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NCM 106: PHARMACOLOGY > MODULE 2: NEUROPHARMACOLOGY - ANS DRUGS > Flashcards

MODULE 2: NEUROPHARMACOLOGY - ANS DRUGS Flashcards

1
Q

Works through neurotransmitters

A

NERVOUS SYSTEM

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2
Q

Efferent and afferent neurons will this monitory to send impulses in and out

A

External and Internal Environment

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3
Q

The environmental changes and determine the response after stimulus is sent

A

Process and Integrate

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4
Q

When was the impulses will go up to the brain and it will integrate the information

A

After the stimulus is sent

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5
Q

After determining the response, an action will be sent based on the analyzed stimulus

A

Respond by producing an action or response

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6
Q

Nervous System consist of brain and spinal cord

A

CENTRAL NS

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7
Q

Nervous System consist of afferent and Efferent neurons

A

Peripheral NS

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8
Q

Afferent is

A

Sensory and Away

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9
Q

Efferent is

A

Motor and Inwards

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10
Q

Efferent neurons consist of

A

Autonomic nervous system and Somatic Nervous system

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11
Q

Autonomic nervous system means?

A

Involuntary

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12
Q

Somatic Nervous System

A

Voluntary

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12
Q

Sympathetic means

A

Adrenergic

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13
Q

It is send impulses to the CNS

A

AFFERENT

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13
Q

Somatic Nervous System Consists of

A

Sympathetic and Parasympathetic

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14
Q

Parasympathetic means

A

cholinergic

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15
Q

Involuntary
Controls and regulates the heart, GI, respiratory system, bladder, eyes and glands

A

AUTONOMIC NERVOUS SYSTEM

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15
Q

Received impulses, transmit through the spinal cord to effector organ cells

A

EFFERENT

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16
Q

All preganglionic neurotransmitters are acetylcholine (ACH)

A

PARASYMPA NS

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16
Q

Voluntary
Innervates the skeletal muscle

A

Somatic Nervous System

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16
Q

What is the other term for AUTONOMIC NS?

A

VISCERAL SYSTEM

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17
Q

Why chemicals produced by CNS and ANS?

A

to communicate with each other in between 2 neurons

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17
Q

In Synaptic Transmission, What is the STEP of STORAGE of the neurotransmitters inside the vesicles

A

STEP 2

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17
Q

sends the message to the other neuron or synapse that bridges

A

Synaptic Gap

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17
In Synaptic Transmission, What is the STEP of SYNTHESIS of transmitters
STEP 1
17
All preganglionic neurotransmitters are norepinephrine (NE)
SYMPA NS
18
In Synaptic Transmission, What is the STEP of RELEASE of the neurotransmitter due to an action potential
STEP 3
18
In Synaptic Transmission, What is the STEP of ACTION AT THE RECEPTOR, causing RESPONSE
STEP 4
18
In Synaptic Transmission, What is the STEP of TERMINATION of transmission
STEP 5
19
What is the first termination of transmission in STEP 5?
disassociate from the receptor by reuptake in the presynaptic nerve terminal
19
What is the second termination of transmission in STEP 5?
enzymatic degradation, enzyme degrades the transmitter around the neuron
20
What is the third/last termination of transmission in STEP 5?
diffusion away from the gap
21
FIGHT OR FLIGHT RESPONSE, is it Sympathetic NS or Parasympathetic NS?
Sympathetic NS
21
What Nervous system is Adrenergic
Sympathetic NS
22
What is the receptor organ cells of adrenergic (Sympa NS)?
Alpha 1 and 2, Beta 1 and 2
22
What is the Terminal Neurotransmitter of Adrenergic (Sympa NS)?
Norepinephrine (NE)
23
REST & DIGEST RESPONSE, WHAT NERVOUS SYSTEM IS THIS?
Parasympathetic NS
24
What Nervous system is cholinergic
Parasympathetic NS
25
What is the Terminal Neurotransmitter of cholinergic (Parasympathetic NS)?
Acetylcholine (ACH)
26
What is the receptor organ cells of cholinergic (Parasympathetic)?
Nicotinic and Muscarinic
27
Inactivates acetylcholine before reaching organ cells
Acetylcholinesterase
28
SYMPA OR PARASYMPA, Constricts pupils?
Parasympa
28
SYMPA OR PARASYMPA, Dilates the pupils
SYMPA
29
SYMPA OR PARASYMPA, Constrict bronchioles, Increase secretions
Parasympa
29
SYMPA OR PARASYMPA, Dilates bronchioles?
Sympa
29
SYMPA OR PARASYMPA, Increase heart rate
Sympa
30
SYMPA OR PARASYMPA, Decrease heart rate
Parasympa
31
SYMPA OR PARASYMPA, Relaxes smooth muscles of GI
Sympa
31
SYMPA OR PARASYMPA, Constrict blood vessels
Sympa
32
SYMPA OR PARASYMPA, Relaxes uterine muscles
Sympa
33
SYMPA OR PARASYMPA, Dilates blood vessels
Parasympa
34
SYMPA OR PARASYMPA, Increase peristalsis
Parasympa
35
SYMPA OR PARASYMPA, Increase salivation
Parasympa
35
Drugs act through receptors by binding to the receptors to initiate a response or prevent a response It is similar to the fit of the right key in a lock
RECEPTOR THEORY
36
THE RECEPTOR
LOCK
36
THE DRUG
THE KEY
36
it is the drugs that BLOCKS a response
Antagonist
36
THE AFFINITY
THE KEY FITS THE LOCK
37
It enhanced cellular activity
Agonist Drug
37
it is the drug that PRODUCES a response
Agonist
38
In a normal cellular activity
Before Drug
39
It blocked cellular activity
Antagonist Drug
39
it stimulate the SNS
Adrenergic Agonist
39
it inhibits the SNS
Adrenergic Antagonist
40
It stimulate PNS
Cholinergic Agonist
41
It inhibits the PNS
Cholinergic Antagonist
42
When autonomic drugs are given, the goal is not to treat an autonomic disorder, it is to correct disorders of target organs through autonomic nerves
Pharmacologic Effect
42
ADRENERGIC AGONIST & ANTAGONIST
SYMPATHETIC NERVOUS SYSTEM
42
Blood Vessels, Vasoconstrictions, Increased blood pressure, Increased contractibility of the heart Eye, Mydriasis (pupil dilation) Bladder, Relaxation Prostate, Contraction
Alpha 1 receptor
43
Blood Vessels, Decreased blood pressure (reduced norepinephrine) Smooth muscle (gastrointestinal tract), Decreased gastrointestinal tone and motility)
Alpha 2 receptor
44
Adrenergic Agonists
Sympathomimetics
45
directly acts on the receptor sites
DIRECT ACTING SYMPATHOMIMETICS
46
increase the production of NE which will enter the receptor sites
Indirect acting Sympathomimetics
47
does both direct and indirect act
Mixed acting Sympathomimetics
47
has catechol ring and amines (proteins)
Catecholamines
47
has no catechol ring
Noncatecholamines
47
mostly used in emergency situations given thru IV
Catecholamines
48
influences one type of receptor
Selective
49
Influences ALL receptors
NON selective
49
Hypertension
Alpha 2
50
What Alpha were hypotension, nasal congestion, dilation of pupils
Alpha 1
51
heart failure, cardiac arrest, shock
Beta 1
52
asthma, premature labors of contraction
Beta 2
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NCM 106: PHARMACOLOGY (1 decks)

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