mod 3 Flashcards
What is Diabetes Mellitus?
Endocrine disorder in which the pancreas cannot produce adequate insulin to regulate glucose levels
Includes both Type 1 and Type 2 diabetes.
What is Gestational Diabetes Mellitus?
Any degree of glucose intolerance or abnormal glucose metabolism with the onset occurring during pregnancy.
When is insulin released?
When the sugar level of the blood is high, insulin is released to regulate blood glucose levels.
What is the usual concern in Diabetes Mellitus?
Hyperglycemia.
What is the goal of treatment for diabetes during pregnancy?
Controlling balance between insulin and blood glucose to prevent hyper/hypoglycemia.
Why does Gestational Diabetes Mellitus (GDM) happen?
Resistance to insulin caused by the effect of maternal hormones on beta cells of the pancreas.
Can a non-diabetic pre-pregnancy develop Gestational Diabetes Mellitus?
Yes, less than 5% (2–3%) of non-diabetic patients develop GDM during pregnancy.
What are the major maternal risks associated with Gestational Diabetes Mellitus?
- Hypertension and/or preeclampsia
- UTI
- Ketoacidosis
- Labor dystocia or obstructed delivery
- Postpartum hemorrhage
- Hematoma and lacerations.
What fetal risks are associated with Gestational Diabetes Mellitus?
- Congenital anomalies
- Perinatal death
- Macrosomia
- Intrauterine growth retardation (IUGR)
- Birth injury
- Hypoglycemia
- Polycythemia
- Hyperbilirubinemia
- Hypocalcemia.
What is Type 1 Diabetes Mellitus characterized by?
Destruction of the beta cells in the pancreas that usually leads to absolute insulin deficiency.
How is Type 2 Diabetes Mellitus managed?
Dependent on oral hypoglycemic agents and synthetic insulin together with diet and exercise.
What is impaired glucose homeostasis?
A state between ‘normal’ and ‘diabetes’ where the body is no longer using or secreting insulin properly.
What are the signs of maternal hypoglycemia?
- Shaking/tremors
- Sweating
- Pallor
- Disorientation
- Hunger
- Blurred vision.
What are the signs of maternal hyperglycemia?
- Fatigue
- Flushed skin
- Dry mouth
- Frequent urination
- Rapid, deep respirations
- Drowsiness
- Depressed reflexes.
What is the normal serum glucose level?
80–120 mg/dL.
What is the diagnostic value for pre-diabetic fasting blood glucose?
101–125 mg/dL.
What is the procedure for diagnosing diabetes?
A blood sample is taken to check glucose levels; fasting for 8 to 12 hours is required.
What does glycosuria indicate?
The kidneys begin to excrete quantities of glucose in the urine to lower serum glucose levels.
What causes polyuria in diabetes?
Increased urination due to osmotic action of glucose in the urine.
What is the effect of maternal vascular impairment on the fetus?
Poor placental perfusion leading to perinatal death.
What is the risk of having a macrosomic fetus?
Stimulates production of insulin, leading to potential complications during delivery.
What are the nursing responsibilities for blood glucose monitoring?
- Wash hands before puncturing
- Use sides of fingers for puncture
- Wipe away the first drop of blood.
Fill in the blank: The presence of glucose in urine is referred to as _______.
glycosuria.
True or False: Gestational diabetes can signal an increased risk for type 2 diabetes later in life.
True.
What technique should be used to decrease sensation of pain during injections?
Use sides of fingers instead of ends
What should be done with the first drop of blood during a blood test?
Wipe away the first drop
What is the purpose of the Oral Glucose Challenge Test?
To check for risk of GDM
At what gestational weeks is the Oral Glucose Challenge Test typically performed?
24–38 weeks AOG
What fasting serum glucose level confirms a diagnosis of diabetes?
126 mg/dL or above
What non-fasting serum glucose level indicates diabetes?
200 mg/dL or above
What is the glucose load ingested during the Oral Glucose Challenge Test?
50-g glucose load
What serum glucose level after 1 hour indicates the need for a 100-g, 3-hour fasting glucose tolerance test?
> 140 mg/dL
What fasting glucose level indicates GDM if 2/4 abnormal blood samples are found?
> 95 mg/dL
What does Glycosylated Hemoglobin (HbA1C) measure?
The average glucose level over the past 4–6 weeks
What is the upper normal level of HbA1C?
6% of total hemoglobin
What happens to glucose attached to hemoglobin as blood sugar increases?
It increases
When was insulin produced synthetically?
1921
What is the gold standard for management of diabetes?
Insulin administration
What type of insulin is combined with short-acting insulin for diabetes management?
Intermediate type
What occurs in early pregnancy that affects insulin levels?
Lower synthetic insulin
What hormones stimulate normal insulin production during early pregnancy?
