Module 1 Flashcards

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1
Q

What is sexual reproduction?

A

Involves the meeting of gametes which carry genetic information from both parents to the offspring.

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2
Q

Advantages and disadvantages of sexual reproduction:

A

+) some offspring may possess random variations that make them better suited to new and changing environmental conditions. They may out-compete other individuals in the population, thus gaining a selective advantage. This survival gives the overall population a better chance of survival.
-) process demands a greater expenditure of time and energy, involving processes such as finding a mate, courtship behaviour, game production and mating. These processes may also make organisms vulnerable to predators.

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3
Q

Define asexual reproduction:

A

Involves only one parent and gives rise to genetically identical offspring

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4
Q

Advantages and disadvantages of asexual reproduction:

A

+) fast, good in stable, unchanging environments
-) bad for changing environment/disease due to no genetic variation

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5
Q

What is external fertilisation?

A

Involves the fusion of a sperm and ovum outside the female body.
- better suited to organisms that produce in aquatic or very moist environments
- less time and energy are required of the parents, but a large number of gametes must be produced to ensure that some young survive

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6
Q

Advantage of external fertilisation:

A

Wide dispersal of young; some marine animals release their gametes into the sea, and the fertilised eggs are carried far away from their parents to reduce competition for food, living space, and allows rapid recovery of populations in damaged areas.

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7
Q

Examples of external fertilisation:

A
  • Bony fish: produce ova in large batches and release them into the water where they fuse with the sperm outside the female body. Although thousands of eggs are fertilised, many succumb to microbial infection or predators
  • Amphibians: in frog and toad copulation, the male grasps the female and straddles her back, discharging fluid containing sperm onto the eggs as they are released by the female into the water.
  • Staghorn coral
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8
Q

What is internal fertilisation?

A

Involves the fusion of gametes inside the female body.
- protects gametes from dehydration and loss to external elements, and protects fertilised eggs and developed young from immediate predation, therefore fewer eggs are required for the survival of a sufficient number of offspring

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9
Q

Examples of internal fertilisation:

A
  • Reptiles: most reptile eggs are fertilised internally and then deposited outside the mother’s body for development
  • Birds: male and female birds rub the openings of their cloacas together and sperm are transferred to the females body
  • Mammals:
    Monotremes (e.g. platypus): after internal fertilisation, they lay eggs that develop outside the mother’s body
    Marsupials: develop internally for a short time after fertilisation and then continue their embryonic development in a pouch
    Eutherians (placental mammals): following internal fertilisation, the young completes its embryonic development inside the body of the mother in the uterus, which nurtures and protects the embryo.
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10
Q

Similarities of internal and external fertilisation:

A

Sim: male and female gametes are required, zygote requires a watery environment for development, if male and female gametes are in close proximity to each other, fertilisation will occur.

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11
Q

Differences of internal and external fertilisation:

A

Gametes: In Ex large number of male and female gametes are produced, where In has large number of male gametes but fewer female gametes produced.

Conception mechanism: in EX there is a simultaneous release of gametes, in IN the male inserts sperm into the female’s reproductive tract

Chance of fertilisation: in EX it is low as male gametes are released into a large open area less successful with uniting with female gametes, in IN it is high a male gametes are released into a confined space with more change in successfully uniting with female gametes.

Environment for zygote: in EX usually external, watery environment, vulnerable to temp, predation and infection. in IN usually internal, protected environment inside female’s body with less chance of predation, infection.

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12
Q

How does fertilisation occur in a sexually reproductive plant?

A

The male gametes inside the pollen must be carried from the anthers to the stigma, process called pollination. Once pollen has been deposited on the stigma, a pollen tube germinates and grows down the style to an ovule contained in the ovary. In flowering plants, fertilisation occurs internally inside the ovary.

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13
Q

Differentiate between self-pollination and cross-pollination:

A

Self pollination in plants requires less energy as there is no requirement for the plant to produce structures to attract pollinators. The plants can grow in areas where insects/animals that visit plants are absent/few.
Cross pollination relies on outside agents to transfer pollen from anthers to stigmas; this may be abiotic agents (wind, water) or biotic agents (insects, animals). Cross pollination ensures greater variation in the offspring.

