Mock 2 Flashcards

1
Q

which cancers a/w hypercalcaemia?

A

breast, lung, multiple myeloma (bone mets)

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2
Q

symptoms a/w electrolye disturbance in EDs

A

hypokalaemia - muscle weakness/cramps, fatigue

metabolic alkalosis - confusion, tremor, twitch, nausea, numbness

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3
Q

what is athetosis?

A

slow WRITHING movements of limbs (different to chorea which is quicker and more lurching)

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4
Q

movement disorder predominantly affecting lower limbs without tremor. difficulty in INITIATING movement predominates

A

normal pressure hydrocephalus

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5
Q

Chemical classes of antipsychotic FGA

A

Phenothiazines (aliphatic) - chlorpromazine
Phenothiazines (piperidine) - thioidazine
Butyrophenone - haloperidol
Thioxanthenes - flupenthixol, zuclopenthixol

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6
Q

Chemical classes of antipsychotic SGA

A

dibenzodiazepine - clozapine
dibenzothiazepine - quetiapine
thienobenzodiazepine - olanzapine
benzoxasoles - risperidone
substituted benzamide - (ami)sulpiride
arylpiperidylindone (quinolone) - aripiprazole

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7
Q

which antipsychotic binds to D1R

A

olanzapine

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8
Q

which cells use glutamate as a neurotransmitter

A
  1. pyramidal cells
  2. granular cells
  3. purkinje cells
  4. interneurons
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9
Q

what are chandelier cells?

A

GABAergic cortical interneurons

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10
Q

which cell conveys motor signals from cortex to spinal cord?

A

pyramidal

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11
Q

episodic vs declarative (explicit) memory?

A

episodic is serial events in time form we can construct actual events, has emotional change

declarative fact based eg what did you have for breakfast rather than tell me about your breakfast as a story

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12
Q

changes in extraversion, neuroticism, and psychoticism with age?

A

all decrease in men and women

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13
Q

conservation what is it and what stage of piaget?

A

water volumes in different shaped glasses

concrete operational

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14
Q

object constancy subphase of Mahlers?

A

2 years - 5 years

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15
Q

changes in matter in brain during adolescence

A

decrease in grey and increase in white matter

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16
Q

in strange situation (ainsworth) how many separation and reunion episode?

A

2 separation 2 reunion

17
Q

duration of puberty in boys?

A

2-3 years (2.4 yrs avg)

18
Q

duration of puberty in girls?

A

1.9 years avg

19
Q

duration of puberty range in both sexes

20
Q

time telling ability of children

A

4-5 (reception) - to hour
5-6 (year 1) - half hour
6-7 (year 2) - quarter hour

21
Q

late onset schizophrenia characteristics?

A

predominance females
fewer negative symptoms
infrequent FTD
prominent hallucination (notably visual)

22
Q

highest lvel of attention?

A

alternating

23
Q

applied pressure in which exposure therapy?

A

for blood-needle-injury (collapsing) phobia

24
Q

what does motivational interviewing aim to increase?

A

cognitive dissonance

25
fatality of untreated NMS
15-20%
26
common SE of valproate
weight gain nausea vomiting diarrhoea sedation tremor thrombocytopenia hair loss w/curly regrowth
27
hyperprolactinaemia associated antipsychotics
amisul sulp risp pali
28
which medication slows GI transit causing slow oral absorption
amitriptyline
29
antidep in pregnancy
SSRI
30
NOT a feature of NMS
bradycardia
31
MOA of priapism in trazodone
a1 BLOCKADE
32
PD med for influenza?
amantadine (prevent virus uncoating)
33
half life of risperidone
24hr
34
smith-magenis syndrome
self-hugging and self-picking. big jaw. 17p11.2 microdeletion
35
apraxia/dyspraxia what lobe?
dominant parietal