Module 2 Flashcards
Linds experiment:
an early RCT with low participants. sailors given different acidic foods to see if people would recover from scurvy
Why is establishing causal relationships important
- provides support for evidence -based practice
- epidemiology does not determine the cause of disease in individuals rather populations
- enables preventative measures to be put in place even if the cause of a disease isn’t fully understood
Bradford Hill Criteria
7 criteria to help determine if there is a causal relationship (not a checklist)
- temporality
- strength of association
- reversibility
- biological gradient
- biological plausibility of association
- consistency of association
- specificity of association
temporality - bradford hill
did cause come before disease?
Strength of association - bradford hill
RR and RD high? absence of biases (selection, confounding, information)
reversibility - Bradford hill criteria
does change in exposure change the outcome under controlled circumstances?
Biological gradient - bradford hill
does incremental increase of dose response (exposure) result in corresponding increases in outcomes?
biological plausibility - bradford hill
does it make sense biologically (ie chemicals in tobacco are carcinogenic)
Consistency of association bradford hill criteria
replication of findings. multiple studies with similar results in different environments, times, places, methods
specificity of association
a cause leads to a single effect or effect has a single cause
Epidemiological triad:
host: persons in P
Environment: physical, social, policy
Agent: biological, chemical, physical, nutritional
Causal pie - whole pie
sufficient cause- several components, minimum set of conditions for a disease to occur - without any slice, disease unlikely to occur. not a single factor. a disease can have several pies.
causal pie - component cause
a slice of the pie - a factor that contribute sot disease but not sufficient to cause disease on it’s own. includes necessary cause
necessary cause - causal pie
a component cause that must be present in the pie for a disease to occur
counterfactual causation
cause makes a difference in outcome, includes deterministic and probabilistic
probabilistic causation
cause increases the chance that effect will occur. Sufficient raise probability from 0 to 1; necessary raises from 0; each component contributes towards 0 to 1
Deterministic causation
whenever A occurs, B occurs
problems with causal pie model
- assumes all causes are deterministic
- fails to capture dose response as a continuum
Public health framework
Phase 1: define the problem
Phase 2: identify risk and protective factors
Phase 3 Develop and test prevention strategies
Phase 4: ensure widespread adoption
Causes of causes for individual:
any event, characteristic or definable entity that brings about a change for better or worse in health, like income, debt, employment, education, housing
Causes of the causes for population
similar for individuals, but nature and measurement of the determinants are slightly different. Determinants in populations are related to the context that the population exists in
Upstream
distal, a macro. government policies and trade agreements, cultural, legal, national. cause the need for proximal
distant in time or place from the change in health status
Downstream
proximal, micro. treatment and disease management
near to the change in health status
Levels of the Dahlgren and whitehead model
- individual: choices, and non-modifiable factors like age, sex, constitutional factors, and
- community and living conditions: social and community networks. Family and friends play a significant role in developing normative behaviours - what is normal and acceptable to d and experience. also the conditions you live and work in
- environment: general socioeconomic cultural and environmental conditions
habitus
lifestyle, values, dispositions, and expectations of particular social groups, learned through everyday activities
Social capital
Social capital - the value we place on our networks that facilitate bonds and change. who you know not what you know. the community environment and your role in it (ie volunteerism)
level 3 of dahlgren and whitehead - environment
- Physical: water quality, clean air, living things
- Built: design of communities, infrastructure
- Cultural: knowledge, beliefs and values
- Biological: emerging or re-emerging toxins in population
- Ecosystem: climate change, biodiversity, ecological footprint
- Political: policy and approaches to improving pophlth
Properly Built Castles Benefit Every Peasant
3 High level component of living standards frame work
- Individual and collective wellbeing: resources and life aspects important for individuals, families, communities
- Institutions and governance: the role of institutions in safeguarding and building wealth and health
- The wealth of NZ: literal wealth, but also the natural environments, and things not in an accounts
4 capitals
- Natural: environment
- Social: norms and social values, law and trust, crown-maori relationships
- Human: skills and knowledge, mental and physical health
- financial/physical: money, but also infrastructure, housing, etc.
Structure
social and physical environment conditions that influence choices and opportunities available - social factors and choices
Agency
the capacity of an individual to act independently to make free choices
SEP- socio economic position
the social and economic factors that influence what positions individuals or groups hold within a society’s structure.
objective, measurable, meaningful measurements
why measure SEP?
Quantify inequality;
highlight changes over time;
understand relationship between health and other variables;
associations between different chances in life