Mod3: MINIMALLY INVASIVE CARDIAC PROCEDURES Flashcards

1
Q

MINIMALLY INVASIVE CARDIAC PROCEDURES

Minimally invasive cardiac procedures are becoming more and more of a mainstay. They are replacing the traditional sternotomy for which pt population?

A

Pts that are not candidate for open sternotomy

While minimally invasive cardiac procedures haven’t been fully adopted for use in all pt’s populations, they are becoming more and more favorable

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2
Q

OFF PUMP CABG

Coronary Artery Bypass Grafting (CABG) has traditional been performed with the use of which machine?

A

The Cardio Pulmonary Bypass (CPB) machine

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3
Q

OFF PUMP CABG

Studies have suggested that the heart function is better preserved if it is managed which way during the operation?

A

If it is not stopped during the operation

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4
Q

OFF PUMP CABG

Which approach to cardiac surgery is also known as the “beating heart” surgery or OBCAB

A

OFF PUMP CABG

Technique developed as new revolutionary procedure performed without the use of a cardiopulmonary bypass machine

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5
Q

OFF PUMP CABG

Advantages:

A

Reduction in risk of stroke,

<em>Although the rate of neuro cognitive dysfunction remains the same</em>

Less systemic anticoagulation needed

Thought to avoid potential morbidities associated with extracorporeal membrane

Faster recovery and reduced procedural costs

Eliminate risk of aortic manipulation for cannulation and cross-clamping

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6
Q

OFF PUMP CABG

Potential morbidities associated with extracorporeal membrane that may be avoided by performing “Off Pump CABG” inlude?

A

Systemic inflammatory response

Platelet activation

Fibrinolysis

Bleeding

Vasodilatory shock

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7
Q

OFF-PUMP CABG MORBIDITY AND MORTALITY

What are disadvantages of “Off-pump CABG”?

A

More challenging, requiring additional training

Difficulty performing distal anastomoses on the distal part of the beating heart

Motion of coronary artery hampers accurate anastomotic suturing

<em>The beating heart causes the coronaries to move, which can impede accurate anastomotic suturing</em>

Heart must be manipulated and lifted to reach posterior and lateral targets

<em>And this can cause a significant left to right ventricular hemodynamic deterioration</em>

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8
Q

OFF-PUMP CABG MORBIDITY AND MORTALITY

How does “Off-pump CABG” affect morbidity and mortality at 1 and 3 year marks

A

At 1 and 3 year marks, OPCAB showed a reduction in morbidity and mortality

Initially, studies that evaluated mortality showed a reduction in death a/w off pump CABGs

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9
Q

OFF-PUMP CABG MORBIDITY AND MORTALITY

Why are higher long term mortality rates (at the At 5 year mark) seen with “Off-pump CABG”?

A

Reduction in graft patency (Worse graft patency)

Increased risk for repeat revascularization (Less complete revascularization)

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10
Q

OFF-PUMP CABG MORBIDITY AND MORTALITY

What does “Repeat revascularization” means?

A

….

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11
Q

OPCAB PATIENT SELECTION

What’s the goal for “Off-pump CABG”?

A

Complete revascularization

Pts are selected with this goal in mind

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12
Q

OPCAB PATIENT SELECTION​

T/F: OPCAB has been choosen for low-risk as well as high-risk pts

A

True

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13
Q

OPCAB PATIENT SELECTION​

What’s an example of a low risk pt for whom OP-CABG can be choosen?

A

Pt with a single of fewer number of diseased vessels

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14
Q

OPCAB PATIENT SELECTION​

What’s are examples of a high-risk pt for whom OP-CABG can be choosen?

A

Patients with contraindications to conventional CABG

Pts who have plaque in the ascending aorta

Pts with extensive aortic atheromatous or calcific changes

Pts who have comorbidities such as stroke, liver cirrhosis and renal or pulmonary dysfunction

History of stroke

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15
Q

OPCAB PATIENT SELECTION​

Why is OP-CABG indicated for pts who have plaque in the ascending aorta, or pts who show extensive aortic atheromatous or calcific changes?

A

Because conventional CABG precludes them from aortic cross-clamping

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16
Q

OPCAB PATIENT SELECTION

Besides low and high risk groups, for which other categories of pts is OP-CABG indicated?

