Module 1 Flashcards
Kidney Theory; Infection Control; Hemodialysis Process, System & Devices
What are the four transport mechanisms that play a role in hemodialysis?
Ultrafiltration, Convection, Diffusion, and Osmosis
What is Ultrafiltration?
Fluid is pushed through a semipermeable membrane
What is Convection?
Solutes or particles pulled across a membrane by water movement
also known as Solute Drag
What is Diffusion?
Solutes moving from an area of higher concentration to an area of lower concentration.
What is Osmosis?
The movement of water across a membrane to equalize solute concentrations, from an area of low concentration to an area of high concentration.
What are the kidney’s excretory functions?
To normalize electrolytes, remove wastes, and provide fluid & acid base balance.
Allows body to maintain homeostasis.
How do we replace normal excretory kidney functions?
By utilizing a dialyzer or “Artificial Kidney”
What is the function of bicarbonate in the dialysate solution?
Bicarbonate acts a buffer to the Acid
What is the function of bicarbonate when it diffuses into the patient’s blood?
Prevents patient’s blood pH from dropping to dangerous levels during treatment.
What percent of dialysate is purified water?
90%
What is the formula for Venous Pressure?
Venous Pressure (VP) = Filter Pressure + (Return Pressure/2)
What does TMP stand for?
Transmembrane Pressure
What is the Formula for TMP?
TMP= Venous Pressure (VP) - Dialysate Pressure
What does the Acid Concentrate contain?
Sodium (Na+), Magnesium (Mg+), Acetate(C2H3O2-), Chloride (Cl-), Dextrose (C6H12O6)
What is the function of the acid concentrate?
Adds electrolytes in precise amounts.
Is necessary to prevent calcium and magnesium from precipitating out of the bath.
(Precipitation: solute particles find each other and form a solid together)
What does Target Weight mean?
Post-dialysis weight that patient can safely & reasonably achieve after dialysis.
Decided on by Nurse & Patient for each treatment as to the amount of fluid to be removed
What does hemodialysis do?
Helps to normalize body pH through diffusion of bicarbonate from the dialysate into the blood.
What is eliminated through the dialyzer fibers by diffusion?
Blood Urea Nitrogen (BUN) & Creatine
What is BUN?
Blood Urea Nitrogen
Waste products from protein metabolism
What is Creatine?
Waste products from muscle metabolism
What are signs and symptoms of Hyperkalemia?
Potassium (K+) electrolytes are too high
>5.5mEq
Weakness, slow heartbeat, cardiac arrest
What are signs and symptoms of Hypokalemia?
Potassium (K+) electrolytes are too low
<3.5mEq
Cardiac Arrhythmias
What is the normal blood pH range?
7.35-7.45
What are the kidney’s endocrine functions?
Renin secretion, Erythropoietin secretion, Vitamin D activation
What is Vitamin D activation?
Decreased serum calcium levels –> kidneys convert Vitamin D3 into active form Calcitriol –> Calcitriol stimulates absorption of dietary calcium & phosphorus from the gut (small intestine)
How do we replace normal endocrine kidney functions?
Provide Medications
What is the lifespan of a red blood cell?
120 days
What is the Criteria for Chronic Kidney Disease (CKD)?
Abnormalities of kidney structure or function > 3months, w/ health complications
Duration >3 months based on Doctor evaluation & documentation (from Acute to CKD)
How much of normal kidney function is replaced by hemodialysis?
15%
3-4 hours, 3x a week
What can happen to patients who do not get enough dialysis?
They can develop uremic symptoms
What is Uremia and how does it affect the body?
Buildup of wastes in the blood due to kidney failure and affects all body systems
What is Uremic Syndrome?
signs and symptoms that result from toxic effects of elevated Nitrogenous and other wastes in the blood.
Symptoms progress slowly and affect all body systems
Symptoms & Signs: Edema, itching, flu like symptoms (nausea, muscle aches ,vomiting, poor appetite)
Other signs or symptoms: Hypertension, anorexia, restlessness, dyspnea, shortness of breath, fatigue, weakness, Xerosis, pseudoporphyria
What is Pseudoporphyria?
a rare skin condition that causes blistering and skin fragility in areas of the body exposed to sunlight
What are the most common causes of CKD in the USA?
Diabetes
Hypertension
Polycystic Kidney Disease
Outline the treatment goals for a patient with CKD
Slowing the progression of CKD
Managing comorbidities and complications
Controlling symptoms
Minimizing the effects of CKD on patients’ lifestyles
Kidney replacement therapy modality education
Encouraging patients to actively participate in their healthcare
What are Pre-Renal Causes of CKD
Prolonged shock, very low blood pressure, injury w/ significant blood loss, Massive internal bleeding, narrowing of arterial vessel.
What are Intrarenal Causes of CKD
Diabetes mellitus, hypertension, drugs/medication, Polycystic kidney disease (hereditary), LUPUS, Sickle cell anemia, Glomerulonephritis
What are Post-Renal Causes of CKD
Kidney stones, tumor in bladder, stenosis, enlarged prostate
Irreversible & Permanent
What are the stages of CKD
Stage 1: GFR = 90+
Stage 2: GFR = 60-89
Stage 3A: GFR = 34-59
Stage 3B: GFR = 30-44
Stage 4: GFR = 15-29 (Begin planning for Kidney Replacement Therapy- In Center Hemodialysis(ICHD) or Home Hemodialysis (HHD))
Stage 5: GFR <15
What is GFR
Glomerular Filtration Rate (mL/min)
Estimates how much blood passes through the glomeruli
Why is it important to know what caused your patient’s CKD?
So the nurse and PCT can inquire about possible problems during data collection and assessment
What are signs & symptoms of fluid imbalance?
Hypertension
Edema
Shortness of breath
Why is sodium balance important?
Leads to volume expansion, increased cardiac output, increased peripheral vascular resistance, and increased blood pressure
What would you advise for a patient who complains of this CKD symptom:
Dry, Itchy Skin
Use hyper-fatted soaps and lotion