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14
Q

Features of pollination by wind:

A
  • anthers are long and produce large amounts of light pollen, easily picked up by the wind
  • stigma are very large and spread out in a feathery manner to trap pollen carried by wind
  • wind pollination is inefficient, so large quantities of pollen are produced
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15
Q

Pollination by animals:

A

During the search of animals finding nectar, pollen rubs onto their bodies and then transferred to the next flower they visit. Flower scent, colour, shape and nectar are important in attracting animals.

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16
Q

What is seed dispersal?

A

After pollination and fertilisation of the flowers of a plant, seeds from inside the ovary are dispersed.
+) seeds are dispersed over a wide distance, this helps prevent overcrowding and competition for light, water and soil nutrients. Widespread distribution also increases chances of continuity of the species in other locations in case there is a sudden change in the local environment.

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17
Q

What is asexual reproduction? Advantages + disadvantages:

A

Does not involve production or fusion of gametes, offspring is genetically identical to the parent, no mixing of genetic information to introduce variation. This is the main form of reproduction in unicellular organisms.
+) enables organisms to reproduce quickly without having to find a mating partner as it can be complicated if they are immobile. Also comp. advantage if they live in an environment which they are well adapted to.
-) little or no variation in a population makes the whole group vulnerable to sudden changes in the environment, affecting survival.

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18
Q

What is vegetative propagation?

A
  • 1 parent, mitosis, no genetic variation
    New individuals arise from portions of the roots/stems/leaves/buds of adult individuals and are genetically identical to their parent
  • used in agriculture to increase the production of crops when seeds are difficult to germinate
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19
Q

Examples of vegetative propagation:

A
  • runners: long thin modifies stems that grow along the surface of the soil (lateral shoot)
  • rhizomes: underground horizontal modified stems
  • suckers: lateral root, the root produces modified roots which gives rise to new plants and can spread quickly into a vacant patch of habitat after disturbance
  • tubers: fast, good at colonising new land, stable environment, however bad bc there is comp with parent plant, no variation
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20
Q

What is budding?

A

An adult organism gives rise to a small bud which separates from the parent and grows into a new individual.
- when environmental conditions are favourable, a small outgrowth develops of the parent cell. As this outgrowth enlarges, the parent cell replicates its DNA, the nucleus divides and one copy moves into the bud/daughter cell. When the daughter cell reaches a certain size, it detaches from the parent cell and continues to grow until it buds in turn.
+) if there is no variation in the environment, the identical offspring will always be adapted to their surroundings
-) if the environment changes, the entire species may rapidly decline and die out

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21
Q

What is binary fission?

A

Main method of asexual reproduction in unicellular organisms such as bacteria and protists. A newly divided cell grows to twice its size, replicates its DNA, and then splits into 2 cells with identical genetic material.
- in prokaryotes (bacteria) there is no mitosis because there is no nucleus
in unicellular organisms (protists) it will involve mitosis

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22
Q

What is asexual reproduction in bacteria? (binary fission in specific detail)

A

A cell grows to twice its size, DNA replicates and separates, protein accumulates at the cleavage site, the cytoplasm divides and a new wall is synthesises.

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23
Q

How is binary fission and budding similar?

A

Both involve one parent, so no mate is required, allowing rapid proliferation of genetically identical organisms that are well suited to survive in their particular environment.

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24
Q

Features of spores:

A
  • tiny unicellular reproductive cells produced in great numbers
  • sporangia produces large number of spores which are light and easily dispersed, travelling long distances by wind. Spores effectively expand the distribution of the species and are able to colonise new environments.
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25
Q

How does mammals have sexual reproductive mechanisms to maximise reproductive success?

A
  • internal fertilisation increases the likelihood that gametes will meet
  • implantation of the embryo into the uterine wall with internal development of the embryo increases the embryo’s chance of survival
  • pregnancy allows the developing young to be protected from the external environment, having constant supply to nutrients.
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26
Q

What are hormones?

A

Chemical substances (protein) that act as messengers in the body, coordinating body functions so that actions are synchronised, which is secreted by the pituitary gland.

