Module 2 Flashcards
What equation is used for enzyme exhibiting cooperativitiy
A. Michaelis Menten
B. Hill
C. Michaelis Menten double derived reciprocal
D. All of the above
B.
if ordinary, a and c
Base on IUB system, Hexokinase is what kind of enzyme?
Transferase
How to overcome competitive inhibition
Add more substate
In non competitive inhibition, A, vmax increase, km increase B. no change vmax, km decrease C. No change vmax, no change km D. Vmax decrease, no change km
D
True or false. After a chemical rxn, enzymes are consumed.
False. Enzyme catAlyzes rxn but is not consumed or PERMANENTLY altered
True or false. Cytochrome are only found in the mitochondria
False.
If rifampicin, an enzyme inducer is given concommitantly with morphine, these will happen to morphine except
A. Inc effect
B. inc metabolism
C. Inc excretion
A. Dec
functions similar to those of prosthetic groups but bind in a transient, dissociable manner either to the enzyme or to a substrate
Cofactors
Vitamin b needed for A. NAD B. FMN C. Coenzyme A D. Ketoacids E. one carbon metabolism
A. Nicotinamide B. riboflavin C. Panthotenic acid D. Thiamine E. folic acid and cobamide
True or false. Almost all enzyme are protein
True.
Mostly protein
Some ribozymes ( RNA enzymes)
The ff can increase reaction rate except A. Increase temp B. increase reactant concentration C. Increase kinetic energy D. None of the above
D
How many hydrogen ion is translocated in NADH dehydrogenase
4
Competitive inhibition has A. No effect on vmax, increase km B. increase vmax, no effect on km C. Decrease vmax, decrease km D, increase vmax, increase km E. no effect on vmax, no effect in km
A
phosphorylation of glucose to glucose 6-phosphate is A. Endergonic B. exergonic C. Both D. Neither
A. Needs energy from ATP.
Final electron acceptor in ETC
Oxygen
If Gibbs free energy is positive, it will favor
A. Substrate formation
B. product formation
Substrate
How many hydrogen ion is needed to produce 1 ATP
4
True or false. In noncompetitive inhibition, binding of the inhibitor affects binding of substrate
False. Does not affect.
True or false. Chylomicron triacylglycerol is directly taken up by liver
False. Lipoprotein lipase must first act on it
True or false. In spontaneous rxn, there is increase in entropy
True
What is the prosthetic group of peroxidase
Protoheme
Partial oxidation of fatty acids in the liver leads to
Ketone body production
How many ATP is produced from FADH2 in TCA
3
Initial electron donor in ETC
NADH
If reaction proceeds spontaneously with loss of free energy A. Gibbs is negative, exergonic B. Gibbs is positive, endergonic C. Gibbs is negative, endergonic D. Gibbs is positive, exergonic
A
serve as recyclable shuttles—or group transfer reagents—that transport many substrates from their point of generation to their point of utilization
Co enzymes
In ETC, what links the flavoproteins to cytochrome b
Ubiquinone or coenzyme Q
process of forming glucose from noncarbohydrate precursors
Gluconeogenesis
distinguished by their tight, stable incorporation into a protein’s structure by covalent or noncovalent forces
Prosthetic group
Where do non competitive inhibitor bind
Allosteric site
If competitive, active site
True or false. Endergonic rxn does not need exergonic rxn to take place.
False. It cannot exist alone, must have energy source
In ETC the ff acts as proton pump except A. Complex I B. complex II C. Complex III D. Complex IV
B.
Uncouplers inhibit ETC by what mechanism
Create iodophores where hydrogen ions can go inside mitochondria thus reducing the electrochemical gradient for ATP synthase to occur
What inhibitor blocks conduction of hydrogen ion to the ATP synthase
Oligomycin
Monosaccharides are joined by A. Phosphodiester bond B. glycosidic bond C. Peptide bond D. Hydrogen bond
B.
phosphodiester bond for ATP
Peptide bond for amino acids
Under aerobic conditions, pyruvate enters the mitochondrion, where it is oxidatively decarboxylated to the two-carbon acetyl group in acetyl-CoA. This rxn is called
Transition rxn
How many ATP is produced in glycolysis
4
What organism utilize simple exergonic process
Autotrophs
Glucose is an example of A. Aldehyde B. ketone C. Carboxylic acid D. Alcohol
A.
Fructose is a ketone
As you go along ETC,
A. There is an increase in electronegativity
B. There is a decrease in electronegativity
C. There is no change in electronegativity
A
In ETC, an inhibition of 1 complex will A. Slow down ETC B. Stop ETC C. Hasten ETC D. No effect
B
Lower Km will result to A. Increase affinity B. increase vmax C. Decrease affinity D. Decrease vmax
A
How many net ATP is produced in aerobic glycolysis
7
Most important carbohydrate
Glucose