Module 2

Question 1

Movement of a drug from the site of administration into the body?

Answer 1

Absorption

Question 2

Fraction of administered drug that reaches systemic circulation

Answer 2

Bioavailability

Question 3

Transportation of the drug throughout the body?

Answer 3

Distribution

Question 4

The time required for the serum drug level to decrease by 50%

Answer 4

Half-life

Question 5

Process by which a drug is broken down by the body?

Answer 5

Metabolism

Question 6

Process by which a drug is cleared from the body?

Answer 6

Excretion

Question 7

Measurements of the relative safety of a drug; compares amount of a drug required for the therapeutic effect vs toxic effect?

Answer 7

Therapeutic Index

Question 8

under go a process of dissolution

Answer 8

Disintegrate

Question 9

What are the two processes a drug can be absorbed?

Answer 9

Disintegrate
Dissolve

Question 10

Factors that impact drug absorption.

Answer 10

Formulation
Concentration
Lipophilic drugs
Ph of drug

Question 11

The measured response yo time and dose
“What the body does to the drug”

Answer 11

Pharmacokinetic

Question 12

The mechanism of action or effect a drug exerts upon a drug receptor, target, or physiological process
“What the drug does to the body”

Answer 12

Pharmacodynamic

Question 13

What are the factors that limit distribution of the drug?

Answer 13

Protein binding physiological Barries for example blood brain barrier and placenta banner

Question 14

What is the number one protein binding for drugs in the blood?

Answer 14

• Albumin

Question 15

What prevents dogs for treating Parkinson’s disease from entering the brain such as dopamine?

Answer 15

Brooch brain barrier

Question 16

What is also referred to as “biotransformation”?

Answer 16

Metabolism

Question 17

What organ is the main organ responsible for drug metabolism?

Answer 17

Liver

Question 18

An inactive drug that requires A drug metabolism process to occur to be transformer into an active form?

Answer 18

Prodrug

Question 19

What common settings of reduced liven functions?

Answer 19

Neonates or promoter infants older adults and patients with liver disease such as cirrhosis

Question 20

What organ is responsible drug excretion?

Answer 20

Kidneys