MODULE 1.4 RESPIRATION Flashcards

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0
Q

Outline reasons why living organisms need to respire

A

-protein synthesis, synthesis of cellulose from beta glucose
-exocytosis and endocytosis
-active transport across plasma membranes against conc gradient
-movement I.e bacterial flagella, muscle contraction
-

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1
Q

What is respiration.

A

Process where energy that I stored in complex organic molecules is broken down to make ATP

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2
Q

What is the structure of an ATP molecule

A

Made of adenosine (adenine and ribose) and 3 phosphate molecules

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3
Q

What is an anabolic reaction

A

Synthesis of larger molecules from smaller ones in biochemical reactions

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4
Q

What are catabolic reactions

A

Hydrolysis of larger molecules into smaller ones

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5
Q

Why are coenzymes needed

A

Normal enzymes good at catalysing metabolic reactions but not at reactions involving oxidation and reduction

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6
Q

What is NAD

A

Organic non protein molecule that helps dehydrogenase enzymes do oxidation reactions
Made of TWO linked nucleotides
One containing nicotinamide ring, phosphate and ribose and the other containing adenine, phosphate and ribose

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7
Q

What does the nicotinamide ring on one of the NAD molecules do

A

Accepts hydrogen atoms that are later split into hydrogen ion and electron

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8
Q

How does NAD work

A

Accepts hydrogen atoms with electrons and becomes reduced and when it loses it becomes oxidised

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9
Q

Define glycolysis

A

The breakdown of a hexose(glucose) sugar into 2 pyruvate molecules and occurs in the cytoplasm of all cells
Common in aerobic and anaerobic respiration

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10
Q

What is the structure of coenzyme a and how does it work

A

Made of adenosine, 3phosphate groups, cysteine and pantothenic acid
Carries acetate groups made during link reaction onto krebs cycle and acetate groups made from some fatty or amino acids

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12
Q

What are mitochondria?

A

They are organelles found in eukaryote cells– site for link reaction Krebs cycle and oxidative phosphorylation

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13
Q

What is the ultrastructure of mitochondria

A

– It has an outer and inner membrane which make up the envelope

  • outer membrane smooth and inner folded into cristae for large surface area
  • inner membrane has matrix which is semi rigid and gel like
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14
Q

What happens in the matrix and How does the structure of the matrix allow it to carry out its functions

A

Links reaction and krebs cycle

  • contains enzymes that catalyse these reactions
  • NAD
  • oxaloacetate
  • mitochondrial DNA which may code for proteins and mito enzymes
  • mito ribosomes
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15
Q

How does glycolysis happen

A

-phosphorylation whereby ATP is hydrolysed and phosphate produced added onto glucose and carbon 6 causing fructose 6 phosphate
Another ATP hydrolysed added at first carbon making fructose 1,6 biphosphate, molecule now unstable
-this split into 2 molecules of trios phosphate
-trios p oxidised: 2 h atoms removed aided by dehydrogenase enzymes and NAD : 2 mol of NAD reduced and 2 mol of ATP formed
-triose phosphate converted to pyruvate and 2 mol of ATP formed

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16
Q

define mitochondria

A

organelles found in eukaryote cells

17
Q

describe the structure of mitochondria

A
  • inner and outer phospholipid membrane e.g envelope
  • outer smooth and inner folded into cristae with ATP synthase and electron carriers
  • matrix enclosed by inner membrane
18
Q

what happens in the link reaction

A
  • decarboxylation and dehydrogenation of pyruvate to acetate
  • NAD accepts hydrogen and co enzyme a accepts acetate to carry to krebs reaction
  • takes place in mitochondrial matrix
19
Q

how does lactate fermentation occur

A

reduced NAD is reoxidised by lactate dehydrogenase and pyruvate accepts the H+ ions
NAD+ can then go on to accept more h+ ions so enough ATP is produced by substrate level phosphorylation in glycolysis

20
Q

what happens to lactate once lactate fermentation has occured

A

is carried in the blood to liver cells where it can be reoxidised to pyruvate once enough oxygen is available so can enter link and krebs
or can be recyles to glucose and glycogen

21
Q

what happens in alcoholic fermentation

A

pyruvate decarboxylated to ethanal (pyruvate decarboxylase)
ethanal accepts h+ ions from RNAD which becomes ethanol (ethanol dehydrogenase)
reoxidised NAD can now accept more h+ from glucose