A

Patients with isolated proximal LAD CAD/fewer number of diseased vessels

Occasionally patients with LAD and proximal RCA CAD

Pts with No prior cardiac surgery history

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17
Q

OPCAB PATIENT SELECTION

Other considerations for OP-CABG include?

A

Surgeon expertise

Extent of atherosclerosis of ascending aorta

Extent of technically challenging anatomy

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18
Q

MINIMALLY INVASIVE DIRECT CORONARY ARTERY BYPASS

What’s the most popular alternative to sternotomy that utilizes a limited thoracotomy incision?

A

Minimally invasive Direct Coronary Artery Bypass

Also known as a MIDCAB

MIDCAB is a minimally invasive approach to conventional CABG​

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19
Q

MINIMALLY INVASIVE DIRECT CORONARY ARTERY BYPASS

MIDCAB can be performed two ways

A

Can be performed with

Elimination of CBP and cardioplegia, or

Elimination of cardioplegia only

For the purpose of this lecture, we will focus on the option that involves Elimination of CBP and cardioplegia

So the MICAB will be very similar to “off-pump CABG”

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20
Q

MINIMALLY INVASIVE DIRECT CORONARY ARTERY BYPASS

Why is the A left anterior thoracotomy is used for the MIDCAB procedure?

A

It allows for direct access to the IMA for harvesting and grafting to the LAD

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21
Q

MINIMALLY INVASIVE DIRECT CORONARY ARTERY BYPASS

The MIDCABs can be categorized into three groups; that are?

A

Direct access MIDCAB

Thoracoscopic MIDCAB

Robotic MIDCAB

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22
Q

MINIMALLY INVASIVE DIRECT CORONARY ARTERY BYPASS

Why are Thoracoscopic MIDCABs and Robotic MIDCAB also known as endoscopic MIDCABs?

A

Because they use a video-assisted device

Many facilities that perform MIDCABs use the Thoracoscopic or Robotic approaches

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23
Q

MINIMALLY INVASIVE DIRECT CORONARY ARTERY BYPASS

The standard approach MIDCAB that uses an anterior thoracotomy is also known as

A

Direct access MIDCAB

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24
Q

MINIMALLY INVASIVE DIRECT CORONARY ARTERY BYPASS

Why are many Centers shying away from Direct access MIDCAB?

A

Visualization of the LIMA is difficult and

The rib-spreading required for visualization is associated with postoperative thoracotomy pain

<em>Many facilities that perform MIDCABs use the Thoracoscopic or Robotic approaches</em>

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25
Q

MINIMALLY INVASIVE DIRECT CORONARY ARTERY BYPASS​

Which MIDCAB approach uses small thoracoscopic ports for incision sites

A

Thoracoscopic MIDCAB

It uses the Non-rib-spreading technique

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26
Q

MINIMALLY INVASIVE DIRECT CORONARY ARTERY BYPASS​

What are benefits of the Non-rib-spreading technique used in Thoracoscopic MIDCABs?

A

Non-rib-spreading technique is associated with

Very good flow down the LIMA, and

High LIMA-LAD graft patency

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27
Q

MINIMALLY INVASIVE DIRECT CORONARY ARTERY BYPASS​

Which MIDCAB approach uses thoracoscopic ports, but also utilizes a robot to harvest the LIMA

A

Robotic MIDCAB

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28
Q

MINIMALLY INVASIVE DIRECT CORONARY ARTERY BYPASS​

What are benefits of Robotic MIDCAB

A

Excellent visualization and maneuverability of instruments inside the thoracic cavity

Good quality of harvested LIMA

Good LIMA to LAD anastamosis

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29
Q

MINIMALLY INVASIVE DIRECT CORONARY ARTERY BYPASS​

Which MICAB approach requires deflation of the lung on the operative side?

A

Robotic MIDCAB

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30
Q

MIDCAB ADVANTAGES

What are advantges of MIDCAB’s small thoracic incisions, especially the non-rib-spreading ones

A

Eliminate the potential morbidity a/w CABG and the median sternotomy

Results in potential for more rapid and complete recovery

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31
Q

MIDCAB ADVANTAGES

For which cardiovascular procedures do utilizing MIDCABs offers advantages?

A

Repair congenital defects like ASDs and VSDs

Aortic valve replacements

MV repairs

Multivalves procedures

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32
Q

MIDCAB ADVANTAGES

Overall, what are advantages of MIDCAB procedures?

