Moderate EF

Question 1

Who were the the main authors?

Answer 1

Alaswad and O’Neill

Question 2

How many patients in the study?

Answer 2

891

Question 3

How many had an LVEF < or equal to 35%?

Answer 3

661

Question 4

How many had an LVEF > 35%?

Answer 4

230

Question 5

Describe the patients that had an EF > 35%?

Answer 5

Older, more extensive coronary artery disease with more diseased vessels, more multivessel intervention and used rotational atherectomy. They also had a higher prevalence of high risk clinical features such as renal failure and diabetes mellitus. More congestive heart failure, previous MI, previous PCI, previous CABG,

Question 6

Despite having LVEF >35%, this selected group had what?

Answer 6

Severe co-morbidites and complex angiographic features.

Question 7

Where did the data come from for this study?

Answer 7

Global cVAD registry

Question 8

What is the cVAD registry?

Answer 8

Multicenter registery

Question 9

What was the average STS score for predicted mortality and morbidity in the moderate EF group?

Answer 9

4.87 / 25.5 respectively.

Question 10

Patients with non-severely depressed LVEF who underwent HRPCI with MCS had a higher degree of ____

Answer 10

CAD compared with the severely reduced LVEF.

Question 11

The overal event rates in these patients are relatively low compared to what?

Answer 11

Their predicated surgical mortality

Question 12

Numerous clinical features have associated with poor outcomes in PCI.

Answer 12

Advanced Age
High prevalance of renal failure
Diabetes Mellitus
Previous MI
Previous Revasc
High STS predicted mortality and morbidity.
LM involvement and Ostia, proximal and severely calcified lesions

Question 13

Those patients treated with IABP had a greater decrease in MAP with each subsequent _____ treated

Answer 13

Vessel

Question 14

The analysis demonstrated that many patients were transferred from other hospitals suggesting what?

Answer 14

That they needed HRPCI in a tertiary or quaternary center or at least escalation of care.

Question 15

One may hypothesize that HRPCI supported with MCS may have allowed complex PCI affirming the choice of the operator to use MCS during intervention. Interestingly, the actual mortality for patients who underwent Impella support PCI with non-depressed LVEF was _____, which was lower than their STS predicted mortality.

Answer 15

1.67%

Question 16

There’s been a noticeable increase in patients age and co-morbidities, physicians are currently treated more complex multivessle CAD and therefore what?

Answer 16

There is a need for MCS during HRPCI to ensure patient safety and optimize procedural outcomes

Question 17

_____% of patients who underwent HRPCI had non-severely depressed LVEF

Answer 17

25%