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wound care > Module 2 Key Terms > Flashcards

Module 2 Key Terms Flashcards

1
Q

cell possessing properties of fibroblasts and smooth muscle cells that cause wound contraction

A

myofibroblast

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2
Q

final phase of wound healing during which collagen matures and reorients along the liens of stress

A

maturation/remodeling

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3
Q

proteases that degrade the extracellular matrix

A

matrix metalloproteases (MMPs)

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4
Q

cell that helps initiate inflammation; secretes histamine, enzymes, and chemical mediators

A

mast cell

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5
Q

when PMNs are pushed to the sides of a vessel wall

A

margination

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6
Q

scar due to the overproduction of collagen that extends beyond the confines of the original wound

A

keloid

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7
Q

cell surface receptors that allow cells to reversibly bind to the extracellular matrix

A

integrins

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8
Q

first phase of wound healing, characterized by localized redness, heat, swelling, pain, decreased function

A

inflammation

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9
Q

a pothole-type wound that fails to build a sufficient granulation matrix

A

hypo granular

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10
Q

overproduction of collagen that stays within the confines of the original wound

A

hypertrophic scarring

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11
Q

error of the proliferative phase in which too much granulation tissue is formed and epithelialization is delayed

A

hypergranulation

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12
Q

a closed wound with tissue strength approachign normal

A

healed wound

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13
Q

temporary structure composed of vascularized connective tissue that fills the wound void

A

granulation tissue

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14
Q

dermal cells that produces collage, elastin, granulation tissue, and growth factors

A

fibroblast

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15
Q

mixture of fluid, high levels of protein, and cells

A

exudate

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16
Q

process by which keratinocytes resurface the wound defect

A

epithelialization

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17
Q

keratinocyte migration over the lip or margins of the dermis

A

epibole

18
Q

the movement of PMNs through capillary walls

A

diapedesis

19
Q

a combination of primary and secondary wound healing processes in which the wound is first observed before primary closure

A

delayed primary closure

20
Q

separation of wound margins

A

dehiscence

21
Q

substance that is poisonous to human cells

A

cytotoxic agents

22
Q

signaling protein during the inflammatory phase of wound healing

A

cytokine

23
Q

local change of polarity at the site of integumentary injury

A

current injury

24
Q

pathological shortening of scar tissue resulting in a deformity

A

contracture

25
Q

enzyme that breaks down collagen

A

collagenase

26
Q

a wound in which the epithelial integrity has been restored

A

closed wound

27
Q

movement along a chemical gradient

A

chemotaxis

28
Q

substance that attracts cells

A

chemotactic agents

29
Q

formation of new blodo vevssels

A

angiogenesis

30
Q

endothelial cell that lines vessle walls

A

angioblasts

31
Q

wound caused by scraping or friction to the skin’s surface

A

abrasion

32
Q

process by which myofibroblasts pull wound margins closer together, thereby decreasing the size of the defect

A

wound contraction

33
Q

proteases that regulate the activity of MMPs

A

tissue inhibitors of matrix metalloproteases (TIMPS)

34
Q

wound healing process in which granulation tissue is formed to fill the wound defect

A

secondary closure

35
Q

a substance released by injured cells that cause vasodilation

A

prostaglandin

36
Q

second phase of wound healing; building and regenerating phase consisting of angiogenesis, granulation tissue, formulation, wound, contraction, and epithelialization

A

proliferation

37
Q

process by which wounds heal if the wound margins can be approximated

A

primary closure

38
Q

cell that cleans the wound; secretes enzymes and inflammatory mediators

A

polymorphonuclear

39
Q

cell that helps control beeling; releases growth factors and chemotactic agents

A

platelet

40
Q

growth-promoting substance that increases or enhances cell size, proliferation, or activity

A

growth factor

41
Q

collection of necrotic cells, fibrin, collagen, and platelets that cover a superficial wound

A

scab

42
Q

cell that directs the repair process, secretes growth factors and enzymes, and destroys bacteria and debris

A

macrophage

wound care (2 decks)

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