Estrogen and progesterone
In late pregnancy, why is there a higher need for synthetic insulin?
Increased glucose used by woman and fetus
What is the recommended starting insulin dose distribution?
2/3 in the morning, 1/3 in the evening
What should be avoided in pregnancy regarding oral hypoglycemic agents?
They can cross the placenta and are teratogenic
What is the correct order for drawing insulin?
Inject air to intermediate insulin first, then to regular insulin
What should be done with insulin before administration to avoid pain?
Warm at room temperature
How should insulin be injected to minimize leakage?
Inject slowly (2-4 seconds)
What should patients with hypoglycemia consume?
A glass of milk and crackers
What is the recommended action for hyperglycemia?
Assess urine for ketones and inform healthcare provider
How often should blood glucose be monitored?
At least 4 times a day
What is the normal creatinine clearance value?
0.7-1 mg/dL
What does the Lecithin-Sphingomyelin (L:S) ratio determine?
Fetal lung maturity
What is the expected L:S ratio for a mature fetus?
1:2
What is the preferred method of delivery for patients with GDM?
Vaginal birth
What is the risk associated with cesarean birth in GDM patients?
Higher risks including exacerbated hyperglycemia
What happens to maternal glucose levels after delivery?
They usually return to normal
What is the risk for women who had diabetes pre-pregnancy?
50-60% risk for developing Type 2 DM later in life
What dietary control should be maintained during pregnancy?
Adequate glucose intake to prevent hypoglycemia
What is the recommended weight gain during pregnancy for women with GDM?
25-30 lbs
What is a potential nursing diagnosis related to GDM?
Risk for ineffective tissue perfusion
What should be monitored closely in cases of hydramnios?
Uterine contraction and risk for hemorrhage
What is the recommended weight gain during pregnancy to limit fetus size?
25-30 lbs
What is the minimum caloric intake recommended for pregnant women?
1800 calories
What macronutrient distribution is recommended in a 1800–2400 calorie diet?
- 20% protein (CHON)
- 40-50% carbohydrates (CHO)
- 30% fats
What should pregnant women do to prevent hypoglycemia during the night?
Encourage protein and complex carbohydrates at night
True or False: Pregnant women are most vulnerable to hypoglycemia at night.
True
What types of foods are recommended for pregnant women to maintain stable glucose levels?
- Rice
- Breads
- Oats
- Spaghetti
- Cassava
- Potatoes
- Egg
- Whole grain toast
- Hummus
- Whole grain crackers
What are the benefits of exercise during pregnancy?
- Lowers blood sugar
- Helps with weight control
- Improves glucose metabolism
- Provides cardiopulmonary benefits
What should be done if uterine contractions occur during exercise?
Stop walking, hydrate, and rest in a side-lying position
What is the percentage of pregnant women who use illegal drugs?
20-30%
List some fetal effects of cocaine use during pregnancy.
- Hyperarousal state
- Increased STIs
- Spontaneous abortion
- Abruptio placenta
- Pre-eclampsia
- Premature labor
True or False: Marijuana use during pregnancy can lead to reduced milk production.
True
What are the effects of tobacco use during pregnancy?
- Low maternal perfusion
- Abruptio placenta
- Preterm labor
- Increased risk of SIDS
What are the risks associated with alcohol use during pregnancy?
- Spontaneous abortion
- Fetal alcohol spectrum disorder (FASD)
- Intrauterine growth restriction (IUGR)
Fill in the blank: HIV is transmitted from _______.
[person-to-person]
What is the significance of the CD4 count in HIV patients?
A CD4 count below 500 cells/mm3 indicates risk for opportunistic infections
What is the role of antiretroviral therapy (ART) in HIV-positive pregnant women?
Decreases viral load and reduces transmission risk to the infant
What are early symptoms of HIV in pregnant women?
- Fatigue
- Anemia
- Diarrhea
- Progressive weight loss
What substance abuse treatment groups are available for pregnant women?
- Alcoholics Anonymous (AA)
- Cocaine Anonymous (CA)
- Heroin Anonymous (HA)
- Marijuana Anonymous (MA)
- Nicotine Anonymous (NicA)
- Narcotics Anonymous (NA)
- Pills Anonymous (PA)
What are common withdrawal symptoms from substance abuse?
- Nausea and vomiting
- Diarrhea
- Abdominal pain
- HPN (Hypotension)
- Shivering
What is the most serious STI affecting pregnant women and their infants?
HIV/AIDS
What is the effect of caffeine on pregnant women?
Stimulates CNS and cardiac function, crosses the placental barrier
What should be monitored during labor for women with a history of substance abuse?
Electronic fetal monitoring, contractions, and fetal heart tones (FHT)
What is the risk of maternal-fetal transmission of HIV if untreated?
15-35%
True or False: HIV is curable.
False
What CD4 count is usually associated with a higher chance for opportunistic infections?