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27
Q

Advantages of seasonal breeders and continuous breeders:

A

Seasonal breeders is when their hormones regulate their sexual behaviour by limiting the mammal to reproduce at certain times of the year. Offspring is usually born when temp is warm and food is plentiful, thus increasing the chance of offspring survival. Also the parents benefits from reduced period of time during mating and gestation which takes up energy and makes them more vulnerable to predators.
Continuous breeders is when female fertility occurs in a cycle that repeats throughout the year, positie as it allows them to reproduce all year round.

28
Q

What are the 3 types of sex hormones?

A
  • androgens
  • oestrogens
  • progestogens
29
Q

What is androgen?

A

Hormone that controls the development and functioning of male sex organs and secondary sex characteristics. Cells in the testes secrete the androgen testosterone, which plays a primary role in spermatogenesis (production of sperm).

30
Q

What is oestrogen?

A

Hormone that controls the development and functioning of the female reproductive system and secondary sex characteristics (breasts, pubic hair). In males oestrogen plays a role in the maturation of sperm. The main function of oestrogens in mammalian production is ovarian functioning and therefore fertility in females.

31
Q

What is progestogen?

A

Progesterone is the most common progestogen and it plays a primary role in pregnancy, and also stimulates the decretion of milk in mammary glands.

32
Q

Hormone production steps:

A

1) Gonadotrophic-releasing hormone stimulates anterior lobe cells to secrete follicle-stimulating hormone and luteinising hormone.
2) In ovary FSH and LH promote follicle growth and oocyte maturation, oestrogen production, priming the endometrium and initiating other reproductive events
3) blood level of oestrogens rises, stimulating a surge in LH secretion
4) mid-cycle surge of LH triggers ovulation, then formation of corpus luteum
5) progesterone (and small amounts of oestrogen) secreted by corpus luteum maintain the endometrium if pregnancy occurs
6) increase in progesterone, oestrogen in blood inhibits FSH, LH secretion during last phase of cycle

33
Q

How does oestrogen and progesterone produced by the ovaries and controlled by hormones of the pituitary, regulate the ovarian cycle and menstrual cycle?

A

Regulates ovarian cycle by controlling the production and maturation of gametes in the ovaries. Regulates menstrual cycle by preparing the uterus for implantation of a fertilised egg each cycle, if fertilisation does not take place, the levels of oestrogen and progesterone decrease and the lining of the uterus tears away with bleeding (known as menstruation)

34
Q

What is the follicle stimulating hormone (FSH) and the luteinising hormone (LH)

A

FSH is important for stimulating maturation of follicles in the ovaries of females.
LH promotes final maturation of the ovarian follicle, ovulation and development of the corpus luteum in females.

35
Q

Stages in the ovarian and menstrual cycles:

A

Menstruation (days 1-4): uterine bleeding, accompanied by sheeding of the endometrium
Pre-ovulation (days 5-12): endometrial repair begins; development of ovarian follicle, uterine lining gradually thickens
Ovulation (days 13-15): rupture of mature follicle, releasing egg
Secretion (days 16-20): secretion of watery mucus by g;ands of endometrium, cervix and uterine tubes; movement and breakdown of unfertilised egg, development of corpus luteum
Pre-menstruation (days 21-28): degeneration of corpus luteum; deterioration of endometrium

36
Q

What does spermatogenesis in humans involve?

A

Involves the interaction of the hypothalamus, the pituitary gland and the Leydig cells (in testes). In males, LH stimulates the production of testosterone and FSH stimulate the production of Sertoli cells in the testes, to maintain testosterone at a level high enough to promote spermatogenesis. When the hormone inhibin is secreted, it reduces the levels of FSH in the body.

37
Q

What is the presence of corpus luteum during pregnancy?

A

Once the embryo implants, the corpus luteum in the ovary continues to grow and secreted hormones for the first 3 months of pregnancy, in the latter 6 months of pregnancy, the corpus luteum shrinks and degenerates slowly. If the egg is not fertilised, the corpus luteum begins to degenerate 8-10 days after ovulation.

