Mod 6 Flashcards
CATBITES stands for?
Congenital Arthritis Trauma Blood Infection Tumour Endocrine/metabolic/nutritional Soft tissue
Types of tumours?
Benign and malignant
Types of malignant tumours?
Primary (30%)
Secondary aka metastasis (70%)
What is used in imaging tumours?
Initially plain film / digital imaging
10 determinants of lesion aggressiveness?
Age of patient ST involvement Pattern of destruction Size of lesion Location of lesion Zone of transition Margination of lesion Presence of visible tumour matrix Host response Monostotic or polystotic
M.C Malignant osseous lesion in <1 yoa
Usually metastatic neuroblastoma
M.C tumour in 1-30 yoa
osteosarcoma or Ewing’s sarcoma
m.c tumour in 30-60 yoa
chondrosarcoma, primary lymphoma, or malignant fibrous histiocytoma
m.c. tumour in >50
metastatic disease or multiple myeloma
Benign tumours are more common in (old/young)?
young
Malignant tumours are more common in (old/young)?
old
What does a soft tissue mass indicate?
Primary malignant tumour or infection
What does the absence of a ST mass indicate?
Benign or metastasis
Types of osteolytic lesions (3)
Geographic (least aggressive; benign or infection)
Moth-eaten (more aggressive; malignant or infection)
Permeative (most aggressive; malignant)
Types of osteoblastic lesions (2)
Diffuse ivory-like
localized (snowball)
In terms of size of lesion, what size is more likely to be malignant or aggressive?
> 5cm (but this is a poor predictor, and there are many exceptions)
Benign lesions size/shape?
slow growing- along axis of bone- long lesion in a long bone
most are <6cm
(poor predictors)
Agressive lesion size/shape?
rapid growing- no definitive shape- amorphous
any size
(poor predictors)
Sclerotic margin with narrow transition zone suggests?
non-aggressive
Non sclerotic margin with wide zone of transmission suggests?
aggressive
Aggressive bone-forming tumours produce?
amorphous osteoid which is often less dense than normal bone
Less aggressive bone-forming tumours produce?
better organized, denser bone
Cartilage producing tumours are:
distinctive, stippled and more dense than normal bone
An host will respond quickly to aggressive lesions (T/F)
F- no time to respond; cortical destruction; penetration of ST; with or without periosteal rxn