<200 cells/mm3
A CD4 count lower than 200 cells/mm3 indicates a higher risk for opportunistic infections.
What is a key preventive measure against opportunistic infections?
Maintain a higher CD4 count
A higher CD4 count helps in reducing the chances of opportunistic infections.
What are risk factors for opportunistic infections?
- Multiple sexual partners
- Bisexual partners
- IV drug use with shared needles
- Blood transfusion
- Vertical transmission
These factors increase the exposure to HIV and other infections.
True or False: HIV can be transmitted through saliva.
False
The presence of the virus in saliva is extremely low, making transmission via saliva unlikely.
What are some maternal complications associated with HIV?
- Intrapartum and postpartum hemorrhage
- Poor wound healing
- GU infections
- Fever
- Swollen lymph nodes
- Recurrent respiratory tract infections
- Oral candidiasis
- Preterm births
- Small for gestational age
- Failure to thrive
- Enlarged spleen and liver
These complications arise due to the effects of HIV on the immune system.
What is the normal range for CD4 cell count?
> 500 T4 cells/mm3
Maintaining a CD4 count above this level is crucial for immune health.
What does the Polymerase Chain Reaction (PCR) test check for in HIV diagnosis?
Level of antigens in the blood
PCR tests are important for detecting the presence of HIV antigens.
What is the most commonly used screening test for HIV?
Enzyme-Linked Immunosorbent Assay (ELISA)
A positive ELISA test requires a confirmatory test, such as the Western blot.
What is the purpose of administering Zidovudine (AZT)?
Prevents progressive deterioration of the immune system
Zidovudine is administered to reduce the risk of opportunistic infections.
What are the potential adverse effects of Zidovudine?
- Nausea
- Loss of appetite
- Paresthesia
- Headache
- Fever
- Agranulocytopenia
- Thrombocytopenia
These side effects necessitate careful monitoring during treatment.
What is the role of Rh immune globulin (RhIG) in pregnancy?
Prevents the mother from forming natural antibodies against Rh-positive blood
RhIG is administered to Rh-negative women to prevent Rh sensitization.
What happens during Rh sensitization?
The mother forms antibodies against Rh-positive blood
This immune response can lead to hemolytic disease of the newborn in subsequent pregnancies.
What fetal effects can result from hemolysis due to Rh sensitization?
- Enlarged liver and spleen
- Vascular hypertonicity
- Congestive heart failure
- Hydrops fetalis
- Anemia
- Hyperbilirubinemia
These conditions arise from the destruction of fetal red blood cells.
What does the Doppler velocity of fetal middle cerebral artery indicate?
Predicts fetal anemia or destruction of fetal RBCs
Monitoring this velocity helps assess the risk of hemolytic disease.
What is the significance of a high ratio in anti-D antibody titer?
Indicates Rh sensitization
A ratio of 1:16 or above necessitates monitoring and potential interventions.
Fill in the blank: HIV can be transmitted through _______.
Body secretions
This includes semen, vaginal fluids, and breastmilk.
What is the goal of medical management for HIV?
Maintain the CD4 cell count at greater than 500 cells/mm3
This goal is critical for sustaining the immune system.
What procedure is used to determine the blood type of the baby?
PUBS
PUBS stands for Percutaneous Umbilical Blood Sampling.
What is the purpose of injecting RBCs directly into a vessel in the fetal cord?
Restore fetal RBCs
When should RBCs be given to the fetus?
When hematocrit levels are less than 30% intravascularly/intraperitoneally
How much washed red cells are typically used in fetal transfusion?
75–150 mL
What is a potential complication of the procedure involving RBC injection?
Lacerations in cord blood vessel
What is the most common type of anemia during pregnancy?
Iron-deficiency anemia
What is pseudoanemia?
A condition where blood volume expands during pregnancy slightly ahead of the red cell count
What is the normal hemoglobin level for the 1st trimester of pregnancy?
<11 g/dL
What dietary factors contribute to iron-deficiency anemia in pregnancy?
Low iron diet, heavy menstrual periods, unhealthy weight-reducing programs
What is a characteristic of iron-deficiency anemia?
Microcytic and hypochromic anemia
What are common symptoms of iron-deficiency anemia?
Pallor, fatigue, lethargy, headache, tachycardia
What is pica?
Persistent craving and compulsive eating of non-food substances
What dietary recommendations are made for iron-deficiency anemia?
Eat a diet high in iron and vitamins, such as organ meats, shellfish, spinach, legumes
What is the recommended daily dosage of folic acid for pregnant women?
400 mcg daily; 800 mcg for those currently pregnant
What are the maternal complications of folic acid-deficiency anemia?
Spontaneous abortion, abruptio placenta, neural tube defects
What is pregnancy-induced hypertension (PIH)?