38
Q

Role of progesterone after implantation has occurred:

A

Suppressing uterine activity, thereby supporting foetal development and reducing the risk of the foetus being disturbed or expelled by uterine contractions. Progesterone also reduces the mother’s immune response to foetal antigens.

39
Q

What is mitosis?

A

Is the nuclear division of eukaryotic cells for asexual reproduction, and for growth and repair in multicellular organisms.

40
Q

Importance and role of mitosis?

A

Cell division
- growth of multicellular organisms
-repair of damaged tissue and replacement of worn-out cells
- asexual reproduction

41
Q

What is meiosis?

A

Type of cell division that occurs in the sexual reproductive organs of a plant/animal and it results in the formation of gametes, also introduces genetic variation into a population. In meiosis I, the diploid cell divides into two haploid cells, in meiosis II, the two cells divide each again resulting in four haploid daughter cells.

42
Q

What are the 4 main phases in the cell cycle?

A

-> G1 is a gap phases before DNA replication, during this phases cell enlargement takes place, and cellular contents excluding the chromosomes are duplicated.
-> S is a synthesis phase during which DNA replicates
-> G2 is a second gap phase after replication, when enzymes in the cell check the duplicated chromosomes for any errors and make any needed repairs
-> Mitosis is when the nucleus divides, followed by cytokinesis where the division of the cytoplasm separates one cell into two.

43
Q

Features of interphase:

A
  • occurs in the S phase of the cell cycle, where DNA synthesis occurs
  • DNA replicated and appears spread out in chromatin
44
Q

Features of prophase:

A
  • chromatin material shortens and thickens by coiling
  • nuclear membrane begins to break down and is no longer visible
  • spindle fibres begin to form
45
Q

Features of metaphase:

A
  • chromosomes line up across the centre of the cell, each attached to the spindle fibres by a centromere
46
Q

Features of anaphase:

A
  • proteins in the centromere are cleaved allowing sister chromatids to separate, Spindle fibres contract and the chromosomes are pulled by their centromeres to opposite ends of the cell.
47
Q

Features of telophase:

A
  • spindle fibres break down now that daughter chromosomes are at opposite poles of the cell
  • nuclear membranes assemble around the two nuclei
48
Q

Features of cytokinesis in animal and plant cells:

A

Division of the cytoplasm occurs forming two daughter cells.
- animals cells: the cytoplasm construct in the centre of the cell between the two daughter nuclei and ‘pinches off’
- plant cells: a cell plate forms, cellulose is then deposited on either side, forming a cell wall to separate the two daughter cell

49
Q

What are the 3 types of RNA?

A
  • messenger RNA: involved in carrying information from DNA, transporting a transcribed copy from the nucleus to the cytoplasm
  • ribosomal RNA: brings mRNA and tRNA together during translation
  • transfer RNA (tRNA): assists in translating the mRNA message into proteins
50
Q

Features of a DNA molecule:

A
  • each DNA molecule is made up of two antiparallel strands, nucleotides can only be added in the 3’ direction
  • each strands is made up of a sequence of nucleotides held together by weak hydrogen bonds
  • advantage of weak hydrogen bonds is that little effort is required to pull the bases apart so that DNA can replicate
51
Q

What is the process of DNA replication?

A

1) The DNA double helix unwinds: Helicase causes the DNA helix to unwind and strands separate
2) DNA unzips - the two strands separate: Weak hydrogen bonds break catalysed by DNA helicase, creating a replication fork. Single stranded binding proteins bind to stabilise the newly separated single-stranded DNA
3) Nucleotides are added against each single strand: each seperate strand of DNA acts as a template for the production of a new strand of DNA. The primer is made and attaches to the DNA for synthesis to be initiated. DNA polymerase II adds DNA nucleotides to continue the synthesis of the new strand by picking up free floating nucleotides and attaching them to complementary base pairs.
4) replication errors are identified and corrected: DNA polymerase I proof reads the strand and corrects any errors. Ligases seals together the two new strands.

52
Q

What is the leading strand and the lagging strand?

A

The leading strand is where nucleotides are added in a log chain, growing in the same direction as the replication fork opens up, replication is continuous.
The lagging strand is where nucleotides are added in Okazaki fragments, from the replication fork backwards. Replication in this strand is discontinuous.

