modulation of movement by the cerebellum Flashcards

1
Q

cerebellum is also called what

A

little brain

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2
Q

what is the primary function of the cerebellum

A

detect the difference, or “motor error,” between an intended movement and the actual movement to reduce the error (i.e., if there is a discrepancy, the cerebellum can modify motor signals to correct any errors).

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3
Q

when can the motor error corrections be done

A

These corrections can be made both during the course of the movement and as a form of motor learning when the correction is stored

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4
Q

how does the cerebellum influence mvts and balance primarily

A

by modifying the activity patterns of the upper and lower motor neurons.

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5
Q

what does the cerebral hemispheres divide into

A

Left and Right ant and post lobes

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6
Q

what is the deep cerebellar nuclei and what 3 nuclei does it divide into

A

Clusters of cells in nuclei buried deep in the white matter of the cerebellum:
-Fastigial nucleus
-Interposed nuclei
-Dentate nucleus

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7
Q

what are the three cerebellar peduncles

A

sup, middle and inferior

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8
Q

cerebellar hemispheres can be divided into 3 parts

A

cerebrocerebellum, spinocerebellum, vestibulocerebellum

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9
Q

describe the cerebrocerebellum (position, receives input from where, function)

A

-Most lateral part of cerebellar hemisphere.
-Receives indirect input from many areas of the cerebral cortex.
-Planning, coordination and execution of complex spatial and temporal sequences of movement.
-Cognitive functions (e.g., timing, attention, sensation monitoring, motor learning)

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10
Q

describe the spinocerebellum (position, receives input from where, function of both parts)

A

-median zone
-Receives direct input from the spinal cord (proprioceptive information).
-Monitoring of ongoing movements (i.e., position of the body in space).
-Vermis is involved with (movement of the proximal m. or trunk muscles, movement of eyes)
-Paramedian zone is involved with (movement of distal muscles like arm & leg muscles)

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11
Q

describe the vestibulocerebellum (what lobes does it include, where does it receive its input, involved in reg of what)

A

-caudal-inf lobe of the cerebellum and included nodulus and flocculus
-receives input from vestibular nuclei in the brainstem
-involved in ref of mvt that maintain posture, balance and equilibrium

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12
Q

The connections between the cerebellum and other parts of the nervous system are made by what

A

3 large pathways called cerebellar peduncles

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13
Q

the cerebellar peduncles keep the cerebellum attached to what

A

brainstem

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14
Q

are the peduncles efferent, afferent or both

A

sup: mainly efferent (output)
middle: afferent pathways (input)
inf: multiple pathways (afferent and efferent)

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15
Q

describe the cortiopontocerebellar pathway

A

-Transmits information from motor, premotor cortex, somatosensory
cortex via the pontine nuclei.
-The pathway enters the cerebellum through the middle cerebellar
peduncle. Fibers decussate (i.e., cross to the other side).
-Projects mostly to the lateral areas: Cerebrocerebellum

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16
Q

cerebellar cortex neurons project to where

A

deep cerebellar nuclei (dendate and interposed)

17
Q

what pathway allows the cerebellum to influence posture and equilibrium (adjusting VCR, VSR, VOR reflexes)

A

cerebellar-vestibular pathway

18
Q

The cerebellar-vestibular-cerebellar pathways play a critical role in integrating and modulating vestibular signals to:

A

-Enable adaptive changes to the VCR,
-Distinguish head tilts from
translational movements,
-Distinguish passive movements of the head and body from those that are self-generated

19
Q

what segment of the brain is the most neuron dense

A

cerebellum/

20
Q

what cell is the main one in the cerebellum

A

purkinje cell

21
Q

Purkinje cells in the cerebellar cortex receive sensory information from the____ _____ and ____ nuclei through the _____ fibers and _____ fibers (excitatory inputs)

A

inf olive
pontine
mossy
climbing

22
Q

the cerebellar neurons output to the motor cortex generates what that can modify movements.

A

an error correction signal

23
Q

Activity of Purkinje cell and deep cerebellar nuclei cell at rest of the wrist.

A

At resting state: Both Purkinje cell and deep cerebellar nuclei cell are tonically active.

24
Q

Activity of Purkinje cell and deep cerebellar nuclei cell during movement of the wrist.

A

During movement of the wrist (i.e., rapid alternating movements) both cell types receive a transient inhibition that blocks their tonic activity.

25
Q

what are the higher functions of the cerebellum

A

-Sensory acquisition,
-Motor attention,
-Timing of motor actions,
-Prediction and preparation of movement,
-Motor sequence learning and memory.

26
Q

what is the helper structure

A

cerebellum

27
Q

cerebellum circuitry could be acting as a ______ and _____ the body movement accordingly. It helps to coordinate motor actions _____

A

predictor (predicts surrounding movements)
adjusts
unconsciously

28
Q

how does the cerebellum help in motor coordination

A

by parallel computations (participates in the integration of motor function)

29
Q

what is the cerebellum’s role in motor cognition

A

learning motor sequences,
memory of motor actions

30
Q

what is the cerebellum’s role in non-motor functions

A

e.g, the organization and coordination of thought and emotion