Mod-Severe TBI Flashcards
Prognosis
Highly variable
Depends on
- severity of injury
- age
- CT abnormalities
- concomitant injuries
- length of post-traumatic amnesia (PTA)
Post-traumatic amnesia (PTA)
Inability to create new memories
Mild: <24 hours
Mod: 1-7 days
Severe: >7 days
> 2 weeks, prognosis is less optimistic
Glasgow coma scale
Measures severity
3 categories
- verbal response
- eye opening
- motor response
Mild: 13-15
Moderate: 9-12
Severe: 3-8
See chart
Primary brain injuries
Concussion
Diffuse axonal injury
Anoxic/hypoxic brain injury
Contusion
Laceration
Hemorrhage
Secondary brain injuries
Hypotension
Hypoxia
Increased ICP
Cerebral edema
Vasospasm
Failure of autoregulation
Excitotoxicity
Production of free radicals
Diffuse brain injuries
Concussion
Diffuse axonal injury (DAI)
Anoxic/hypoxic brain injury
Metabolically active areas (hippocampus, purkinje cells, basal ganglia)
Focal brain injuries
Contusion
Laceration
Hemorrhage
Diffuse axonal injury (DAI)
Widespread stretching of axons caused by rotation of the brain
Involves white matter, deeper structures if more severe
Anoxic/hypoxic injury
Oxygenation status
MOI: asphyxiation, drowning, anaphylaxis
Parietal/occipital cortices, hippocampus, cerebellum, basal ganglia
Poor prognostic factors
Hypotension
Hypoxia
Apnea
Cyanosis
Increased intracranial pressure
Intracranial pressure
Increased volume in one area decreases volume in another
Increased pressure can cause midline shift of herniation
Management
- surgical decompression
- elevate HOB
- cooling
- diuretics
How to limit secondary injury
Decrease brain metabolism/energy needs
- paralytics decrease stimulation
- barbituates decrease metabolic rate
- hypothermia decreases metabolic rate
Possible consequences of TBI
Focal deficits based on area of injury
Cranial nerve damage
Cognitive and neurobehavioral issues
Occipital contusions
visual processing difficulties or cortical blindness
Motor cortex injury
contralateral paresis or paralysis
Brainstem injury
disruption in cardiac and respiratory function
Possible complications of TBI
heterotopic ossifications
Intracranial infection
Seizures
post ictal
period after seizure ends but before patient has returned to his or her baseline mental status
status epilepticus (SE)
A seizure that lasts longer than 5 minutes, or having more than 1 seizure within a 5 minutes period, without returning to a normal level of consciousness between episodes
Medical emergency, can be fatal
Potential causes of acute seizures
Metabolic
Drug induced
Illness
Neurologic
Epilepsy prognosis
Increased mortality
Increased risk of death by asphyxia
Increased risk of drowning
Increased risk of depression/suicide