Module 2 Cell Communication And Signalling

Question 1

Juxtacrine and gap junctions are examples of what kind of communication?

Answer 1

DIRECT

Question 2

An example of a juxtacrine cell?

Answer 2

Phagocytic cells

Question 3

Gap junctions are in animal cells only. True?

Answer 3

Yes

Question 4

What are gap junctions made of?

Answer 4

Connexons…which are made of connexins

Question 5

What is the plant equivalent of gap junctions?

Answer 5

Plasmodesmata

Question 6

Where can we find gap junctions and why?

Answer 6

Heart. Allows for synchronous connection system for heart electrical impulses.

Question 7

Example of paracrine communication?

Answer 7

Mast cells

Question 8

Example of autocrine communication?

Answer 8

Monocytes secretin interlukein 1

Question 9

Endocrine communication. 2 divs

Answer 9

Exocrine has ducts

Endocrine is ductless

Question 10

Neuro endocrine communication

Answer 10

Neural and endocrine

Question 11

cell signalling cascade

Answer 11

1. Reception
2. Transduction
3. Response

Question 12

Ligands are?

Answer 12

Hormones, local mediators, neurotransmitters…contact dependent signal molecules

Question 13

How are Ligands transported?

Answer 13

Diffuse through interstitial fluid
Blood borne transport
- free in solution (hydrophilic)
-bound to transport proteins (hydrophobic)

Question 14

Of hydrophobic Ligands, what percentage are bound?

Answer 14

NINETY NINE

Question 15

Receptors

Answer 15

Surface and intracellular

Question 16

3 main types of membrane receptors?

Answer 16

1. G protein coupled
2. Ion channel
3. Enzyme coupled (dimerising)

Question 17

What’s juxtacrine communication?

Answer 17

When cells physically touch and communicate

Question 18

Give an example of a contact dependent signal molecule that is a ligand

Answer 18

Delta

Question 19

3 main types of membrane receptors

Answer 19

1. G protein coupled receptors
2. Ion channel receptors
3. Enzyme coupled receptors