53
Q

Why is accurate DNA replication important?

A

Heredity - the genetic material of a cell must be transmitted accurately from:
- one cell to another during mitosis, allowing growth, repair and maintenance of an organism
- one generation to another during meiosis
Gene expression - the genetic material of a cell must be transmitted accurately to give the correct instructions to a cell to ensure the correct structure, functioning and behaviour of an organism

54
Q

What does continuity of species mean?

A

Refers to the ongoing survival of species as a result of characteristics being passed from parents to offspring in a continuous lineage. This inheritance of characteristics relies of passing accurate genetic information and the occasional introduction of variation of some genetic information so that species can adapt and survive in changing environments.

55
Q

What are the mechanisms that result in genetic variation in species?

A

Mutation -> changes in DNA due to mutation may be spontaneous or mutagen-induced
Mixing of parental genes during sexual reproduction -> through crossing over and independent assortment in meiosis, and random fertilisation in gametes

56
Q

Errors in replication:

A
  • spontaneous mutations: natural errors that arise randomly during DNA replication
  • Mutagenic mutations: errors that arise as a result of exposure of cells to environmental factors such as radiation or chemicals
57
Q

What does genetic continuity rely on?

A
  • consistent replication of genetic information that is passed from a parent ell to daughter cells, resulting in continuity in the traits being passed from parents to offspring
  • the effect of natural selection and evolution on the gene pool as a result of:
    -> introduction of variation during sexual reproduction
    -> random errors arising by mutation, being replicated and passed on to offspring
58
Q

What is transcription?

A

Transcription does not copy, it synthesises a complimentary strand.
Occurs when RNA polymerase binds to a section of DNA and begins building a chain of RNA nucleotides to form a complementary strand of RNA. The non-coding strand of the DNA acts as a template and RNA nucleotides form a complementary single stranded RNA molecule. The sequence of nucleotide bases on the mRNA molecule is the same as the DNA coding strand except it has U instead of T. The mRNA moves out of the nucleus and into the cytoplasm.

59
Q

What is translation?

A

Occurs when the ribosomes move along the mRNA molecule and attach tRNA molecules to mRNA by temporarily pairing the bases of the tRNA anticodons with the codons on the mRNA. The amino acids from the tail end of each tRNA are linked to one another by an enzyme to form a polypeptide chain. The tRNA then moves into the cytoplasm to pick up a new amino acid.

60
Q

Differentiate between transcription and translation:

A

Transcription occurs when the double helix DNA unzips and a single strand of mRNA is made using part of the non-coding strand of a DNA molecule as a template. Translation occurs when mRNA is ‘read’ by ribosomes and translated into a polypeptide, with the help of tRNA.

61
Q

What are introns and exons?

A

Exons (2%) are expressed, they code for a polypeptide. Introns and intervening sequences and are removed before translation (98%).

62
Q

What is post-transcriptional modification?

A

Removes introns (98% of DNA), exons get joint together to make a protein. Sometimes introns may have an off/on switch right next to an exon, a mutation switches on a gene which shouldn’t be on. Mutations in exons are more serious as it will code for the wrong amino acid.

63
Q

Hiercharial protein structure:

A

1) amino acids
2) helix
3) folding of the polypeptide chain
4) assembled sub units (proteins joint together) -> not all proteins

64
Q

What does it mean?
Gene:
Redundancy:

A

Gene is the structural and functional unit of inheritance; a sequence of DNA carried on a chromosome in eukaryote and processed to produce a polypeptide.
Redundancy: multiple codons code for the same amino acids

65
Q

Define variation:

A

the difference in characteristics evident between individuals (observed differences)

66
Q

Define variability:

A

the different forms of a gene within a population; the total of all the alleles present in the gene pool of a population

67
Q

Autosomal inheritance:

A

1) law of segregation - each allele for a trait must randomly segregate into gametes of an organism
2) Law of Independent Assortment - alleles for different characteristics separate and are passed on independently of one another
3) Law of Dominance - when there are different alleles in a pair (heterozygous genotype) one alleles will be expressed while the other will be hidden.