A

Lower Infection rate

Less Cost (25% less than conventional CABG surgery)

Shorter length of stay

Faster Recovery (reduced risk of complications; can return to normal activity within 2 weeks)

Less Bleeding and Blood trauma (the damage to the blood from the CPB machine is avoided; smaller incision-less blood loss)

Available to more patients (poor candidates for conventional CPB may be candidates for less invasive techniques)

Applicable to a broad range of complex cardiac procedures

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33
Q

PLACEMENT OF INCISION DURING MINIMALLY INVASIVE HEART VALVE SURGERY

Where is the incision placed for minimally invasive aortic valve surgery?

A

Below the right clavicle, and

Above the right nipple

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34
Q

PLACEMENT OF INCISION DURING MINIMALLY INVASIVE HEART VALVE SURGERY

Where is the incision placed for minimally invasive mitral and intracupsid valve surgery?

A

Below the right nipple

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35
Q

MIDCAB DISADVANTAGES

What percent reduction in mortality rates was oberved when MIDCABs were performed by more experienced surgeons?

A

5% reduction in mortality rates

A meta-analysis documented a significant surgeon volume relationship with a 5% reduction in mortality rates in surgeons who perform high volumes of these procedures

MIDCABs Require experienced surgeon for best outcomes

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36
Q

MIDCAB DISADVANTAGES

What’s a disadvantage of the small MIDCAB incisions?

A

Limited access to specific regions of the heart

Poor access to distal RCA and PDA

Make complete re vascularization difficult, especially when it comes to identifying and bypassing smaller myocardial vessels

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37
Q

MIDCAB DISADVANTAGES

Why is constructing inflows to secondary grafts with MIDCABs procedures?

A

Proximal anastomosis to the ascending aorta more challenging

38
Q

MIDCAB DISADVANTAGES

What would will make Robotic surgery procedures technically difficult?

A

Any anatomical issues that hinder port placement or limit robotic arm movement

Prior thoracic surgery

Chest radiation

Thoracic trauma

39
Q

MIDCAB DISADVANTAGES

T/F: Higher blood transfusion rates associated with robotic cardiac surgery than with other robotic procedures

A

True

40
Q

MIDCAB PATIENT SELECTION

Why is appropriate patient selection is important?

A

To reduce the risk of perioperative complications

41
Q

MIDCAB PATIENT SELECTION

Robotic or Thoracoscopic (Endoscopic) approaches may not suitable for smaller pts; why?

A

Insufficient intrathoracic space for CO2 insufflation

42
Q

MIDCAB PATIENT SELECTION

T/F: Except for difficulty with smaller pts and endoscopic procedures, the pt selection for MIDCAB is Similar to the patient selection for Off pump CABG

A

True

43
Q

MIDCAB PATIENT SELECTION

Except for difficulty with smaller pts and endoscopic procedures, the pt selection for MIDCAB is Similar to the patient selection for Off pump CABG and include?

A

Patients who are considered low risk with anterior lesions specifically of the LAD

Those with fewer number of diseased vessels

High risk patients or patients with contraindications for bypass surgery

Or if they are scheduled to have a sternotomy for another cardiac procedure

44
Q

MIDCAB PATIENT SELECTION

High risk patients or patients with contraindications for bypass surgery include

A

Extensive ascending aorta atheromatous or calcific changes

Patients who require reoperation, but in whom a sternotomy or CPB is contraindicated/higher risk

Future sternotomy for other cardiac procedure

45
Q

MIDCAB PATIENT SELECTION

Patients who require reoperation, but in whom a sternotomy or CPB is contraindicated/higher risk include:

A

Patients who require redo-sternotomy, but have cardiac sutures adhering to the posterior sternum

Previous sternal infection

Mediastinal radiation

46
Q

OPCAB and MIDCAB SURGICAL CONSIDERATIONS

Describe vessel harvesting, incision and anastamosis with the MIDCAB procedure (Anterior thoracotomy approach)

A

an anterior thoracotomy is made and

the internal mammary artery (Left or Right) is harvested from the thoracic wall

For anastamosis to the LAD

47
Q

OPCAB and MIDCAB SURGICAL CONSIDERATIONS

Describe vessel harvesting, incision and anastamosis with the OPCAB procedure

A

The conduit vessels, either the saphenous vein, or radial arteries, are harvested in the same fashion that they would be for a traditional CABG

A sternal incision is then made

The pericardium is opened and tacked to the edges of the mediastinum

<em>This raises the heart out of the chest wall</em>

Sternal retractors placed

<em>Allow for the placement of surface pressure devices on the myocardium called stabilizers</em>

48
Q

OPCAB and MIDCAB SURGICAL CONSIDERATIONS

What results when the pericardium is opened and tacked to the edges of the mediastinum?

