Module 1 Flashcards

1
Q

What are the Three Tenets of the cell theory?

A
  1. All living organisms are composed of one or more cells
  2. The cell is the basic unit of structure and organization in organisms.
  3. All cells come from pre-existing cells.
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2
Q

What does the cell theory describe

A

the properties of cells

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3
Q

Describe the two basic types of cells

A
  1. Prokaryotic-simple
    -no nucleus or any membrane bound organelles
    -smaller cells (~1-5 meu m)
    -always unicellular
    -binary fission
    -always asexual
    ex. Bacteria like E-coli
  2. Eukaryotes-more complex
    -has nucleus and membrane bound organelles
    -larger cells (~10-30 meu m)
    -usually multicellular
    -mitosis/meosis
    -sexual or asexual
    ex. plants and animals
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4
Q

List the 8 primary cells on the human body

A
  1. Epithelial Cells- form protective barrier in tissues and may specialize to absorb or secrete specific compounds
  2. Muscle cell- responsible for movement of the skeleton, heart, and many internal organs like stomach.
    They have specialized structures and proteins that allow them to generate motion.
  3. Nerve Cells- conduct electrical signals throughout the body, control the contraction of muscles, and are responsible for senses including taste, touch, smell, sight, and hearing
  4. Connective Tissue Cells- create extracellular material that holds cells together in tissue. They may be specialized to absorb or resist external forces (ex. tendons).
  5. Bone Cells- Form bones of the skeletal system that gives strength and supports the body. Include osteoclast cells that degrade bone and osteoblast cells that create new bone.
  6. Secretory cells- form glands and secrete substances (ex. mucous, hormones).
  7. Adipose Cells- located throughout body and store fat in the form of triglycerides which released when body is in a period of fasting.
  8. Red Blood cells- formed primarily in bone marrow and released into circulation where they move and deliver oxygen throughout body.
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5
Q

Are stem cells considered eukaryotic or prokaryotic?

A

Eukaryotic as can differentiate into many more cell types called blasts.
ex. red blood cells

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6
Q

Eukaryotic cells have many smaller structures contained within them called blank

A

organelles

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7
Q

What are the cellular structures to maintain life sustaining functions?

A

-Cytoskeleton
steel grindles holding buildings together
actin, microtubules and intermediate filaments are structural filaments that use mechanical resistance to stabilize membrane deformations.
myosin, kinesin, and dynein are motor (force) proteins that generate forces or motion

-Endoplasmic Recticulum (ER)
Acts as a highway system carrying molecules around cell and as a factory warehouse that makes lipids and proteins plus stores ions

-Endosomes, Lysosomes and Peroxisomes
peroxisomes deal with hazardous materials and “neutralize” it
endosomes are waste collectors who sort and breakdown contents which arrive outside cell and send through endocytosis to find spot
lysosomes recycle plants which breaks down proteins, lipids, and nucleic acids to molecular building blocks.
actin, microtubules and intermediate filaments are structural filaments that use mechanical resistance to stabilize membrane deformations.
myosin, kinesin, and dynein are motor (force) proteins that generate forces or motion

-Golgi apparatus
post office that processes and packages proteins then sends them across the cell.

-Mitochondria
power plant which produces energy for the cell to use in all of its processes in the form of ATP, a kind of cellular “currency”. number of mitochondria depends on function.

-Nucelus
leader of cell and makes “laws”. stores DNA and protects with a double membrane, nuclear pores, and a unique fluid called nucleoplasm

-Plasma Membrane
semi-permeable phospholipid bilayer which keeps cell organelles contained and regulates what can come in or out of cell through using specialized proteins.

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8
Q

What are the two fundamental building blocks to the cell?

A

water and carbon

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9
Q

What is one of the main formation causes of membrane

A

like disolve like-Hydrophobic attracting hydrophobic

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10
Q

3 key aspects to carbon molecules

A

-large
-non polar
so hydrophobic

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11
Q

define hydrophilic

A

molecules attracted to water

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12
Q

define hydrophilic

A

molecules then try to keep away from water

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13
Q

2 Most important properties of water

A
  1. Polarity- facilitates delivery of nutrients and removal of waste. allows cell to exist by facilitating movement of chemical messengers and makes excellent solvent
  2. Specific heat capacity
    high specific heat capacity allows for thermoregulation and acts as heat sink for many chemical reactions exchange heat between liquid and air
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14
Q

What is the importance of carbon

A

-building block to life
-small and can form up to four covalent bonds
-flexibility in bond numbers allows for large variety of molecules important to lipid life
ex. benzene (6 carbon and double bond), pyridine (double bond, w replacing a c), cyclopentane (single bond), cyclohexane (single bond)

