MOD4

Question 1

4 features of signal transduction

Question 1

2 types of receptors

Question 2

2 major typs of cellular responses

Question 3

arrow meaning (activation, inactivation, inhibitor)

Question 4

4 ways to turn signals on/off

Question 5

5 molecular switches

Question 6

phosphorylation

Question 7

phosphorylation vs GTP-binding proteins

Question 8

degradation by proteasome

Question 9

pathway 1: GPCR

Question 10

b-adrenegric pathway

Question 11

examples of kinase turn on/off

Question 12

effect of cAMP on PKA

Question 13

CREB + CRE

Question 14

how is the PGCR pathway turned OFF

Question 15

where is GTP hydrolysed in GPCR pathway

Question 16

desensitisation of B-adrenergic receptors

Question 17

pathway 2: RTK

Question 18

phosphorylation of TRK

Question 19

GTPASE on/off

Question 20

GTPase RAS

Question 21

MAPK pathway

Question 22

MAPkkk-MAPkk-MAPk cascade

Question 23

what if ras constitutively ON

Question 24

4 ways to terminate P2:RTK

Question 25

cytokine receptors

Question 26

pathway 3: cytokine receptor

Question 27

P3-Jak-STAT

Question 28

termination of JAK-STAT

Question 29

pathway 4: TNF-a

Question 30

NF-Kb

Question 31

western blot (refer to image)

Question 32

EGF pathway

Question 33

co-immunoprecipitation