A

This raises the heart out of the chest wall

49
Q

OPCAB and MIDCAB SURGICAL CONSIDERATIONS

For OP-CAB what’s another name for the surface pressure devices on that are placed on the myocardium after Sternal retractors are placed?

A

Stabilizers

50
Q

OPCAB and MIDCAB SURGICAL CONSIDERATIONS

Where are Stabilizers placed? What’s their function?

A

Placed on epicardium over planned site of arteriotomy

Stabilize the myocardium to reduce movement of the site of anastamosis

Example of stabilizer: Octopus Stabilizer

51
Q

OPCAB and MIDCAB ANESTHETIC CONSIDERATIONS

For both OPCAB and MIDCAB, why must the cardiopulmonary bypass machine is on standby?

A

In the event that emergency bypass is needed

A perfusionist must be in attendance

52
Q

OPCAB and MIDCAB ANESTHETIC CONSIDERATIONS

T/F: Double lumen tube, bronchial blocker, or endobronchial tube will be inserted for MIDCAB procedures

A

True

Why?…

53
Q

OPCAB and MIDCAB ANESTHETIC CONSIDERATIONS

Why should External defibrillator pads should be placed for both procedures; especially for MIDCAB procedures?

A

Because the surgeon will not have direct access to the heart to place internal pads in the event of V-fib

54
Q

OPCAB and MIDCAB ANESTHETIC CONSIDERATIONS

What monitors must be available for both OP-CAB and MIDCAB procedures?

A

All the traditional monitors for traditional cardiac surgery:

5-lead EKG - Pulse oximetry

Temperature monitoring - Radial arterial line

Central venous catheter/ PAC ?

Foley Catheter - TEE

55
Q

OPCAB and MIDCAB ANESTHETIC CONSIDERATIONS

What are the anesthetic goal for off pump cases?

A

Ensure that there is maximum cardiac protection

Stable hemodynamics and cardiac rhythm

Promote fast-track anesthesia

56
Q

OPCAB and MIDCAB ANESTHETIC CONSIDERATIONS​

What does fast-track anesthesia means? What’s required to achieve it?

A

Extubation within 0-6 hours after ICU admission

Adequate postoperative analgesia is required to achieve fast-track anesthesia

57
Q

OPCAB and MIDCAB ANESTHETIC CONSIDERATIONS

How can anesthesia be delivered for OPCAB and MIDCAB?

A

General anesthesia (GA) with opioids and inhalational agents or TIVA

Combined GA with controlled ventilation and neuroaxial blockade using high thoracic epidural

58
Q

OPCAB and MIDCAB ANESTHETIC CONSIDERATIONS

General anesthesia with the use of opioids and inhalational agents offer the advantage of

A

Anesthetic ischemic preconditioning

59
Q

OPCAB and MIDCAB ANESTHETIC CONSIDERATIONS

Why must careful consideration be taken with the use of neuromuscular blocking agents during General anesthesia

A

May interfere with the goal is fast-tracking

Roc and Nimbex are recommended

60
Q

OPCAB and MIDCAB ANESTHETIC CONSIDERATIONS

Remifentanil a good option for General anesthesia (GA) with opioids and inhalational agents or TIVA, but

A

must ensure adequate analgesia prior to discontinuation

61
Q

OPCAB and MIDCAB ANESTHETIC CONSIDERATIONS

What are the benefits of combined GA with controlled ventilation and neuroaxial blockade using high thoracic epidurals?

A

Improved analgesia, pulmonary outcomes, and reduction in M&M

They ensure hemodynamic stability and decrease myocardial O2 demands by attenuating the neuro hormonal response

62
Q

OPCAB and MIDCAB ANESTHETIC CONSIDERATIONS

When must thoracic epidural be inserted to reduce the risk of developing epidural hematomas?