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15
Q

Lipids

A

-lipids are building blocks for oils and fats
-made of hydrocarbon chains
-amphipathic but usually quiet hydrophobic
ex. cholesterols which regulate fluidity biological component to hormone etc.
Phospholipids which have a hydrophilic head hydrophobic tails, form bilayer
-trigylcerides which body fat in animals that stores energy

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16
Q

Carbohydrates

A

aka hydrated carbon
can be built into complex structures like starches
different classes
-Monosaccharides, single carbon molecule containing carbon, hydrogen and oxygen ex. glucose (sugar)
-Disacchardies, 2 monosaccharides connected by glycosidic bond ex. sucrose (table sugar) as glucose connected to fructose
-Oligosaccharides, 3 to 10 monosaccharides ex. raffinose
-Polyaccharides, longer chains, more complex, play many important cell roles ex. glycogen

17
Q

Nucelotides

A

-building blocks for nucleic acids like DNA and RNA
-form ATP
-make up chromosomes
-1 end unbounded hydroxil group from phosphate group and other end deoxyribosome sugar hydroxil group (OH)
3 components (bonded from condensation rxn and water break off when form like in proteins)
-Five carbon sugar
contains central 5 carbon sugar or monosaccharide
5’ end of sugar where phosphate group attached in single nucelotide
3’ end where phosphate group of different nucleotide on bond
-phosphate group
hydrophilic
attach to 5’ end carbon of one sugar and 3’ carbon of another by phosphodiester bond (covalent)
-part of DNA sugar-phosphate backbone
nucelotides have 1-3 phsophates attached 5’ why ATP can be used for energy as high energy bonds
-Nitrogen bases
attached to 1’ carbon of sugar in single nucelotide
Purines-> 2 rings/bonds in structure. Adenine and Guanine
Pyrimidines-> 1 ring structure Cytosine and thymine (DNA), uracil (RNA)
-hydrogen bonds between complementary bases on each strand which form a cross-linkage in DNA
-bases code for entire genetic material

18
Q

Amino Acids

A

building blocks of peptide and proteins
grouped into categories based on R -group
3- structural parts
-carboxylic acid group- excist as -COO- or pos (oh right side of c)
-amino group-exist as pos charge -NH3+ group too (h left side of c)
-R-group- unique to each amino acid, gives distinct molecular characteristic (r below c)

19
Q

Who solved DNA structure?

A

James Watson and Francis Crick solved structure DNA using image of DNA from Rosalind Franklin and Raymond Golsing
-wanted to form linked bonds

20
Q

Hydrophobic Amino Acids

A

GLaciers in ALAska VALIantly Locate ISOlated PROwlers Mhm (think ironic as non polar but alaska near poll)
TRY PHEw
-non polar
-in core of protein or attracting with other hydrophobic molecules like fats and lipids
ALPHATIC: (R group carbon chain straight)
glycine (Gly) (G)
Alanine (Ala) (A)
Valine (Val) (V)
Leucine (Leu) (L)
Isoleucine (lle) (l)
Proline (Pro) (P)
Methionine (Met) (M)
AROMATIC: (r group ring with double bond)
Trypothan (Trp) (W)
Phenylalanine (Phe) (F)

21
Q

Charged hydriohilic amino acids

A

LYucy’s ARt HISsed ( think ironic hissing from cats yet cats scared of water)
AShton GLowup
polar
pos or neg charge
outside of protein so can interact with water
POSITIVE
lysine (Lys) (K)
Arginine (Arg) (R)
Histidine (His) (H)
NEGATIVE
Aspartic acid (Asp) (D)
Glutamic acid (Glu) (E)

Hi

22
Q

Polar amino acids

A

TRY THe SERvent (OH group)
CYster GLUot ASs
hydrophilic
form hydrogen bonds which stable proteins
more common outside protein
OH GROUP
Tryosine (Try) (Y)
Threonine (Thr) (T)
Serine (Ser) (S)
NONE OH GROUP
Cysteine (Cys) (C) *(has sulfur-containing thiol (organic group) that can form covalent bonds called disulfide bond with another cysteine which maintains a 3D structure)
Glutamine (Gln) (Q)
Asparagine (Asn) (N)

23
Q

Aromatic Amino Acids

A

TRY
PHEn TRiPed
ring structures with double bonds
larger amino acids so gain or lose of these amino acids cause deformities
HYDROPHOBIC
Phenylalanine (Phe) (F)
Tryptophan (Trp) (W)
HYDROPHILIC
Tyrosine (Try) (Y)

24
Q

Amino acids connected by peptide bonds form what

A

peptides
ex. insulin the peptide hormone

25
Q

Proteins

A

-thousand of different types
-made of long chains of amino acids (typically over 20)
-polypeptides fold into 3D structure
ex. enzymes, receptors, structural proteins like keratin (make up nails and hair), hemoglobin (carries oxygen around the cell)
depeptide - looks like letters with nice straight bonds off
3D structure- looks like tangled necklace