Module 1 Flashcards

Introduction to Physiology: Regulation & Mechanisms

1
Q

What is physiology?

A

The study of how cells, tissues, organs, and systems function in living organisms.

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2
Q

Define Homeostasis.

A

The dynamic constancy of physiological variables despite external changes.

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3
Q

Name the three type of muscle cells

A

Cardiac, skeletal, and smooth muscle cells.

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4
Q

What is the main function of epithelial cells?

A

Selective secretion, absorption, and protection.

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5
Q

Describe a negative feedback mechanism.

A

A process where a change in a variable is countered to return to a set point.

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6
Q

Give an example of positive feedback.

A

Blood clot formation.

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7
Q

What are the components of a reflex arc?

A

Stimulus, receptor, afferent pathway, integrating centre, efferent pathway, and effector.

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8
Q

What is feedforward regulation?

A

Anticipatory changes in physiological processes to maintain stability.

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9
Q

What is the role of hormones in intercellular communication?

A

Hormones are chemical messengers that travel through the bloodstream to affect distant cells.

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10
Q

Define gap junction communication.

A

Direct transfer of molecules between adjacent cells via cytosol linkages.

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11
Q

What is a circadian rhythm?

A

A biological cycle that repeats approximately every 24 hours.

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12
Q

How does heatstroke relate to homeostasis?

A

Disruption of homeostasis due to excessive heat leads to failure in temperature regulation and hydration balance.

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13
Q

What are the three main types of connective tissue?

A

Loose connective tissue, dense connective tissue, and specialized connective tissues like blood, bone, and cartilage.

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14
Q

Differentiate between simple and stratified epithelium.

A

Simple epithelium is one cell layer thick; stratified epithelium has multiple layers.

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15
Q

What are the two primary functions of the extracellular matrix (ECM)?

A

It provides structural scaffolding for cells and transmits information via chemical messengers to regulate cellular activities.

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16
Q

Name two types of fibers found in the ECM.

A

Collagen fibers and elastin fibers.

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17
Q

What distinguishes pathophysiology from physiology?

A

Physiology refers to maintaining homeostasis, while pathophysiology occurs when homeostasis fails.

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18
Q

What is dynamic constancy in homeostasis?

A

Physiological variables fluctuate within a range but remain relatively constant over time.

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19
Q

Why does positive feedback not regulate physiological variables?

A

It amplifies changes, moving a system further from equilibrium.

20
Q

What is the role of an effector in a reflex arc?

A

It carries out the response to restore homeostasis.

21
Q

How is feedforward regulation different from feedback mechanisms?

A

Feedforward regulation anticipates changes and adjusts before they occur.

22
Q

Provide an example of an organ system and its components.

A

The urinary system includes the kidneys, ureters, bladder, and urethra.

23
Q

What tissues can compose an organ?

A

An organ can include epithelial, connective, muscle, and nervous tissues.

24
Q

What is the difference between plasma and interstitial fluid?

A

Plasma is the fluid portion of blood, while interstitial fluid surrounds cells in tissues.

25
Q

What is the total extracellular fluid composed of?

A

Plasma and interstitial fluid.

26
Q

How do biological rhythms support homeostasis?

A

They prepare the body for predictable changes, enabling faster homeostatic responses.

27
Q

What is the difference between adaptation and acclimatization?

A

Adaptation is a genetic trait for survival, while acclimatization is a physiological adjustment to environmental changes.

28
Q

What distinguishes paracrine signaling from endocrine signaling?

A

Paracrine signaling acts on nearby cells, while endocrine signaling acts on distant cells through the bloodstream.

29
Q

How does juxtacrine signaling differ from other types of communication?

A

It requires direct contact between adjacent cells.

30
Q

What are the three states of total-body balance for chemical substances?

A

Negative balance (loss > gain), positive balance (gain > loss), and stable balance (gain = loss).

31
Q

Why is the “pool” concept important in physiology?

A

It represents the dynamically regulated concentration of substances like glucose in the body.

32
Q

What is the dual role of glands in homeostatic reflexes?

A

Glands can act as receptors and integrating centers while secreting hormones as effectors.

33
Q

Why can norepinephrine function as both a hormone and a neurotransmitter?

A

Its effects depend on its mode of release and the target it acts on.

34
Q

In the case of heatstroke, why did the man stop sweating?

A

The body’s thermoregulatory mechanism failed, disrupting homeostasis.

35
Q

How does fainting relate to disrupted homeostasis?

A

Low blood pressure and dehydration impaired the body’s ability to deliver oxygen and nutrients to tissues

36
Q

The surprise of a phone call at 3:00 am results in an increase in heart rate. This is an example of a

A

acute change.

37
Q

If an animal permits internal and external conditions to be equal, it is said to show ————-.

A

conformity

38
Q

Rainbow trout captured and brought into a lab aquarium undergo a chronic adjustment to the conditions in the lab. This process is called ————–.

A

acclimation

39
Q

During childbirth, muscular contractions acting to expel the fetus from the uterus induces hormonal signals that induce even more intense contractions. This is an example of ———-.

A

positive feedback.

40
Q

Most of the fluid in the body is located in the

A

Intracellular compartment

41
Q

How do nonpolar molecules diffuse through the hydrophobic portions of the cell membrane?

A

Nonpolar molecules diffuse through the membrane because they can dissolve in the fatty acid tails of the lipid bilayer.

42
Q

A paracrine is a chemical factor released by cells that acts on neighboring cells by —–

A

Diffusing through the extracellular fluid, without entering the bloodstream.

43
Q

What are the functions of cholesterol molecules within a cell membrane?

A
  1. To limit the ordered packing of fatty acids, maintaining membrane fluidity.
  2. To form lipid rafts, which are specialized membrane regions.
    3.To participate in intracellular signaling.
44
Q

What are parts of the desmosomes ?

A
  1. Dense plaques proteins.
  2. Cadherins.
  3. Keratin.
45
Q

What is the difference between saturated and unsaturated fatty acids in phospholipid tails?

A
  1. Saturated fatty acids: Contain no double bonds between carbon atoms and are fully saturated with hydrogen atoms, resulting in straight tails.
  2. Unsaturated fatty acids: Contain one or more double bonds between carbon atoms, leading to bends of approximately 30 degrees in the tail.