A

The day before surgery or

1 hour prior to Heparin administration (minimally)

Important to assess patient’s preoperative anticoagulation status

63
Q

OP-CAB HEMODYNAMIC CONSIDERATIONS

Hemodynamic instability during off pump cabgs due to

A

Myocardial ischemia

Mobilization and stabilization of heart for OPCAB

Pushing and tilting the heart for exposure of anastomosis sites

64
Q

OP-CAB HEMODYNAMIC CONSIDERATIONS

Mobilization and stabilization of heart for OPCAB necessitates pushing and tilting the heart for exposure of anastomosis sites. What are the negative consequences of this?

A

Reduces stroke volume and ABP

Increases CVP and RVEDP

which leads to decreased RVOT flow

Distortion of mitral and tricuspid annuli

which can either cause or worsen regurgitation through those valves

65
Q

OP-CAB HEMODYNAMIC CONSIDERATIONS

Mobilization and stabilization of heart for OPCAB necessitates pushing and tilting the heart for exposure of anastomosis sites. What’s the treatment for the negative effects associated with this?

A

Inotropes and vasopressors

Adequate, but cautious fluid management

Fluid loading prior to stabilizing device being placed

Trendelenburg

66
Q

OP-CAB HEMODYNAMIC CONSIDERATIONS

Mobilization and stabilization of heart for OPCAB necessitates pushing and tilting the heart for exposure of anastomosis sites. This is could have negative effects including hypotension. What should you do If hypotension persists despite the treatment?

A

Myocardial ischemia should be suspected and evaluated by monitoring the EKG and the TEE

Consider conversion to cardiopulmonary bypass if hypotension unresponsive

67
Q

OP-CAB HEMODYNAMIC CONSIDERATIONS

Mobilization and stabilization of heart for OPCAB necessitates pushing and tilting the heart for exposure of anastomosis sites. This could have negative effects that are typically not seen with MIDCAB. Why not?

A

Not much cardiac manipulation

68
Q

MIDCAB HEMODYNAMIC CONSIDERATIONS

Hemodynamic instability less likely - why?

A

Reserved for single vessel disease of the LAD

Procedure done on anterior side of the heart

Not much heart manipulation

69
Q

MIDCAB HEMODYNAMIC CONSIDERATIONS

Why is there a potential for ventilation/perfusion issues in endoscopic MIDCAB procedures that utilize a robot?

A

One lung ventilation required with double lumen ETT or bronchial blocker

May result in oxygen desaturations

70
Q

MIDCAB HEMODYNAMIC CONSIDERATIONS

Why do endoscopic MIDCAB procedures that utilize a robot result in oxygen desaturations from One-lung ventilation?

A

The non ventilated lung continues to be perfused despite it not taking part in gas exchange

Subsequently, these pts develop a “right to left intrapulmonary shunt”

Deoxygenated blood from non-inflated lung mixing with oxygenated blood from ventilated lung

Hypoxic Pulmonary Vasoconstriction (HPV) attempts to correct by reducing blood flow to non-ventilated lung

However we do know that HPV can be attenuated by anesthetic gasses a vasopressors

There is also a risk for barotrauma!!!

71
Q

MIDCAB HEMODYNAMIC CONSIDERATIONS

Which gas is used for insufflation of the thoracic cavity (left hemithorax)? Why?

A

CO2

This allows for exposure of the heart and great vessels as well as preventing smoke formation during cautery usage

72
Q

MIDCAB HEMODYNAMIC CONSIDERATIONS

Which CO2 levels are adequate to visualize cardiac structures?

A

5-10 mmHg

73
Q

MIDCAB HEMODYNAMIC CONSIDERATIONS

What’s a possible negative effect of CO2 levels of 5-10 mmHg

A

Increased intrathoracic pressure

Decreased venous return

Which can impair systemic BP and worsen hypoxia

74
Q

MIDCAB HEMODYNAMIC CONSIDERATIONS

Negative effects () of 5-10 mmHg of CO2 used to insufflation thoracic cavity will be more pronounced in patients with

A

Reduced ventricular function

Increased risk for hypercapnia

75
Q

MIDCAB HEMODYNAMIC CONSIDERATIONS

Patient positioning; why?

