reacting to the normal flora and reducing inflm.

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5
Q

Side effects of steroids:

A
  • Decreased immune fx and wound healing
  • Increased blood glucose
  • Osteoporosis
  • Wt gain, moon face
  • Increased risk of ulcers and mood disorders
  • ‘lyte imbalances
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6
Q

How can you reduce the risks associated with steroids?

A
  • Short periods of time
  • Decrease dose over time
  • Give w food
  • Alt day doses
  • Give locally instead of systemic
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7
Q

Why is important to slowly decrease steroid doses?

A

To allow time for recovery of adrenal Fx and minimize withdrawal side effects.

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8
Q

What are symptoms of steroid withdrawal?

A
  • Hypotension
  • Hypoglycemia
  • Myalgia
  • Arthralgia
  • Fatigue
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9
Q

T or F:

Crohn’s can be transmural.

A

T, this can cause the complications: fistulas, abscesses, stricture, possible perforation = peritonitis

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10
Q

Steatorrhea may be seen in pts with Crohn’s, what is this?

A

Abnormal quantities of fat in stool, may be whitish in color.

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11
Q

Erythema nodosum may be seen in pts with Crohn’s, what is this?

A

Bruises in the adipose tissue layer, usually seen on the front of the legs below the knees

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12
Q

Ulcerative colitis causes increased risk of developing what 4 conditions?

A
  • Toxic Megacolon
  • Perforation
  • Colon Cancer
  • Nephrolithiasis
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13
Q

What is the gold standard for Dx IBD?

A

Proctosigmoidoscopy or Colonoscopy with biopsy

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14
Q

5 Dx for IBD (not including scoping):

A
  • Barium enema
  • Upper GI series (Barium study)
  • CT scan
  • CBC, Alb, K+, Na+, RFTs
  • Stool culture
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15
Q

4 surgical interventions for IBD:

A
  • Total Colectomy (ileostomy)
  • Continent ileostomy (K- pouch)
  • Temporary loop ileostomy
  • Ileoanal anastomosis with J-pouch
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16
Q

Who is at the greatest risk for developing IBD?

A

People between 15 and 30 years of age are at the greatest risk of developing IBD, followed by people between 50 and 70 years of age.

17
Q

NSAIDs have been found to _________ IBD.

A

Exacerbate

18
Q

In Crohn’s, where would you expect your pt to be experiencing the most pain?

A

In the LRQ

19
Q

T or F:

The pain experienced w Crohn’s is relieved by defecation.

A

F

20
Q

Why is pain with IBD especially prominent after meals?

A

Because food induces peristalsis

21
Q

Classification of Infliximab?

A
  • Therapeutic: antirheumatics (DMARDs), gastrointestinal anti-inflammatories
  • Pharmacologic:monoclonal antibodies
22
Q

Mechanism of action and indication of Infliximab

A
  • Action: Neutralizes and prevents the activity of tumor necrosis factor-alpha (TNF-alpha), resulting in anti-inflammatory and antiproliferative activity
  • Indication: Rheumatoid arthritis, Crohn’s
    disease, psoriatic arthritis, ankylosing spondylitis, ulcerative colitis
23
Q

Common side effects and interactions of Infliximab

A
  • Fatigue
  • Headache
  • Upper resp infct
  • Abdm pain, naus/vom
  • Dysuria
  • Many more
24
Q

Nursing considerations for Infliximab

A
  • Assess for infusion-related reactions (fever, chills, urticaria, pruritus) during and for 2 hr after infusion
  • Observe for development of new infcts
25
Q

Classification of Prednisone

A

Therapeutic: anti-inflammatories (steroidal) (intermediate acting), immune modifiers

26
Q

Mechanism of action and indication of Prednisone

A
  • Action: suppresses inflammation and the normal immune response. Has numerous intense metabolic effects
  • Indication: Used systemically and locally in a wide variety of chronic diseases including: Inflammatory, Allergic, Hematologic, Neoplastic, Autoimmune disorders
27
Q

Common side effects and interactions of Prednisone

A
  • Depression
  • Euphoria
  • HTN
  • Dec wound healing
  • Nau/vom
  • Many more
28
Q

Nursing considerations for Prednisone

A

Assess patient for signs of adrenal insufficiency (hypotension, weight loss, weakness, nausea, vomiting, anorexia, lethargy, confusion, restlessness)

29
Q

Classification of Sulfasalazine

A

Therapeutic: antirheumatics (DMARD), gastrointestinal anti-inflammatories

30
Q

Mechanism of action and indication of Sulfasalazine

A
  • Action: Locally acting anti-inflammatory action in the colon, where activity is probably a result of inhibition of prostaglandin synthesis
  • Indication: Mild-to-moderate ulcerative colitis or as adjunctive therapy in severe ulcerative colitis.
31
Q

Common side effects and interactions of Sulfasalazine

A
  • Headache
  • Diarrhea
  • Nau/vom
  • Rash
  • Fever
  • Many more
32
Q

Nursing considerations for Sulfasalazine

A
  • Monitor for allergic reaction

- Monitor in/outs