Module 1 : Fertility and sexual health Flashcards
Trichomonas
Signs (4)
Offensive, yellow/green, frothy discharge
Vulvovaginitis
Strawberry Cervix
pH >4.5
Asymptomatic usually in men, may cause urethritis
Trichomonas
Ix
Treatment
Ix - microscopy shows motile trophozoites
Tx - Oral metronidazole 5-7 days or 2g STAT
Bacterial Vaginosis Amsels Criteria (4)
3 of 4 for diagnosis Thin white homogenous discharge Clue cells on microscopy pH >4.5 Positive wiff test - fishy with potassium hydroxide
BV - Organism
Garderella Vaginalis overgrowth - leads to fall in lactic acid producing aerobic lactobacilli
BV
Tx
Cure rate, Relapse rate
Oral metronidazole 5-7 days
70-80% cure, >50% relapse in 3 months
BV risks in pregnancy
Increased risk of.. Preterm labour Low birth weight Late miscarriage Chorioamnionitis
Candida
Signs (4)
Cottage cheese, non offensive
Itch
Vulvitis - superficial dyspareunia, dysuria
Vulval erythema, fissuring, satellite lesions
Risk factors for Candida
DM, steroids, Abx, pregnancy, immunosuppression
Treatment for Candida
Local - clotrimazole pessary 500mg PV
Oral - Itraconzaole, Fluconazole
Pregnancy - oral CONTRAINDICATED
Recurrent Candida
Definition and Management
4 or more episodes per year
Do HVS to confirm, bloods ? DM, exclude lichen sclerosus
Induction: Fluconazole every 3 days for 3 doses
Maintenance: Fluconazole weekly 6 months
HPV strains
Genital Warts
Cervical Ca
Genital Warts 6,11
Cervical Ca 16,18
Cervical screening ages
25-49 3 yearly
50-64 5 yearly
Can be delayed 3 months post partum
HPV negative screen
Return to recall unless on treat till cure, untreated CIN1 or follow up
HPV positive and cytology normal
Repeat at 12 months
- if -ve routine
- if +ve repeat again in 12 months and if + again COLPOSCOPY
HPV positive cytology abnormal
Colposcopy
Cervical smear inadequate sample
Repeat in 3 months
2x inadequate go to COLPOSCOPY
Risk factors for Cervical Ca
HPV 16,18,33 Smoking HIV Many sexual partners High parity COCP
How do HPV 16 and 18 work
16 - produces E6 oncogene which inhibits p53 tumour suppressor
18 - produces E7 oncogene which inhibits RB suppressor
FIGO Cervical Ca
1A
Confined to cervix
Less than 7mm wide
A1 = <3mm deep
A2 = 3-5mm deep
FIGO Cervical Ca
1B
Confined to cervix
Visible or larger than 7mm
B1 = <4cm diameter
B2 = >4cm diameter