A

Supine position with roll underneath left scapula

  • Facilates surgical exposure*
  • Provides adequate room for the robot and the robotic arm to move freely*
76
Q

MIDCAB HEMODYNAMIC CONSIDERATIONS

Why is it important to note the position of the left arm?

A

The left arm must be positionned posteriorly at the pt side for adequate exposure

However, caution must also be used to watch for brachial plexus injuries

This becomes especially important in longer procedures where the pt is in this position for a long period of time

77
Q

OPCAB and MIDCAB ANESTHETIC CONSIDERATIONS

Which technique is used by many surgeons to create the anastomosis in a blood-less field?

A

Temporary occlusion of the target coronary artery

Surgeons will temporarily occlude the target coronary artery to create a blood-less field for anastomosis of the grafts

78
Q

OPCAB and MIDCAB ANESTHETIC CONSIDERATIONS

Heparin should be administered prior to the occlusion of the target coronary artery. At which dose and for ACT target?

A

150-200 units/kg, target ACT >300 s

79
Q

OPCAB and MIDCAB ANESTHETIC CONSIDERATIONS

During Temporary occlusion of the target coronary artery, maintain HR and MAP of:

A

HR 70-80 bpm, MAP >70 mmHg

This is to allow for adequate coronary perfusion

80
Q

OPCAB and MIDCAB ANESTHETIC CONSIDERATIONS

The patient’s response to occlusion depends on

A

Degree of collateral circulation

81
Q

OPCAB and MIDCAB ANESTHETIC CONSIDERATIONS

Why is Temporary occlusion of the target coronary artery tolerated poorly in Moderate stenosis?

A

Poor collateral circulation

The stenotic lesion has not been present for long enough to develop adequate collateral circulation

82
Q

OPCAB and MIDCAB ANESTHETIC CONSIDERATIONS

Why is Temporary occlusion of the target coronary artery tolerated better in severe stenosis?

A

More well developed collateral circulation

83
Q

OPCAB and MIDCAB ANESTHETIC CONSIDERATIONS

Prior to occlusion, the surgeon may temporarily occlude the coronary artery and then re-perfuses it prior to making the anastomosis. What is this technique called?

A

Ischemic preconditioning

The surgeon may do this a couple of times to preconditionne the heart to be able to tolerate longer period of ischemia that would be required to make the final anatamosis

84
Q

OPCAB and MIDCAB ANESTHETIC CONSIDERATIONS

What’s the purpose of Ischemic preconditioning?

A

To enhance myocardial performance to decrease ischemic damage during a subsequent prolonged period of ischemia

85
Q

OPCAB and MIDCAB ANESTHETIC CONSIDERATIONS

Which drugs can also be increased for preconditioning?

A

Inhalational agents

Use of inhalational agents => anesthetic preconditioning

86
Q

OPCAB and MIDCAB ANESTHETIC CONSIDERATIONS

When do ischemic changes that occur on the EKG tend to disappear?

A

After reperfusion

Ischemic changes disappear after coronary re-perfused

87
Q

OPCAB and MIDCAB ANESTHETIC CONSIDERATIONS

The ischemic changes that occur on the EKG tend to disappear after reperfusion. So why would the EKG sometimes show T-wave inversion, or the TEE may show regional wall abnormality?

A

This is Secondary to myocardial stunning and reperfusion injury

88
Q

OPCAB and MIDCAB ANESTHETIC CONSIDERATIONS

Which Eeectrolytes should be closely monitored postop? why?

A

Potassium or Magnesium

To prevent reperfusion arrythmias

89
Q

OPCAB and MIDCAB ANESTHETIC CONSIDERATIONS​

How should arrythmias be treated?

A

Arrythmias should be treated promptly

Use of a pacemaker should be employed if necessary

90
Q

OPCAB and MIDCAB ANESTHETIC CONSIDERATIONS

Neuromuscular blockade reversal will depend on

A

Stability of the patient and

How soon extubation is anticipated

91
Q

OPCAB and MIDCAB ANESTHETIC CONSIDERATIONS

What’s required for extubation to take place?

A

Hemodynamic stability and

Warm normovolemic patient who is alert and pain free

92
Q

OPCAB and MIDCAB ANESTHETIC CONSIDERATIONS

What’s the special consideration for using Protamine for heparin reversal?

A

Consider on a patient by patient basis

Full versus partial reversal