Mock Exam Flashcards
Proteins with more than one polypeptide are always
multimeric
A single nucleotide polymorphism is a variation in DNA which occurs at an allele frequency of at least 5% in one or more human populations T or F
False
A single nucleotide polymorphism is a variation in DNA that does not cause disease T or F
False
A point mutation can cause a silent allele T or F
True
a deletion can cause a silent allele T or F
True
an insertion can cause a silent allele T or F
True
Next Generation Sequencing is based on
sequencing by synthesis
A 20 yr old man has a sister who dies from an autosomal recessive disorder that is fatal with 2 years after birth what is the probability that this man is a heterozygous carrier of this disorder
2/3
Southern blot analysis reveals a size difference of the target band detected by the probe between 2 individuals which one of thee following possible causes for this difference is invalid
Splice Variance
Deficiency of an enzyme at one step of a pathway which blocks the effect of a variant of an enzyme at the next step in the pathway is an example of:
Epistasis
Inborn errors of metabolism are usually dominant T or F
False
Ascertainment may give misleading info about patterns of inheritance because of inbredding within famalies
False
