Mod. 6 (ATI Ch. 18, 26, 14, 23, 10, 13, 22) Flashcards
Mood disorders neurotransmitters
- serotonin
- dopamine
- epinephrine
- GABA
Depressive disorders
recognized by DSM-5
(5)
- Major depressive disorder (MDD)
- seasonal affective disorder (SAD)
- Persistent depressive disorder (previously) known as dysrhythmic disorder)
- Premenstrual dysphoric disorder (PMDD)
- substance-induced depressive disorder
SIGECAPS
pneumonic for questions to ask regarding:
sleep interest guilt energy concentration appetite psychomotor suicidality
MDD phases Care
acute phase: severe findings of depression
- Tx generally 6 to 12 weeks in duration
- potential need for hospitalization
- reduction of depressive manifestations is the goal Tx***
- assess suicide risk and implement precautions
continuation phase: ^ ability to function
- Tx generally 4 to 9 months in duration
- relapse prevention through education, medication, therapy, and psychotherapy is goal***
maintenance phase: remission of manifestations
- phase can last for years
- prevention of future depressive episodes is goal***
DIGFAST mnemonic to guide questioning for a bipolar patient
distractibility indiscretion grandiosity or inflated self esteem flight of ideas or racing thoughts activity increase sleep deficit talkativeness or pressured speech
Only for clients who have stopped drinking
meds.
naltrexone
acamprosate (Campral)
disulfiram (Antabuse)
Milieu therapy for depression
suicide risk self-care communication maintenance of a safe environment counseling
Socialcultural Theories in substance use
Alaska natives and Native American may have high percentage of members who have alcohol disorder
Peer presssure
Older adult clients
Expected Findings in substance use and addictive disorders
What to ask
nurse should use open-ended questions to obtain following;
~ type of substance of addictive behavior
~ pattern and frequency of substance use
~ amount of substance used
~ age at onset of substance use
~ changes in occupational/ school performance
~ changes in use patterns
~ periods of abstinence in history
~ previous withdrawal manifestations
~ date of last substance use or addictive behavior
Review of systems in substance use/ addictive disorders
- blackout or loss of consciousness
- changes in bowel movements
- weight loss or weight gain
- experience of stressful situation
- sleep problems
- chronic pain
- concern over substance use
- cutting down on consumption or behavior
Population- Specific Considerations
Substance use and addictions
- rate of substance use is higher in age 18- 25
- Older adults: prone to falls, injuries, memory loss, somatic reports (headaches), changes in sleep patterns
» indications show decrease in ability for self-care (functional status), urinary incontinence, manifestations of dementia
» happens at lower doses
» consider many drug interactions (polypharmacy)
Standardized Screening Tools
for substance use/ addictive disorders
- Michigan Alcohol Screening Test (MAST)
- Drug Abuse Screening Test (DAST) or DAST-A: adolescent version
- CAGE Questionnaire: asks questions of clients to determine how they perceive their current alcohol use
- Alcohol Use Disorders Identification Test (AUDIT)
- Clinical Institute Withdrawal Assessment of Alcohol Scale, Revised (CIWA-Ar)
- Clinical Opiate Withdrawal Scale
Commonly Used Substances
substance use and addictive disorders
- Opioid Agonists
- CNS depressants
- CNS stimulants
- Other
Opioid Agonists
generalized CNS depression, listed as Schedule 2
Heroin, morphine, hydromorphone can be injected, smoked, inhaled, or swallowed.
- effects: rush of euphoria, relief from pain
- effects of intoxication: slurred speech, impaired memory, pupillary changes.
Decreased respirations and LOC which can cause death.
