Mock Tests Review Flashcards
Mutation seen in follicular thyroid cancer ?
RAS mutation
Mutation in papillary thyroid cancer
BRAF
RET
MET
HOW WILL YOU differentiate b/w AML M2 & M3 ?
AML M2- very few auer rods will be seen
AML M3- large number of Auer rods are seen
Common mutation seen in
- AML M2-
- AML M3
- AML M4
- AML M7
- T(8;21)
- T(15;17)- PML-RARA
- INVERSION 16
- Inversion 3
What is chemodectoma ?
A rare neural tumor of carotid body seen later in 5th decade of life
Cause of malabsorption in Whipple’s disease ?
Lymphatic obstruction by bacteria containing macrophages
M/c site in stomach for gastric adenocarcinoma in INdia and in world ?
India- antrum
World- cardia
Pattern of fibrosis in each - NASH & Alcoholic liver disease
NASH- periportal
ALD- peri sinusoidal and perivenular
What happens if Rb gene is hypophosphorylated ?
Cell cycle stops at G1
All trans retinoids acid is used in t/t for which genetic aberration ?
PML-RARA: t(15;17)
In t/t of APML
Various Gleason pattern in Gleason scoring for prostate cancer
Pattern 3- well defined glandular pattern
Pattern 4- cribriform, distorted glandular
Pattern 5- malignant cells are visible all over
There is no pattern 1 & 2
Current range of Gleason score
6-10
Serotoli cell secretes
FSH
Inhibin- under negative feedback during normal spermatogenesis
Various deficit findings in Di-George syndrome
C- cardiac defects A- abnormal facies T- thymine aphasia C- cleft lip H- hypocalcemia 22- Chrm 22 abnormality
Onion skin thickening of vascular wall is seen in
Severe hypertension
Increased incidence of cancer in old age is due to
Telomerase reactivation
What can be done to prevent febrile non-hemolytic transfusion reaction ?
Leucoreduction of RBCs
Wilms tumor is a/w which all syndromes ?
WAGR
Denys-Drash
Beckwith Weidman
Presentation of WAGR syndrome
Wilms tumor
Aniridia
Genitourinary abnormality
Mental retardation
Wilms tumor gene is located on chromosome
11