Condition with vasospasm during pregnancy leading to hypertension
What are the clinical manifestations of PIH?
Hypertension, proteinuria, and edema
What is the cure for pregnancy-induced hypertension?
After birth of the infant
What is the significance of elevated diastolic blood pressure in preeclampsia?
Indicates the degree of peripheral arterial spasm present
What is mild preeclampsia characterized by?
BP of 140/90 mmHg with proteinuria 1+ or 2+
What is a common dietary advice for iron supplementation?
Take iron supplements with orange juice or a vitamin C supplement
What is the effect of vasospasm in PIH on fetal health?
Reduced fetal nutrient and oxygen supply
What are the risk factors for developing pregnancy-induced hypertension?
Women of color, multiple pregnancies, primiparas younger than 20 or older than 40
True or False: The body requires more blood volume during pregnancy, leading to increased risk of anemia.
True
Fill in the blank: The highest need for iron during pregnancy is in the _______.
third trimester
What defines REECLAMPSIA?
Abnormal assessment results taken on two occasions, at least 6 hours apart at bed rest.
What is the blood pressure threshold for diagnosing high blood pressure in REECLAMPSIA?
BP of 160/110 mmHg or above.
What constitutes proteinuria in the context of REECLAMPSIA?
3+ or 4+ proteinuria, or 5g/24h urine collection.
What is the significance of extreme edema in REECLAMPSIA?
It indicates severe depletion of albumin in the blood.
What are the characteristics of pitting edema?
Edematous tissue can be indented; scored as follows:
* 1+: slight indentation
* 2+: moderate indentation
* 3+: deep indentation
* 4+: remains after removal of finger.
What indicates non-pitting edema?
Edematous tissue cannot be indented with finger pressure; caused by excess lymphatic fluid.
What are common additional signs and symptoms of REECLAMPSIA?
- Reduced urine output/oliguria (400–600 mL per 24 hours)
- Severe epigastric pain, nausea, and vomiting
- Shortness of breath, coughing, and dyspnea from pulmonary edema
- Visual disturbances
- Severe headache, hyperreflexia, and ankle clonus.
What is the laboratory value for platelet count in REECLAMPSIA?
Platelet count <100,000.
What is ECLAMPSIA?
Most severe stage of PIH with a high maternal mortality rate of 20%.
What are the phases of a tonic-clonic seizure in ECLAMPSIA?
Tonic Phase (20 seconds) and Clonic Phase (up to 1 minute).
What is the role of antihypertensive drugs in managing REECLAMPSIA?
Promotes vasodilation.
What is the therapeutic range for magnesium sulfate?
5–8 mg/dL.
What are signs of magnesium sulfate toxicity?
- Blood pressure decreased
- Urine output decreased (oliguria)
- Respiratory depressions <12
- Patellar reflex absent.
What is the antidote for magnesium toxicity?
Calcium gluconate.
What nursing diagnosis is associated with REECLAMPSIA?
Ineffective tissue perfusion related to vasoconstriction of blood vessels.
What are nursing interventions for mild PIH?
- Promote bed rest at home
- Lateral recumbent position
- Good nutrition
- Monitor antiplatelet therapy.
What is the significance of a premonition or aura in ECLAMPSIA?
It indicates that a seizure is about to occur.
How should a patient be positioned during a seizure?
Turn the woman on her side to prevent aspiration.
What is the recommended management for postpartum hypertension?
Monitor blood pressure.
Fill in the blank: Severe epigastric pain, nausea, and vomiting may indicate ______.
abdominal edema and ischemia to pancreas and liver.
True or False: A cesarean section is preferred over a normal spontaneous delivery in cases of proteinuria, edema, and hypertension.
False.
When does ENTION typically occur after delivery?
10–14 days after delivery
When does ENTION usually occur in relation to birth?
In the first 48 hours after birth
What should be monitored in a patient with ENTION?
BP
Which of the following is a sign of DM?
A) Weight gain
B) Metabolic alkalosis
C) Hypoglycemia
D) Polydipsia
D) Polydipsia
Which test is more accurate for diagnosing DM?
HbA1C
What is the most useful health teaching regarding insulin for a pregnant client with DM?
Rotate injection sites
Caloric needs of a pregnant client with DM should mainly consist of:
Carbohydrates
Which age group is at risk of substance abuse during pregnancy?
Young adults with abusive parents
What is the confirmatory test in the diagnosis of HIV?
Western blot test
When should RhIG be administered to protect the succeeding pregnancy?
In the first 72 hours after delivery
Which health teaching will benefit a pregnant client taking iron supplements?
Take the iron tablets with orange juice
The following are triad symptoms of PIH except:
Proteinuria
What is the drug of choice in PIH?
Magnesium sulfate
What is an appropriate intervention when a pregnant client with PIH experiences seizures?
Turn the head to the side