Maladaptive behavioral or psychological changes (impaired judgement)
***Antidote- naloxone IV
CNS depressants
physiological and psychological dependence
Alcohol: blood alcohol concentration of 0.08% is considered legally intoxicated for drivers. Death could occur for levels > 0.4%
- Effects of excess (major): respiratory arrest, peripheral collapse (low bp causes collapse of vessels), death (large doses)
- Chronic use: CV damage, liver damage (fatty liver to cirrhosis), erosive gastritis and GI bleeding, acute pancreatitis, sexual dysfunction
- Withdrawal manifestations: inability to sleep, ^ HR, transient hallucinations or illusions, anxiety, ^ BP, ^RR, ^temp., tonic-clonic seizure
- — delirium can occur 2-3 days after cessation, MEDICAL EMERGENCY. Manifest as severe disorientation, psychotic manifestations (hallucinations), severe htn, dysrhythmias, delirium. Delirium can progress to death
CNS depressant: sedative/ hypnotics/ anxiolytics
ex. club drug
Benzodiazepines (diazepam), barbiturates (phenobarbital), club drugs (flunitrazepam “rape drug”) can be injected or taken orally
intended to decrease anxiety, sedation
Effects of intoxication
- ^drowsiness, sedation, agitation, slurred speech, uncoordinated motor activity, nystagmus, disorientation, n&v
- resp. depression and decreased LOV, can be fatal
***antidote- flumazenil IV for benzo. toxicity
no antidote for barbiturate toxicity
Withdrawal manifestations: anxiety, insomnia, deaphoresis, htn, psychotic reactions, hand tremors, n&v, hallucinations/ illusions, psychomotor agitation, possible seizures
CNS depressant:
Cannabis
marijuana or hashish (more potent) can be smoked or ingested
intended effects: euphoria, sedation, hallucinations, decrease of n&v (chemo), chronic pain management
effects of intoxication
- chronic use: ^risk for lung cancer, resp. effects, problems with ADL
- in high doses: occurrence of paranoia (delusions and hallucinations)
- ^appetite, dry mouth, tachycardia
- can impair motor skills up to 8-12 hrs.
- synthetic; K2 and spice, have been associated w/ toxic doses.
withdrawal manifestations: irritability, aggression, anxiety, insomnia, lack of appetite, restlessness, depressed mood, abd. pain, tremors, diaphoreses, fever, headache
CNS stimulants: Cocaine
injected, smoked, or inhaled
intended effects: rush of euphoria, pleasure, ^energy
effects of intoxication
- mild toxicity- dizziness, irritability, tremor, blurred vision
- severe effects- hallucinations, seizures, extreme fever, tachycardia, htn, chest pain, possible cv collapse and death
Withdrawal manifestations:
- depression, fatigue, craving, excess sleeping or insomnia, dramatic unpleasant dreams, psychomotor retardation, agitation
- not life-threatening but possible suicidal ideation
CNS stimulants: Amphetamines
orally, injected IV, or smoked
intended effects: ^energy, euphoria similar to cocaine
effects of intoxication:
- impaired judgement, psychomotor agitation, hypervigilance, extreme irritability
- acute cv effects (tachycardia, ^BP) which could cause death
withdrawal manifestations:
- craving, depression, fatigue, sleeping
- not life-threatening
CNS stimulants: Inhalants
amyl nitrate, nitrous oxide, solvents are sniffed, huffed, or bagged often by children or adolescents
intended effects: euphoria
Effects of intoxication:
- depend on substance, but generally can cause behavioral/ psychological changes, dizziness, nystagmus, uncoordinated movements or gait, slurred speech, drowsiness, hyporeflexia, muscle weakness, diplopia, stupor or coma, resp. depression, possible death
- withdrawal manifestations: none
Medications for substance withdrawal
Alcohol withdrawal- diazepam, cabamazepine, clonidine, chlordiazepoxide, phenobarbital, naltrexone
Alcohol abstinence- disulfiram, naltrexone, acamprosate
Opioid withdrawal- methadone substitution, clonidine, buprenorphine, naltrexone, levo- alpha- acetylmethadol
Nicotine withdrawal from tobacco use- bupropion, nicotine replacement therapy (nicotine gum and nicotine patch), varenicline, bupropion
Nicotine abstinence- varenicline, rimonabant
Psychotherapies for substance disorders
- cognitive behavioral therapies (relaxation techniques or cognitive reframing)
- acceptance and commitment therapy (ACT)
- relapse prevention therapy assists clients in identifying the potential for relapse and promotes behavioral self-control
12 step program and family groups
Alcoholics Anonymous, Narcotics Anonymous, Gambler’s Anonymous
family groups: Al-Anon, Ala-Teen
These programs will teach;
- abstinence is necessary for recovery
- a higher power is needed to assist in recovery
- clients are not responsible for their disease but are responsible for their recovery
- other people cannot be blamed for the client’s addictions, and they must acknowledge their feelings and problems